Format
Items per page

Send to:

Choose Destination

Links from PubMed

Items: 1 to 20 of 62

1.

Oxidative Stress

A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products. The damage to biological tissues is caused by superoxide and other free radicals generated by many factors, including exposure to alcohol, medications, trauma, cold, toxins, and radiation or by antimicrobial cellular immunity, metabolic abnormality, or "normal" aging; not synonymous with hypoxia or hyperoxia. Oxidative stress promotes a range of degenerative disorders, including cancer, diabetes, premature aging, Alzheimer's, and many others. [from NCI]

MedGen UID:
66929
Concept ID:
C0242606
Cell or Molecular Dysfunction
2.

Sulfur

An element that is a member of the chalcogen family. It has an atomic symbol S, atomic number 16, and atomic weight [32.059; 32.076]. It is found in the amino acids cysteine and methionine. [from MeSH]

MedGen UID:
11653
Concept ID:
C0038774
Biologically Active Substance; Element, Ion, or Isotope; Pharmacologic Substance
3.

Inflammation

A localized protective response resulting from injury or destruction of tissues. Inflammation serves to destroy, dilute, or wall off both the injurious agent and the injured tissue. In the acute phase, inflammation is characterized by the signs of pain, heat, redness, swelling, and loss of function. Histologically, inflammation involves a complex series of events, including dilatation of arterioles, capillaries, and venules, with increased permeability and blood flow; exudation of fluids, including plasma proteins; and leukocyte migration into the site of inflammation. [from NCI]

MedGen UID:
7072
Concept ID:
C0021368
Pathologic Function
4.

Silibinin

MedGen UID:
109053
Concept ID:
C0600334
Organic Chemical; Pharmacologic Substance
5.

Stress

The negative mental, emotional, and physical reactions that occur when environmental stressors are perceived as exceeding the individual's adaptive capacities. [from NCI]

MedGen UID:
20971
Concept ID:
C0038435
Finding
6.

Caprylic acid

A saturated medium-chain fatty acid with an 8-carbon backbone. Octanoic acid is found naturally in the milk of various mammals and is a minor component of coconut oil and palm kernel oil. [from NCI]

MedGen UID:
27008
Concept ID:
C0054616
Organic Chemical; Pharmacologic Substance
7.

DNA damage

Drug-, radiation-induced, or spontaneous injuries to DNA that introduce deviations from its normal double-helical conformation. These changes include structural distortions that interfere with replication and transcription, as well as point mutations that disrupt base pairs and exert damaging effects on future generations through changes in DNA sequence. If the damage is minor, it can often be repaired (DNA repair); extensive damage can induce apoptosis. [from NCI]

MedGen UID:
3880
Concept ID:
C0012860
Cell or Molecular Dysfunction
8.

Flavonolignans

Heterodimers of FLAVONOIDS bound to LIGNANS. [from MeSH]

MedGen UID:
226234
Concept ID:
C1257967
Organic Chemical; Pharmacologic Substance
9.

Carsil

MedGen UID:
154686
Concept ID:
C0600328
Organic Chemical; Pharmacologic Substance
10.

Legalon

MedGen UID:
109415
Concept ID:
C0600330
Organic Chemical; Pharmacologic Substance
11.

Karsil

MedGen UID:
109052
Concept ID:
C0600329
Organic Chemical; Pharmacologic Substance
12.

Physiological stress

The unfavorable effect of environmental factors (stressors) on the physiological functions of an organism. Prolonged unresolved physiological stress can affect HOMEOSTASIS of the organism, and may lead to damaging or pathological conditions. [from MeSH]

MedGen UID:
105278
Concept ID:
C0449430
Pathologic Function
13.

Collagenase product

Collagenases are enzymes that degrade collagen fibers. These enzymes play an important role in connective tissue metabolism and are produced by specific cells involved in both repair and remodeling processes. [from NCI]

MedGen UID:
102454
Concept ID:
C0162745
Amino Acid, Peptide, or Protein; Enzyme; Pharmacologic Substance
14.

Protease preparation

A class of enzymes that catalyze the hydrolysis of peptide bonds in the interior of a polypeptide chain or protein molecule. [from NCI]

MedGen UID:
45389
Concept ID:
C0030946
Amino Acid, Peptide, or Protein; Enzyme; Pharmacologic Substance
15.

Protective agent

A class of agents used in prophylactic or curative therapy to attenuate the negative side effects of toxins or drugs. Protective agents belong to various chemical classes, acting through various pharmacological mechanisms. They may neutralize exogenous poisons, coat mucosa for protection against physical or chemical damage, offer antioxidant protection against free radicals or ionizing radiation, or induce endogenous detoxifying enzymes. (NCI04) [from NCI]

MedGen UID:
19516
Concept ID:
C0033613
Pharmacologic Substance
16.

Purine nucleoside

Purines with a RIBOSE attached that can be phosphorylated to PURINE NUCLEOTIDES. [from MeSH]

MedGen UID:
18775
Concept ID:
C0034136
Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
17.

Silymarin

A mixture of flavonolignans isolated from the milk thistle plant Silybum marianum. Silymarin may act as an antioxidant, protecting hepatic cells from chemotherapy-related free radical damage. This agent may also promote the growth of new hepatic cells. (NCI04) [from NCI]

MedGen UID:
11433
Concept ID:
C0037135
Organic Chemical; Pharmacologic Substance
18.

Guanosine

A purine nucleoside formed from a beta-N9-glycosidic bond between guanine and a ribose ring and is essential for metabolism. [from NCI]

MedGen UID:
9106
Concept ID:
C0018330
Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
19.

Mustard Compounds

Strong alkylating and immunosuppressive agents whose biological activity is based on the presence of bis(2-chloroethyl)- groups. Although otherwise structurally diverse, the compounds have in common the capacity to contribute alkyl groups to DNA. They are generally highly toxic but include among their number many widely used and effective antineoplastic agents. [from MeSH]

MedGen UID:
7760
Concept ID:
C0026873
Hazardous or Poisonous Substance; Organic Chemical; Pharmacologic Substance
20.

Bioflavonoid preparation

Naturally occurring flavone or coumarin derivatives having the activity of the so-called vitamin P, notably rutin and esculin. [from NCI]

MedGen UID:
2254
Concept ID:
C0005492
Organic Chemical; Pharmacologic Substance; Vitamin
Format
Items per page

Send to:

Choose Destination

Supplemental Content

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center