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Glanders

MedGen UID:
42221
Concept ID:
C0017589
Disease or Syndrome
Synonyms: Equina; Equine glanders; Farcy; Farcy buds; Farcy cords; Farcy pipes; Infection due to Actinobacillus mallei; Infection due to Malleomyces mallei; Infection due to Pseudomonas mallei; Maliasmus; Malleus (glanders)
SNOMED CT: Farcy (4639008); Equina (4639008); Equine glanders (4639008); Farcy buds (4639008); Farcy pipes (4639008); Farcy cords (4639008); Glanders (4639008); Infection due to Pseudomonas mallei (4639008); Malleus (glanders) (4639008); Infection due to Actinobacillus mallei (4639008); Infection due to Malleomyces mallei (4639008); Maliasmus (4639008)
 

Definition

A contagious disease of horses that can be transmitted to humans. It is caused by BURKHOLDERIA MALLEI and characterized by ulceration of the respiratory mucosa and an eruption of nodules on the skin. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGlanders

Recent clinical studies

Etiology

Jelesijevic T, Zimmerman SM, Harvey SB, Mead DG, Shaffer TL, Estes DM, Michel F, Quinn FD, Hogan RJ, Lafontaine ER
PLoS One 2015;10(4):e0124181. Epub 2015 Apr 10 doi: 10.1371/journal.pone.0124181. PMID: 25860021Free PMC Article
Van Zandt KE, Greer MT, Gelhaus HC
Orphanet J Rare Dis 2013 Sep 3;8:131. doi: 10.1186/1750-1172-8-131. PMID: 24004906Free PMC Article
Lipsitz R, Garges S, Aurigemma R, Baccam P, Blaney DD, Cheng AC, Currie BJ, Dance D, Gee JE, Larsen J, Limmathurotsakul D, Morrow MG, Norton R, O'Mara E, Peacock SJ, Pesik N, Rogers LP, Schweizer HP, Steinmetz I, Tan G, Tan P, Wiersinga WJ, Wuthiekanun V, Smith TL
Emerg Infect Dis 2012 Dec;18(12):e2. doi: 10.3201/eid1812.120638. PMID: 23171644Free PMC Article
Zhang B, Wear DJ, Kim HS, Weina P, Stojadinovic A, Izadjoo M
Mil Med 2012 Feb;177(2):216-21. PMID: 22360070
Godoy D, Randle G, Simpson AJ, Aanensen DM, Pitt TL, Kinoshita R, Spratt BG
J Clin Microbiol 2003 May;41(5):2068-79. PMID: 12734250Free PMC Article

Diagnosis

Waag DM, England MJ, DeShazer D
Clin Vaccine Immunol 2012 May;19(5):814-6. Epub 2012 Mar 7 doi: 10.1128/CVI.05567-11. PMID: 22398248Free PMC Article
Zhang B, Wear DJ, Kim HS, Weina P, Stojadinovic A, Izadjoo M
Mil Med 2012 Feb;177(2):216-21. PMID: 22360070
Kumar S, Malik P, Verma SK, Pal V, Gautam V, Mukhopadhyay C, Rai GP
Clin Vaccine Immunol 2011 Sep;18(9):1456-61. Epub 2011 Jul 13 doi: 10.1128/CVI.05185-11. PMID: 21752949Free PMC Article
Gilad J
Recent Pat Antiinfect Drug Discov 2007 Nov;2(3):233-41. PMID: 18221181
Tiyawisutsri R, Holden MT, Tumapa S, Rengpipat S, Clarke SR, Foster SJ, Nierman WC, Day NP, Peacock SJ
BMC Microbiol 2007 Mar 15;7:19. doi: 10.1186/1471-2180-7-19. PMID: 17362501Free PMC Article

Therapy

Gregory AE, Judy BM, Qazi O, Blumentritt CA, Brown KA, Shaw AM, Torres AG, Titball RW
Nanomedicine 2015 Feb;11(2):447-56. Epub 2014 Sep 3 doi: 10.1016/j.nano.2014.08.005. PMID: 25194998Free PMC Article
Lafontaine ER, Zimmerman SM, Shaffer TL, Michel F, Gao X, Hogan RJ
PLoS One 2013;8(10):e76804. Epub 2013 Oct 2 doi: 10.1371/journal.pone.0076804. PMID: 24098563Free PMC Article
Silva EB, Dow SW
Front Cell Infect Microbiol 2013;3:10. Epub 2013 Mar 11 doi: 10.3389/fcimb.2013.00010. PMID: 23508691Free PMC Article
Estes DM, Dow SW, Schweizer HP, Torres AG
Expert Rev Anti Infect Ther 2010 Mar;8(3):325-38. doi: 10.1586/eri.10.4. PMID: 20192686Free PMC Article
Gilad J
Recent Pat Antiinfect Drug Discov 2007 Nov;2(3):233-41. PMID: 18221181

Prognosis

Zimmerman SM, Michel F, Hogan RJ, Lafontaine ER
PLoS One 2015;10(5):e0126437. Epub 2015 May 20 doi: 10.1371/journal.pone.0126437. PMID: 25993100Free PMC Article
Memišević V, Zavaljevski N, Rajagopala SV, Kwon K, Pieper R, DeShazer D, Reifman J, Wallqvist A
PLoS Comput Biol 2015 Mar;11(3):e1004088. Epub 2015 Mar 4 doi: 10.1371/journal.pcbi.1004088. PMID: 25738731Free PMC Article
Van Zandt KE, Greer MT, Gelhaus HC
Orphanet J Rare Dis 2013 Sep 3;8:131. doi: 10.1186/1750-1172-8-131. PMID: 24004906Free PMC Article
Chu KK, Tippayawat P, Walker NJ, Harding SV, Atkins HS, Maillere B, Bancroft GJ, Lertmemongkolchai G, Altmann DM
Eur J Immunol 2011 Jan;41(1):107-15. Epub 2010 Dec 3 doi: 10.1002/eji.201040881. PMID: 21182082Free PMC Article
Bossi P, Tegnell A, Baka A, Van Loock F, Hendriks J, Werner A, Maidhof H, Gouvras G; Task Force on Biological and Chemical Agent Threats, Public Health Directorate, European Commission, Luxembourg.
Euro Surveill 2004 Dec 15;9(12):E17-8. PMID: 15677841

Clinical prediction guides

Zimmerman SM, Michel F, Hogan RJ, Lafontaine ER
PLoS One 2015;10(5):e0126437. Epub 2015 May 20 doi: 10.1371/journal.pone.0126437. PMID: 25993100Free PMC Article
Memišević V, Zavaljevski N, Rajagopala SV, Kwon K, Pieper R, DeShazer D, Reifman J, Wallqvist A
PLoS Comput Biol 2015 Mar;11(3):e1004088. Epub 2015 Mar 4 doi: 10.1371/journal.pcbi.1004088. PMID: 25738731Free PMC Article
Lafontaine ER, Zimmerman SM, Shaffer TL, Michel F, Gao X, Hogan RJ
PLoS One 2013;8(10):e76804. Epub 2013 Oct 2 doi: 10.1371/journal.pone.0076804. PMID: 24098563Free PMC Article
Kumar S, Malik P, Verma SK, Pal V, Gautam V, Mukhopadhyay C, Rai GP
Clin Vaccine Immunol 2011 Sep;18(9):1456-61. Epub 2011 Jul 13 doi: 10.1128/CVI.05185-11. PMID: 21752949Free PMC Article
Chu KK, Tippayawat P, Walker NJ, Harding SV, Atkins HS, Maillere B, Bancroft GJ, Lertmemongkolchai G, Altmann DM
Eur J Immunol 2011 Jan;41(1):107-15. Epub 2010 Dec 3 doi: 10.1002/eji.201040881. PMID: 21182082Free PMC Article

Recent systematic reviews

Lipsitz R, Garges S, Aurigemma R, Baccam P, Blaney DD, Cheng AC, Currie BJ, Dance D, Gee JE, Larsen J, Limmathurotsakul D, Morrow MG, Norton R, O'Mara E, Peacock SJ, Pesik N, Rogers LP, Schweizer HP, Steinmetz I, Tan G, Tan P, Wiersinga WJ, Wuthiekanun V, Smith TL
Emerg Infect Dis 2012 Dec;18(12):e2. doi: 10.3201/eid1812.120638. PMID: 23171644Free PMC Article
Bossi P, Tegnell A, Baka A, Van Loock F, Hendriks J, Werner A, Maidhof H, Gouvras G; Task Force on Biological and Chemical Agent Threats, Public Health Directorate, European Commission, Luxembourg.
Euro Surveill 2004 Dec 15;9(12):E17-8. PMID: 15677841

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