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Malaria

MedGen UID:
7443
Concept ID:
C0024530
Disease or Syndrome
Synonyms: Fever, Marsh; Fever, Remittent; Infection, Plasmodium; Infections, Plasmodium; Marsh Fever; Paludism; Plasmodium Infection; Plasmodium Infections; Remittent Fever
Modes of inheritance:
not inherited
MedGen UID:
832438
Concept ID:
CN227390
Intellectual Product
Source: Orphanet
Describes a disorder that is not inherited.
not inherited (Orphanet)
SNOMED CT: Malaria (61462000); Paludism (61462000); Plasmodiosis (61462000); Disease due to Plasmodiidae (105649009); Disease caused by Plasmodiidae (105649009); Malarial fever (248437004)
 
Orphanet: ORPHA673

Definition

Malaria is a serious disease caused by a parasite. You get it when an infected mosquito bites you. Malaria is a major cause of death worldwide, but it is almost wiped out in the United States. The disease is mostly a problem in developing countries with warm climates. If you travel to these countries, you are at risk. There are four different types of malaria caused by four related parasites. The most deadly type occurs in Africa south of the Sahara Desert. Malaria symptoms include chills, flu-like symptoms, fever, vomiting, diarrhea, and jaundice. A blood test can diagnose it. It can be life-threatening. However, you can treat malaria with drugs. The type of drug depends on which kind of malaria you have and where you were infected. Malaria can be prevented. When traveling to malaria-prone regions. - See your doctor for medicines that protect you . - Wear insect repellent with DEET . - Cover up. - Sleep under mosquito netting . Centers for Disease Control and Prevention.  [from MedlinePlus]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalaria
Follow this link to review classifications for Malaria in Orphanet.

Recent clinical studies

Etiology

Adeola AM, Botai OJ, Olwoch JM, Rautenbach CJ, Adisa OM, Taiwo OJ, Kalumba AM
Trop Med Int Health 2016 May;21(5):675-86. Epub 2016 Mar 3 doi: 10.1111/tmi.12680. PMID: 26914617
Lupi O, Ridolfi F, da Silva S, Zanini GM, Lavigne A, Nogueira RM, da Cruz Mde F, Daniel-Ribeiro CT, Brasil P
Int J Infect Dis 2016 Mar;44:20-4. Epub 2016 Jan 22 doi: 10.1016/j.ijid.2016.01.008. PMID: 26809125
Tagbor H, Antwi GD, Acheampong PR, Bart Plange C, Chandramohan D, Cairns M
Trop Med Int Health 2016 Feb;21(2):224-35. Epub 2015 Dec 16 doi: 10.1111/tmi.12642. PMID: 26578353Free PMC Article
Smithson P, Florey L, Salgado SR, Hershey CL, Masanja H, Bhattarai A, Mwita A, McElroy PD; Tanzania Malaria Impact Evaluation Research Group.
PLoS One 2015 Nov 4;10(11):e0141112. doi: 10.1371/journal.pone.0141112. PMID: 26536354Free PMC Article
Kamuliwo M, Kirk KE, Chanda E, Elbadry MA, Lubinda J, Weppelmann TA, Mukonka VM, Zhang W, Mushinge G, Mwanza-Ingwe M, Haque U
Trans R Soc Trop Med Hyg 2015 Aug;109(8):514-21. Epub 2015 Jul 9 doi: 10.1093/trstmh/trv049. PMID: 26160256

Diagnosis

Carias C, Greening B Jr, Campbell CG, Meltzer MI, Hamel MJ
Lancet Infect Dis 2016 Apr;16(4):449-58. Epub 2015 Dec 17 doi: 10.1016/S1473-3099(15)00465-X. PMID: 26706716
Tagbor H, Antwi GD, Acheampong PR, Bart Plange C, Chandramohan D, Cairns M
Trop Med Int Health 2016 Feb;21(2):224-35. Epub 2015 Dec 16 doi: 10.1111/tmi.12642. PMID: 26578353Free PMC Article
Ndhlovu M, Nkhama E, Miller JM, Hamer DH
Trop Med Int Health 2015 Dec;20(12):1696-706. Epub 2015 Sep 29 doi: 10.1111/tmi.12591. PMID: 26311240
Fernando SD, Ainan S, Premaratne RG, Rodrigo C, Jayanetti SR, Rajapakse S
Int Health 2015 Sep;7(5):317-23. Epub 2015 Jul 22 doi: 10.1093/inthealth/ihv046. PMID: 26204895
Kamuliwo M, Kirk KE, Chanda E, Elbadry MA, Lubinda J, Weppelmann TA, Mukonka VM, Zhang W, Mushinge G, Mwanza-Ingwe M, Haque U
Trans R Soc Trop Med Hyg 2015 Aug;109(8):514-21. Epub 2015 Jul 9 doi: 10.1093/trstmh/trv049. PMID: 26160256

Therapy

Tagbor H, Antwi GD, Acheampong PR, Bart Plange C, Chandramohan D, Cairns M
Trop Med Int Health 2016 Feb;21(2):224-35. Epub 2015 Dec 16 doi: 10.1111/tmi.12642. PMID: 26578353Free PMC Article
Wragge SE, Toure D, Coetzee M, Gilbert A, Christian R, Segoea G, Hunt RH, Coetzee M
Trans R Soc Trop Med Hyg 2015 Dec;109(12):755-62. doi: 10.1093/trstmh/trv089. PMID: 26626339
Smithson P, Florey L, Salgado SR, Hershey CL, Masanja H, Bhattarai A, Mwita A, McElroy PD; Tanzania Malaria Impact Evaluation Research Group.
PLoS One 2015 Nov 4;10(11):e0141112. doi: 10.1371/journal.pone.0141112. PMID: 26536354Free PMC Article
Draper SJ, Angov E, Horii T, Miller LH, Srinivasan P, Theisen M, Biswas S
Vaccine 2015 Dec 22;33(52):7433-43. Epub 2015 Oct 11 doi: 10.1016/j.vaccine.2015.09.093. PMID: 26458807Free PMC Article
Ndhlovu M, Nkhama E, Miller JM, Hamer DH
Trop Med Int Health 2015 Dec;20(12):1696-706. Epub 2015 Sep 29 doi: 10.1111/tmi.12591. PMID: 26311240

Prognosis

Adeola AM, Botai OJ, Olwoch JM, Rautenbach CJ, Adisa OM, Taiwo OJ, Kalumba AM
Trop Med Int Health 2016 May;21(5):675-86. Epub 2016 Mar 3 doi: 10.1111/tmi.12680. PMID: 26914617
Hu Y, Zhou G, Ruan Y, Lee MC, Xu X, Deng S, Bai Y, Zhang J, Morris J, Liu H, Wang Y, Fan Q, Li P, Wu Y, Yang Z, Yan G, Cui L
Acta Trop 2016 May;157:12-9. Epub 2016 Jan 23 doi: 10.1016/j.actatropica.2016.01.022. PMID: 26812008Free PMC Article
Tagbor H, Antwi GD, Acheampong PR, Bart Plange C, Chandramohan D, Cairns M
Trop Med Int Health 2016 Feb;21(2):224-35. Epub 2015 Dec 16 doi: 10.1111/tmi.12642. PMID: 26578353Free PMC Article
Wragge SE, Toure D, Coetzee M, Gilbert A, Christian R, Segoea G, Hunt RH, Coetzee M
Trans R Soc Trop Med Hyg 2015 Dec;109(12):755-62. doi: 10.1093/trstmh/trv089. PMID: 26626339
Smithson P, Florey L, Salgado SR, Hershey CL, Masanja H, Bhattarai A, Mwita A, McElroy PD; Tanzania Malaria Impact Evaluation Research Group.
PLoS One 2015 Nov 4;10(11):e0141112. doi: 10.1371/journal.pone.0141112. PMID: 26536354Free PMC Article

Clinical prediction guides

Adeola AM, Botai OJ, Olwoch JM, Rautenbach CJ, Adisa OM, Taiwo OJ, Kalumba AM
Trop Med Int Health 2016 May;21(5):675-86. Epub 2016 Mar 3 doi: 10.1111/tmi.12680. PMID: 26914617
Govindasamy G, Barber BE, Ghani SA, William T, Grigg MJ, Borooah S, Dhillon B, Dondorp AM, Yeo TW, Anstey NM, Maude RJ
J Infect Dis 2016 May 1;213(9):1476-82. Epub 2015 Dec 15 doi: 10.1093/infdis/jiv746. PMID: 26671886
Velarde-Rodríguez M, Van den Bergh R, Fergus C, Casellas A, Sanz S, Cibulskis R, Ramsay AR, Bissell K, Zachariah R
Glob Health Action 2015 Oct 7;8:29133. PMID: 26449205Free PMC Article
Ndhlovu M, Nkhama E, Miller JM, Hamer DH
Trop Med Int Health 2015 Dec;20(12):1696-706. Epub 2015 Sep 29 doi: 10.1111/tmi.12591. PMID: 26311240
Kamuliwo M, Kirk KE, Chanda E, Elbadry MA, Lubinda J, Weppelmann TA, Mukonka VM, Zhang W, Mushinge G, Mwanza-Ingwe M, Haque U
Trans R Soc Trop Med Hyg 2015 Aug;109(8):514-21. Epub 2015 Jul 9 doi: 10.1093/trstmh/trv049. PMID: 26160256

Recent systematic reviews

Homan T, Hiscox A, Mweresa CK, Masiga D, Mukabana WR, Oria P, Maire N, Pasquale AD, Silkey M, Alaii J, Bousema T, Leeuwis C, Smith TA, Takken W
Lancet 2016 Sep 17;388(10050):1193-201. Epub 2016 Aug 9 doi: 10.1016/S0140-6736(16)30445-7. PMID: 27520594
Eisele TP, Silumbe K, Finn T, Chalwe V, Kamuliwo M, Hamainza B, Moonga H, Bennett A, Yukich J, Keating J, Steketee RW, Miller JM
Trials 2015 Aug 13;16:347. doi: 10.1186/s13063-015-0862-3. PMID: 26268804Free PMC Article
Kassam R, Collins JB, Liow E, Rasool N
Acta Trop 2015 Dec;152:252-68. Epub 2015 Aug 7 doi: 10.1016/j.actatropica.2015.07.028. PMID: 26257070
Das DK, Mukherjee R, Chakraborty C
J Microsc 2015 Oct;260(1):1-19. Epub 2015 Jun 5 doi: 10.1111/jmi.12270. PMID: 26047029
Van Remoortel H, De Buck E, Singhal M, Vandekerckhove P, Agarwal SP
Trop Med Int Health 2015 Aug;20(8):972-82. Epub 2015 Apr 30 doi: 10.1111/tmi.12522. PMID: 25877758

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