Format
Items per page

Send to:

Choose Destination

Links from PubMed

Items: 1 to 20 of 37

1.

Leukemia

Leukemia is cancer of the white blood cells. White blood cells help your body fight infection. Your blood cells form in your bone marrow. In leukemia, the bone marrow produces abnormal white blood cells. These cells crowd out the healthy blood cells, making it hard for blood to do its work. There are different types of leukemia, including. -Acute lymphocytic leukemia. -Acute myeloid leukemia. -Chronic lymphocytic leukemia. -Chronic myeloid leukemia. Leukemia can develop quickly or slowly. Chronic leukemia grows slowly. In acute leukemia, the cells are very abnormal and their number increases rapidly. Adults can get either type; children with leukemia most often have an acute type. Some leukemias can often be cured. Other types are hard to cure, but you can often control them. Treatments may include chemotherapy, radiation and stem cell transplantation. Even if symptoms disappear, you might need therapy to prevent a relapse. NIH: National Cancer Institute.  [from MedlinePlus]

MedGen UID:
9725
Concept ID:
C0023418
Neoplastic Process
2.

Acute lymphoblastic leukemia

A form of acute leukemia characterized by excess lympoblasts. [from HPO]

MedGen UID:
505958
Concept ID:
CN005851
Finding
3.

Acute

Sudden appearance of disease manifestations over a short period of time. [from HPO]

MedGen UID:
61381
Concept ID:
C0205178
Temporal Concept
4.

Acute lymphoid leukemia

Acute lymphoblastic leukemia (ALL), also known as acute lymphocytic leukemia, is a subtype of acute leukemia, a cancer of the white blood cells. Somatically acquired mutations in several genes have been identified in ALL lymphoblasts, cells in the early stages of differentiation. Germline variation in certain genes may also predispose to susceptibility to ALL (Trevino et al., 2009). Genetic Heterogeneity of Acute Lymphoblastic Leukemia A susceptibility locus for acute lymphoblastic leukemia (ALL1) has been mapped to chromosome 10q21. See also ALL2 (613067), which has been mapped to chromosome 7p12.2; and ALL3 (615545), which is caused by mutation in the PAX5 gene (167414) on chromosome 9p. [from OMIM]

MedGen UID:
7317
Concept ID:
C0023449
Neoplastic Process
5.

B-Cell Leukemia

A malignant disease of the B-LYMPHOCYTES in the bone marrow and/or blood. [from MeSH]

MedGen UID:
412152
Concept ID:
C2004493
Neoplastic Process
6.

Clonal Evolution

The process of accumulation of genetic and epigenetic changes over time in individual cells and the effect of the changes on CELL PROLIFERATION. [from MeSH]

MedGen UID:
273181
Concept ID:
C1516669
Neoplastic Process
7.

Neoplasm

An organ or organ-system abnormality that consists of uncontrolled autonomous cell-proliferation which can occur in any part of the body as a benign or malignant neoplasm (tumour). [from HPO]

MedGen UID:
10294
Concept ID:
C0027651
Neoplastic Process
8.

Neoplasms

MedGen UID:
880980
Concept ID:
CN236628
Disease or Syndrome
9.

Leukemia, acute lymphoblastic, susceptibility to, 3

MedGen UID:
816204
Concept ID:
C3809874
Neoplastic Process
10.

PROGRESSIVE ENCEPHALOMYELITIS WITH RIGIDITY

MedGen UID:
349287
Concept ID:
C1861457
Disease or Syndrome
11.

metaplastic cell transformation

The conversion of a cell from a normal phenotype, which undergoes a limited number of mitotic divisions, into an aberrant phenotype that is immortal and divides indefinitely. Transformed cells no longer retain cell-cycle checkpoints and may ultimately become malignant cancer cells via additional genetic mutations, or damaging environmental events. [from NCI]

MedGen UID:
266929
Concept ID:
C1510411
Pathologic Function
12.

Residual Disease

Cancer cells that remain after attempts to remove the cancer have been made. [from NCI_NCI-GLOSS]

MedGen UID:
108162
Concept ID:
C0543478
Neoplastic Process
13.

Minimal Residual Disease

remainder of a tumor or a neoplasm/cancer after primary, potentially curative therapy. [from CRISP]

MedGen UID:
66115
Concept ID:
C0242596
Neoplastic Process
14.

Clinical finding

clinical manifestations that can be either objective when observed by a physician, or subjective when perceived by the patient. [from CRISP]

MedGen UID:
19974
Concept ID:
C0037088
Sign or Symptom
15.

Recurrence (disease attribute)

The return of a sign, symptom, or disease after a remission. [from MeSH]

MedGen UID:
416712
Concept ID:
C2825055
Pathologic Function
16.

Precursor Cell Lymphoblastic Leukemia-Lymphoma

A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias. [from MeSH]

MedGen UID:
409528
Concept ID:
C1961102
Neoplastic Process
17.

Disease Attributes

Clinical characteristics of disease or illness. [from MeSH]

MedGen UID:
199876
Concept ID:
C0752357
Disease or Syndrome
18.

Lymphatism

MedGen UID:
141817
Concept ID:
C0524631
Disease or Syndrome
19.

Pre-B Acute Lymphoblastic Leukemia

An acute lymphoblastic leukemia that originates from pre-B lymphocytes. The pre-B lymphoblasts contain cytoplasmic immunoglobulin. [from NCI]

MedGen UID:
44126
Concept ID:
C0023485
Neoplastic Process
20.

Leukemia, Lymphocytic, Acute, L1

When the disease process is confined to a mass lesion with no or minimal evidence of blood and less than 25% marrow involvement, the diagnosis is lymphoblastic lymphoma; with blood and greater than 25% marrow involvement, ALL is the appropriate term. [from MeSH]

MedGen UID:
44122
Concept ID:
C0023452
Neoplastic Process
Format
Items per page

Send to:

Choose Destination

Supplemental Content

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center