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Items: 1 to 20 of 44

1.

Levetiracetam

A pyrrolidine with antiepileptic activity. The exact mechanism through which levetiracetam exerts its effects is unknown but does not involve inhibitory and excitatory neurotransmitter activity. Stereoselective binding of levetiracetam was confined to synaptic plasma membranes in the central nervous system with no binding occurring in peripheral tissue. Levetiracetam inhibits burst firing without affecting normal neuronal excitability, which suggests that it may selectively prevent hyper-synchronization of epileptiform burst firing and propagation of seizure activity. [from NCI]

MedGen UID:
87805
Concept ID:
C0377265
Organic Chemical; Pharmacologic Substance
2.

Alzheimer disease

Alzheimer disease (AD) is characterized by dementia that typically begins with subtle and poorly recognized failure of memory and slowly becomes more severe and, eventually, incapacitating. Other common findings include confusion, poor judgment, language disturbance, agitation, withdrawal, and hallucinations. Occasionally, seizures, Parkinsonian features, increased muscle tone, myoclonus, incontinence, and mutism occur. Death usually results from general inanition, malnutrition, and pneumonia. The typical clinical duration of the disease is eight to ten years, with a range from one to 25 years. Approximately 25% of all AD is familial (i.e., =2 persons in a family have AD) of which approximately 95% is late onset (age >60-65 years) and 5% is early onset (age <65 years). [from GTR]

MedGen UID:
1853
Concept ID:
C0002395
Disease or Syndrome
3.

Mental deterioration

Loss of previously present mental abilities, generally in adults. [from HPO]

MedGen UID:
66713
Concept ID:
C0234985
Pathologic Function
4.

Detected

The measurement of the specified component / analyte, organism or clinical sign above the limit of detection of the performed test or procedure.  [from HL7]

MedGen UID:
617726
Concept ID:
C0442726
Finding
5.

Cognitive impairment

Abnormality in the process of thought including the ability to process information. [from HPO]

MedGen UID:
151917
Concept ID:
C0683322
Mental or Behavioral Dysfunction
6.

Chronic

Slow, creeping onset, slow progress and long continuance of disease manifestations. [from HPO]

MedGen UID:
104657
Concept ID:
C0205191
Temporal Concept
7.

Abnormal

Deviating in any way from the state, position, structure, condition, behavior, or rule which is considered a norm. [from NCI]

MedGen UID:
59964
Concept ID:
C0205161
Finding
8.

Neurocognitive disorder

A disorder characterised by a decline primarily in intellectual function due to disease of the brain caused by a variety of acquired conditions such as cerebrovascular disease, Alzheimer's disease, infections, adverse drug reactions and trauma. [from SNOMEDCT_US]

MedGen UID:
873945
Concept ID:
C4041080
Mental or Behavioral Dysfunction
9.

Geram

MedGen UID:
327666
Concept ID:
C1564010
Organic Chemical; Pharmacologic Substance
10.

Axonyl

MedGen UID:
327665
Concept ID:
C1564003
Organic Chemical; Pharmacologic Substance
11.

Sinapsan

MedGen UID:
289715
Concept ID:
C1564013
Organic Chemical; Pharmacologic Substance
12.

Memo-Puren

MedGen UID:
289714
Concept ID:
C1564011
Organic Chemical; Pharmacologic Substance
13.

Dinagen

MedGen UID:
289713
Concept ID:
C1564009
Organic Chemical; Pharmacologic Substance
14.

Avigilen

MedGen UID:
289712
Concept ID:
C1564002
Organic Chemical; Pharmacologic Substance
15.

Piracetrop

MedGen UID:
288864
Concept ID:
C1564014
Organic Chemical; Pharmacologic Substance
16.

Piracebral

MedGen UID:
288863
Concept ID:
C1564012
Organic Chemical; Pharmacologic Substance
17.

Gabacet

MedGen UID:
288862
Concept ID:
C1564008
Organic Chemical; Pharmacologic Substance
18.

Cuxabrain

MedGen UID:
288861
Concept ID:
C1564007
Organic Chemical; Pharmacologic Substance
19.

Ciclofalina

MedGen UID:
288860
Concept ID:
C1564006
Organic Chemical; Pharmacologic Substance
20.

Cerebroforte

MedGen UID:
288858
Concept ID:
C1564004
Organic Chemical; Pharmacologic Substance
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