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Bismuth subsalicylate

MedGen UID:
15063
Concept ID:
C0053792
Organic Chemical; Pharmacologic Substance
Synonyms: bismuth subsalicylate; subsalicylate bismuth
SNOMED CT: Bismuth subsalicylate (82075003); Bismuth subsalicylate (409307004)
 

Definition

A bismuth salt of salicylic acid. Little absorbed from the gastrointestinal tract, bismuth subsalicylate exerts a local effect on the gastric mucosa, coating it and protecting it from the corrosive effects of acid and pepsin. This agent also has local antimicrobial properties. (NCI04) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBismuth subsalicylate

Recent clinical studies

Etiology

Kafil TS, Nguyen TM, Patton PH, MacDonald JK, Chande N, McDonald JW
Cochrane Database Syst Rev 2017 Nov 11;11:CD003575. doi: 10.1002/14651858.CD003575.pub6. PMID: 29127772
Chowdhury HR, Yunus M, Zaman K, Rahman A, Faruque SM, Lescano AG, Sack RB
Acta Paediatr 2001 Jun;90(6):605-10. PMID: 11440090
Bagchi D, McGinn TR, Ye X, Balmoori J, Bagchi M, Stohs SJ, Kuszynski CA, Carryl OR, Mitra S
Dig Dis Sci 1999 Dec;44(12):2419-28. PMID: 10630491
Fine KD, Lee EL
Gastroenterology 1998 Jan;114(1):29-36. PMID: 9428215
DuPont HL, Ericsson CD, Johnson PC, Bitsura JA, DuPont MW, de la Cabada FJ
JAMA 1987 Mar 13;257(10):1347-50. PMID: 3820443

Diagnosis

Colussi D, Salari B, Stewart KO, Lauwers GY, Richter JR, Chan AT, Ricciardiello L, Khalili H
Scand J Gastroenterol 2015;50(11):1382-8. Epub 2015 May 21 doi: 10.3109/00365521.2015.1050692. PMID: 25997458Free PMC Article
Yakoob J, Abbas Z, Usman MW, Awan S, Naz S, Jafri F, Hamid S, Jafri W
Microb Drug Resist 2014 Aug;20(4):305-9. Epub 2013 Jul 11 doi: 10.1089/mdr.2013.0086. PMID: 23844851
Graham DY, Hoffman J, el-Zimaity HM, Graham DP, Osato M
Aliment Pharmacol Ther 1997 Oct;11(5):935-8. PMID: 9354203
Butcher GP, Ryder SD, Hughes SJ, Stewart M, Bird N, Haqqani MT, Rhodes JM
Digestion 1992;53(3-4):142-8. doi: 10.1159/000200989. PMID: 1291402
Eberhardt R, Kasper G
Rev Infect Dis 1990 Jan-Feb;12 Suppl 1:S115-9. PMID: 2406852

Therapy

Sheele J, Cartowski J, Dart A, Poddar A, Gupta S, Stashko E, Ravi BS, Nelson C, Gupta A
Pathog Glob Health 2015 Sep;109(6):275-82. Epub 2015 Aug 11 doi: 10.1179/2047773215Y.0000000028. PMID: 26260354Free PMC Article
Bingham AL, Brown RO, Dickerson RN
Nutr Clin Pract 2013 Dec;28(6):766-9. Epub 2013 Oct 25 doi: 10.1177/0884533613507606. PMID: 24163322
Cohen PR
J Drugs Dermatol 2009 Dec;8(12):1132-5. PMID: 20027942
Dy RM, Lof J, DiBaise JK, Quigley EM
Dig Dis Sci 1999 Feb;44(2):286-9. PMID: 10063913
Healy DP, Dansereau RJ, Dunn AB, Clendening CE, Mounts AW, Deepe GS Jr
Ann Pharmacother 1997 Dec;31(12):1460-4. doi: 10.1177/106002809703101203. PMID: 9416381

Prognosis

Colussi D, Salari B, Stewart KO, Lauwers GY, Richter JR, Chan AT, Ricciardiello L, Khalili H
Scand J Gastroenterol 2015;50(11):1382-8. Epub 2015 May 21 doi: 10.3109/00365521.2015.1050692. PMID: 25997458Free PMC Article
Chowdhury HR, Yunus M, Zaman K, Rahman A, Faruque SM, Lescano AG, Sack RB
Acta Paediatr 2001 Jun;90(6):605-10. PMID: 11440090
Fine KD, Lee EL
Gastroenterology 1998 Jan;114(1):29-36. PMID: 9428215
Chey WD, Fisher L, Elta GH, Barnett JL, Nostrant T, DelValle J, Hasler WL, Scheiman JM
Am J Gastroenterol 1997 Sep;92(9):1483-6. PMID: 9317068
Wagner S, Gebel M, Haruma K, Bär W, Lange P, Freise J, Gladziwa U, Schmidt FW
Gut 1992 Feb;33(2):179-83. PMID: 1347278Free PMC Article

Clinical prediction guides

Bingham AL, Brown RO, Dickerson RN
Nutr Clin Pract 2013 Dec;28(6):766-9. Epub 2013 Oct 25 doi: 10.1177/0884533613507606. PMID: 24163322
Cohen PR
J Drugs Dermatol 2009 Dec;8(12):1132-5. PMID: 20027942
Bagchi D, McGinn TR, Ye X, Balmoori J, Bagchi M, Stohs SJ, Kuszynski CA, Carryl OR, Mitra S
Dig Dis Sci 1999 Dec;44(12):2419-28. PMID: 10630491
Healy DP, Dansereau RJ, Dunn AB, Clendening CE, Mounts AW, Deepe GS Jr
Ann Pharmacother 1997 Dec;31(12):1460-4. doi: 10.1177/106002809703101203. PMID: 9416381
Chey WD, Fisher L, Elta GH, Barnett JL, Nostrant T, DelValle J, Hasler WL, Scheiman JM
Am J Gastroenterol 1997 Sep;92(9):1483-6. PMID: 9317068

Recent systematic reviews

Kafil TS, Nguyen TM, Patton PH, MacDonald JK, Chande N, McDonald JW
Cochrane Database Syst Rev 2017 Nov 11;11:CD003575. doi: 10.1002/14651858.CD003575.pub6. PMID: 29127772
Goldman RD
Can Fam Physician 2013 Aug;59(8):843-4. PMID: 23946025Free PMC Article
Chande N, McDonald JW, Macdonald JK
Cochrane Database Syst Rev 2008 Apr 16;(2):CD006096. doi: 10.1002/14651858.CD006096.pub3. PMID: 18425936
Chande N, McDonald JW, Macdonald JK
Cochrane Database Syst Rev 2008 Apr 16;(2):CD003575. doi: 10.1002/14651858.CD003575.pub5. PMID: 18425892
Chande N, McDonald JW, Macdonald JK
Cochrane Database Syst Rev 2007 Jan 24;(1):CD006096. doi: 10.1002/14651858.CD006096.pub2. PMID: 17253579

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