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Items: 9

1.

Amikacin

A broad-spectrum antibiotic derived from KANAMYCIN. It is reno- and oto-toxic like the other aminoglycoside antibiotics. [from MeSH]

MedGen UID:
1863
Concept ID:
C0002499
Antibiotic; Organic Chemical
2.

Indicated

MedGen UID:
731837
Concept ID:
C1444656
Finding
3.

Quinone

MedGen UID:
203341
Concept ID:
C1096793
Organic Chemical; Pharmacologic Substance
4.

Vitamin K>2<

A group of substances similar to VITAMIN K 1 which contains a ring of 2-methyl-1,4-naphthoquinione and an isoprenoid side chain of varying number of isoprene units. In vitamin K 2, each isoprene unit contains a double bond. They are produced by bacteria including the normal intestinal flora. [from MeSH]

MedGen UID:
39473
Concept ID:
C0086605
Organic Chemical; Pharmacologic Substance; Vitamin
5.

Naphthalene

A white, volatile, solid polycyclic hydrocarbon with a strong mothball odor. Naphthalene is obtained from either coal tar or petroleum distillation and is primarily used to manufacture phthalic anhydride, but is also used in moth repellents. Exposure to naphthalene is associated with hemolytic anemia, damage to the liver and neurological system, cataracts and retinal hemorrhage. Naphthalene is reasonably anticipated to be a human carcinogen and may be associated with an increased risk of developing laryngeal and colorectal cancer. (NCI05) [from NCI]

MedGen UID:
10178
Concept ID:
C0027375
Organic Chemical; Pharmacologic Substance
6.

Kanamycin

An aminoglycoside antibiotic with antimicrobial property. Amikacin irreversibly binds to the bacterial 30S ribosomal subunit, specifically in contact with 16S rRNA and S12 protein within the 30S subunit. This leads to interference with translational initiation complex and, misreading of mRNA, thereby hampering protein synthesis and resulting in bactericidal effect. This agent is usually used for treatment of E. coli, Proteus species (both indole-positive and indole-negative), E. aerogenes, K. pneumoniae, S. marcescens, and Acinetobacter species. [from NCI]

MedGen UID:
7193
Concept ID:
C0022487
Antibiotic; Organic Chemical
7.

Aminoglycosides

Glycosylated compounds in which there is an amino substituent on the glycoside. Some of them are clinically important ANTIBIOTICS. [from MeSH]

MedGen UID:
257
Concept ID:
C0002556
Organic Chemical; Pharmacologic Substance
8.

Disorder of vitamin K

MedGen UID:
696124
Concept ID:
C1272561
Disease or Syndrome
9.

Disorder of vitamin K2

MedGen UID:
695927
Concept ID:
C1272354
Disease or Syndrome
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