Format
Items per page

Send to:

Choose Destination

Links from PubMed

Items: 16

1.

Tocilizumab

A recombinant, humanized IgG1 monoclonal antibody directed against the interleukin-6 receptor (IL-6R) with immunosuppressant activity. Tocilizumab targets and binds to both the soluble form of IL-6R (sIL-6R) and the membrane-bound form (mIL-6R), thereby blocking the binding of IL-6 to its receptor. This prevents IL-6-mediated signaling. Il-6, a pro-inflammatory cytokine that plays an important role in the regulation of the immune response, is overproduced in autoimmune disorders and certain types of cancers. [from NCI]

MedGen UID:
299170
Concept ID:
C1609165
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
2.

Vessel (polysaccharide)

MedGen UID:
56099
Concept ID:
C0148346
Organic Chemical; Pharmacologic Substance
3.

Giant cell arteritis

A systemic autoimmune disorder that typically affects medium and large ARTERIES, usually leading to occlusive granulomatous vasculitis with transmural infiltrate containing multinucleated GIANT CELLS. The TEMPORAL ARTERY is commonly involved. This disorder appears primarily in people over the age of 50. Symptoms include FEVER; FATIGUE; HEADACHE; visual impairment; pain in the jaw and tongue; and aggravation of pain by cold temperatures. (From Adams et al., Principles of Neurology, 6th ed) [from MeSH]

MedGen UID:
21478
Concept ID:
C0039483
Disease or Syndrome
4.

Takayasu arteritis

A chronic inflammatory process that affects the AORTA and its primary branches, such as the brachiocephalic artery (BRACHIOCEPHALIC TRUNK) and CAROTID ARTERIES. It results in progressive arterial stenosis, occlusion, and aneurysm formation. The pulse in the arm is hard to detect. Patients with aortitis syndrome often exhibit retinopathy. [from MeSH]

MedGen UID:
21458
Concept ID:
C0039263
Disease or Syndrome
5.

Polymyalgia rheumatica

A syndrome characterized by pain, stiffness, and tenderness of the proximal muscle groups including the shoulder, pelvic girdle and the neck. There is no muscle atrophy and muscle biopsies do not reveal pathologic changes. Additional signs and symptoms include low grade fever, fatigue and depression. [from NCI]

MedGen UID:
19393
Concept ID:
C0032533
Disease or Syndrome
6.

Arteritis

An inflammatory process affecting an artery. [from NCI]

MedGen UID:
13916
Concept ID:
C0003860
Pathologic Function
7.

Vasculitis

An inflammatory process involving the wall of the vessels (large, medium, or small-sized vessels). The inflammatory process may cause necrosis or formation of granulomas in the vascular wall. It may be the result of an autoimmune disorder, infection, or malignancy. Representative examples include polyarteritis nodosa, temporal arteritis, Wegener granulomatosis, Kawasaki disease, Takayasu arteritis, and Henoch-Schonlein purpura. [from NCI]

MedGen UID:
12054
Concept ID:
C0042384
Disease or Syndrome
8.

Large vessel vasculitis

A type of vasculitis (inflammation of blood vessel walls) affecting large arteries such as the aorta and branches of the aorta. [from HPO]

MedGen UID:
870761
Concept ID:
C4025218
Disease or Syndrome
9.

Vasculitis

Vasculitis represents a clinically heterogenous group of diseases of multifactorial etiology characterized by inflammation of either large-sized vessels (large-vessel vasculitis, e.g. Giant-cell arteritis and Takayasu arteritis; see these terms), medium-sized vessels (medium-vessel vasculitis e.g. polyarteritis nodosa and Kawasaki disease; see these terms), or small-sized vessels (small-vessel vasculitis, e.g. granulomatosis with polyangiitis, microscopic polyangiitis, immunoglobulin A vasculitis, and cutaneous leukocytoclastic angiitis; see these terms). Vasculitis occurs at any age, may be acute or chronic, and manifests with general symptoms such as fever, weight loss and fatigue, as well as more specific clinical signs depending on the type of vessels and organs affected. The degree of severity is variable, ranging from life or sight threatening disease (e.g. Behçet disease, see this term) to relatively minor skin disease. [from ORDO]

MedGen UID:
833235
Concept ID:
CN229172
Finding
10.

Polymyalgia

MedGen UID:
636636
Concept ID:
C0521516
Sign or Symptom
11.

Large vessel vasculitis

A type of vasculitis (inflammation of blood vessel walls) affecting large arteries such as the aorta and branches of the aorta. [from HPO]

MedGen UID:
505792
Concept ID:
CN004711
Finding
12.

Temporal arteritis

An autoimmune, systemic, giant cell granulomatous arteritis predominantly involving the arteries that supply blood to the central nervous system, head and eyes. Superficial arteries of the scalp that are involved tend to be enlarged and tender. Signs and symptoms include headaches, myalgias, visual disturbances, and skin necrosis. [from NCI]

MedGen UID:
365495
Concept ID:
C1956391
Disease or Syndrome
13.

Rhizomelic pseudopolyarthritis

MedGen UID:
315956
Concept ID:
C1527406
Disease or Syndrome
14.

transaminitis

MedGen UID:
852409
Concept ID:
C1096646
15.

Transaminitis

Abnormally high levels of alanine transaminase (ALT) and/or aspartate transaminase (AST) in the blood. [from NCI]

MedGen UID:
810998
Concept ID:
C2242708
Finding
16.

Postoperative myocardial infarction

MedGen UID:
670509
Concept ID:
C0589368
Disease or Syndrome
Format
Items per page

Send to:

Choose Destination

Supplemental Content

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center