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Items: 15

1.

Sick sinus syndrome

A condition caused by dysfunctions related to the SINOATRIAL NODE including impulse generation (CARDIAC SINUS ARREST) and impulse conduction (SINOATRIAL EXIT BLOCK). It is characterized by persistent BRADYCARDIA, chronic ATRIAL FIBRILLATION, and failure to resume sinus rhythm following CARDIOVERSION. This syndrome can be congenital or acquired, particularly after surgical correction for heart defects. [from MeSH]

MedGen UID:
20749
Concept ID:
C0037052
Disease or Syndrome
2.

Syndrome

A characteristic symptom complex. [from MeSH]

MedGen UID:
11688
Concept ID:
C0039082
Disease or Syndrome
3.

Cardiac arrhythmia

A disorder in which there is abnormal electrical activity in the heart. [from SNOMEDCT_US]

MedGen UID:
2039
Concept ID:
C0003811
Finding; Finding
4.

Aging

Progressive damage to mitochondrial DNA (mtDNA) during life is thought to contribute to aging processes. This notion is supported by the observation of an aging-related accumulation in human mtDNA of oxidative and alkylation derivatives of nucleotides, of small deletions and insertions, and of large deletions, although their low frequency raises questions about their functional significance (Michikawa et al., 1999). [from GTR]

MedGen UID:
1376
Concept ID:
C0001811
Organism Function
5.

Sinus arrhythmia

An electrocardiographic finding in which the sinus rate fluctuates with the respiratory cycle. (CDISC) [from NCI]

MedGen UID:
398
Concept ID:
C0003813
Finding
6.

Spastic paraplegia, intellectual disability, nystagmus, and obesity

Spastic paraplegia, intellectual disability, nystagmus, and obesity (SINO) is an autosomal dominant neurologic disorder characterized by rapid growth in infancy, global developmental delay, spastic paraplegia, variable ophthalmologic defects, and dysmorphic facial features (summary by Josifova et al., 2016). [from GTR]

MedGen UID:
924883
Concept ID:
C4284592
Disease or Syndrome
7.

Borries syndrome

MedGen UID:
542920
Concept ID:
C0270677
Disease or Syndrome
8.

Sick sinus syndrome

MedGen UID:
409588
Concept ID:
C1963235
Finding
9.

Hypoparathyroidism retardation dysmorphism syndrome

HRDS is an autosomal recessive multisystem disorder characterized by intrauterine and postnatal growth retardation, infantile-onset hypoparathyroidism that can result in severe hypocalcemic seizures, dysmorphic facial features, and developmental delay (summary by Padidela et al., 2009 and Ratbi et al., 2015). [from GTR]

MedGen UID:
340984
Concept ID:
C1855840
Disease or Syndrome
10.

Sinus

Abnormal communication most commonly seen between two internal organs, or between an internal organ and the surface of the body. [from MeSH]

MedGen UID:
5201
Concept ID:
C0016169
Anatomical Abnormality
11.

Heart disease

A non-neoplastic or neoplastic disorder that affects the heart and/or the pericardium. Representative examples include endocarditis, pericarditis, atrial myxoma, cardiac myeloid sarcoma, and pericardial malignant mesothelioma. [from NCI]

MedGen UID:
5458
Concept ID:
C0018799
Disease or Syndrome
12.

Disorder of cardiovascular system

A non-neoplastic or neoplastic disorder affecting the heart or the vessels (arteries, veins and lymph vessels). Representative examples of non-neoplastic cardiovascular disorders are endocarditis and hypertension. Representative examples of neoplastic cardiovascular disorders are endocardial myxoma and angiosarcoma. [from NCI]

MedGen UID:
2848
Concept ID:
C0007222
Disease or Syndrome
13.

Cardiac pacemaker battery malfunction

MedGen UID:
873440
Concept ID:
C4040575
Pathologic Function
14.

Cardiac pacemaker syndrome

MedGen UID:
574067
Concept ID:
C0340929
Pathologic Function
15.

Malfunction from artificial pacing

MedGen UID:
534348
Concept ID:
C0232196
Pathologic Function
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