Format
Items per page

Send to:

Choose Destination

Links from PubMed

Items: 7

1.

Rituximab

A murine-derived monoclonal antibody and ANTINEOPLASTIC AGENT that binds specifically to the CD20 ANTIGEN and is used in the treatment of LEUKEMIA; LYMPHOMA and RHEUMATOID ARTHRITIS. [from MeSH]

MedGen UID:
95963
Concept ID:
C0393022
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
2.

Thrombocytopenia

A laboratory test result indicating that there is an abnormally small number of platelets in the circulating blood. [from NCI]

MedGen UID:
52737
Concept ID:
C0040034
Disease or Syndrome
3.

Autoimmune thrombocytopenia

An autoimmune coagulation disorder characterized by isolated thrombocytopenia (a platelet count <100,000/microL), in the absence of any underlying disorder that may be associated with thrombocytopenia. [from SNOMEDCT_US]

MedGen UID:
584986
Concept ID:
C0398650
Disease or Syndrome
4.

Thrombocytopenia

MedGen UID:
472158
Concept ID:
CN130080
Disease or Syndrome
5.

Autoimmune thrombocytopenia

The presence of thrombocytopenia in combination with detection of antiplatelet antibodies. [from HPO]

MedGen UID:
75778
Concept ID:
C0272286
Disease or Syndrome
6.

Autoimmune lymphoproliferative syndrome, type 2

Autoimmune lymphoproliferative syndrome (ALPS), caused by defective lymphocyte homeostasis, is characterized by the following: Non-malignant lymphoproliferation (lymphadenopathy, hepatosplenomegaly with or without hypersplenism) that often improves with age. Autoimmune disease, mostly directed toward blood cells. Lifelong increased risk for both Hodgkin and non-Hodgkin lymphoma. In ALPS-FAS (the most common and best-characterized type of ALPS, associated with heterozygous germline pathogenic variants in FAS), non-malignant lymphoproliferation typically manifests in the first years of life, inexplicably waxes and wanes, and then often decreases without treatment in the second decade of life; in many affected individuals, however, neither splenomegaly nor the overall expansion of lymphocyte subsets in peripheral blood decreases. Although autoimmunity is often not present at the time of diagnosis or at the time of the most extensive lymphoproliferation, autoantibodies can be detected before autoimmune disease manifests clinically. In ALPS-FAS caused by homozygous or compound heterozygous (biallelic) pathogenic variants in FAS, severe lymphoproliferation occurs before, at, or shortly after birth, and usually results in death at an early age. ALPS-sFAS, resulting from somatic FAS pathogenic variants in selected cell populations, notably the alpha/beta double-negative T cells (a/ß-DNT cells), appears to be similar to ALPS-FAS resulting from heterozygous germline pathogenic variants in FAS, although lower incidence of splenectomy and lower lymphocyte counts have been reported in ALPS-sFAS and no cases of lymphoma have yet been published. [from GTR]

MedGen UID:
349065
Concept ID:
C1858968
Disease or Syndrome
7.

Evans syndrome

A rare, chronic and relapsing autoimmune disorder of unknown etiology, characterized by the presence of immune thrombocytopenia and autoimmune hemolytic anemia. [from NCI]

MedGen UID:
75773
Concept ID:
C0272126
Disease or Syndrome
Format
Items per page

Send to:

Choose Destination

Supplemental Content

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center