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Items: 5

1.

Glomus Tumor

A rare benign or malignant mesenchymal neoplasm arising from cells that resemble the modified smooth muscle cells of the glomus body. The majority of glomus tumors occur in the distal extremities. [from NCI]

MedGen UID:
4903
Concept ID:
C0017653
Neoplastic Process
2.

Gastric Glomus Tumor

A rare glomus tumor that arises from the stomach. It is seen in adults, especially women. The majority of cases follow a benign clinical course. [from NCI]

MedGen UID:
474057
Concept ID:
C3272424
Neoplastic Process
3.

Paragangliomas 1

Hereditary paraganglioma-pheochromocytoma (PGL/PCC) syndromes are characterized by paragangliomas (tumors that arise from neuroendocrine tissues symmetrically distributed along the paravertebral axis from the base of the skull to the pelvis) and by pheochromocytomas (paragangliomas that are confined to the adrenal medulla). Sympathetic paragangliomas hypersecrete catecholamines; parasympathetic paragangliomas are most often nonsecretory. Extra-adrenal parasympathetic paragangliomas are located predominantly in the skull base, neck, and upper medistinum; approximately 95% of such tumors are nonsecretory. In contrast, sympathetic extra-adrenal paragangliomas are generally confined to the lower mediastinum, abdomen, and pelvis, and are typically secretory. Pheochromocytomas, which arise from the adrenal medulla, typically hypersecrete catecholamines. Symptoms of PGL/PCC result either from mass effects or catecholamine hypersecretion (e.g., sustained or paroxysmal elevations in blood pressure, headache, episodic profuse sweating, forceful palpitations, pallor, and apprehension or anxiety). The risk for malignant transformation is greater for extra-adrenal sympathetic paragangliomas than for pheochromocytomas or skull base and neck paragangliomas. [from GeneReviews]

MedGen UID:
358258
Concept ID:
C1868633
Disease or Syndrome
4.

Neoplasm

MedGen UID:
227011
Concept ID:
C1306459
Neoplastic Process
5.

Neoplasm

MedGen UID:
10294
Concept ID:
C0027651
Neoplastic Process
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