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Items: 1 to 20 of 24

1.

Hydrocortisone

The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions. [from MeSH]

MedGen UID:
9337
Concept ID:
C0020268
Hormone; Organic Chemical; Pharmacologic Substance
2.

Chromosomal translocation

Any type of genetic recombination involving exchange of DNA between non-homologous chromosomes, which often occurs as the result of non-homologous end-joining of broken DNA strands. Chromosomal translocation is involved in repairing broken DNA and in maintaining cell viability at the expense of long term genomic stability. This process is is associated with particular types of leukemia, infertility and Down Syndrome. [from NCI]

MedGen UID:
21243
Concept ID:
C0040715
Cell or Molecular Dysfunction
3.

Opiate agonist

A class of synthetic chemicals/drugs similar to opiates (opium derivatives) with analgesic properties. Due to binding to opiate receptors, opioids mimic opiate activity on neurons, various cells (i.e. lymphocytes), pain suppression and other neurobehavioral activity. (NCI) [from NCI]

MedGen UID:
66892
Concept ID:
C0242402
Hazardous or Poisonous Substance; Organic Chemical; Pharmacologic Substance
4.

Naloxon-ratiopharm

MedGen UID:
260630
Concept ID:
C1449884
Organic Chemical; Pharmacologic Substance
5.

Nalone

MedGen UID:
258584
Concept ID:
C1449882
Organic Chemical; Pharmacologic Substance
6.

Cortril

MedGen UID:
152044
Concept ID:
C0699402
Hormone; Organic Chemical; Pharmacologic Substance
7.

Cortifair

MedGen UID:
152043
Concept ID:
C0699401
Hormone; Organic Chemical; Pharmacologic Substance
8.

MRZ-2593

MedGen UID:
149072
Concept ID:
C0729156
Organic Chemical; Pharmacologic Substance
9.

Narcan

MedGen UID:
146883
Concept ID:
C0684237
Organic Chemical; Pharmacologic Substance
10.

Sensory System Agents

Drugs that act on neuronal sensory receptors resulting in an increase, decrease, or modification of afferent nerve activity. (From Smith and Reynard, Textbook of Pharmacology, 1991, p367) [from MeSH]

MedGen UID:
67054
Concept ID:
C0243058
Pharmacologic Substance
11.

Peripheral Nervous System Agents

Drugs that act principally at one or more sites within the peripheral neuroeffector systems, the autonomic system, and motor nerve-skeletal system. (From Smith and Reynard, Textbook of Pharmacology, 1991, p75) [from MeSH]

MedGen UID:
67048
Concept ID:
C0243049
Pharmacologic Substance
12.

Opiate Alkaloids

broad family of plant alkaloids with narcotic effects; historically used as sedatives, anesthetics, analgesics, and euphoriants; heroin and morphine are highly addictive, abused drugs. [from CRISP]

MedGen UID:
66385
Concept ID:
C0221793
Organic Chemical; Pharmacologic Substance
13.

Phenanthrenes

MedGen UID:
10693
Concept ID:
C0031368
Organic Chemical; Pharmacologic Substance
14.

Alkaloid

organic nitrogenous bases; many alkaloids of medical importance occur in the animal and vegetable kingdoms. [from CRISP]

MedGen UID:
7968
Concept ID:
C0002062
Organic Chemical; Pharmacologic Substance
15.

Hormones, Hormone Substitutes, and Hormone Antagonists

A collective grouping for both naturally occurring and synthetic hormones, substitutes, and antagonists. [from MeSH]

MedGen UID:
6887
Concept ID:
C0019934
Pharmacologic Substance
16.

Narcotic Antagonists

Any agent that binds to or interferes with binding to any of the opioid receptor subtypes, thereby blocking the actions of opioid agonists. [from NCI]

MedGen UID:
6521
Concept ID:
C0027410
Pharmacologic Substance
17.

Adrenal Cortex Hormones

Any steroid hormone made in the adrenal cortex (the outer part of the adrenal gland). They are also made in the laboratory. Corticosteroids have many different effects in the body, and are used to treat many different conditions. They may be used as hormone replacement, to suppress the immune system, and to treat some side effects of cancer and its treatment. Corticosteroids are also used to treat certain lymphomas and lymphoid leukemias. [from NCI_NCI-GLOSS]

MedGen UID:
1767
Concept ID:
C0001617
Hormone; Organic Chemical; Pharmacologic Substance
18.

Central Nervous System Agents

A class of drugs producing both physiological and psychological effects through a variety of mechanisms. They can be divided into "specific" agents, e.g., affecting an identifiable molecular mechanism unique to target cells bearing receptors for that agent, and "nonspecific" agents, those producing effects on different target cells and acting by diverse molecular mechanisms. Those with nonspecific mechanisms are generally further classed according to whether they produce behavioral depression or stimulation. Those with specific mechanisms are classed by locus of action or specific therapeutic use. (From Gilman AG, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p252) [from MeSH]

MedGen UID:
836
Concept ID:
C0007680
Pharmacologic Substance
19.

Naloxone Abello

MedGen UID:
260631
Concept ID:
C1449885
Organic Chemical; Pharmacologic Substance
20.

Naloxon Curamed

MedGen UID:
260629
Concept ID:
C1449883
Organic Chemical; Pharmacologic Substance
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