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Items: 1 to 20 of 34

1.

Venlafaxine

A synthetic phenethylamine bicyclic derivative with antidepressant activity. Venlafaxine and its active metabolite, O-desmethylvenlafaxine (ODV), are potent inhibitors of neuronal serotonin and norepinephrine reuptake and weak dopamine reuptake inhibitors. This agent may reduce hormone-related vasomotor symptoms. (NCI04) [from NCI]

MedGen UID:
36191
Concept ID:
C0078569
Organic Chemical; Pharmacologic Substance
2.

Catechol

A chemical originally isolated from a type of mimosa tree. Catechol is used as an astringent, an antiseptic, and in photography, electroplating, and making other chemicals. It can also be man-made. [from NCI_NCI-GLOSS]

MedGen UID:
27059
Concept ID:
C0054858
Organic Chemical; Pharmacologic Substance
3.

Anxiety

Apprehension of danger and dread accompanied by restlessness, tension, tachycardia, and dyspnea unattached to a clearly identifiable stimulus. [from NCI]

MedGen UID:
1613
Concept ID:
C0003467
Finding; Finding
4.

Generalized anxiety disorder

An anxiety disorder characterized by excessive and difficult-to-control worry about a number of life situations. The worry is accompanied by restlessness, fatigue, inability to concentrate, irritability, muscle tension, and/or sleep disturbance and lasts for at least 6 months. [from NCI]

MedGen UID:
452363
Concept ID:
C0270549
Mental or Behavioral Dysfunction
5.

Anxiety

Human personality is shaped by genetic and environmental factors, and evidence suggests that the genetic component is highly complex, polygenic, and epistatic. Genetic factors are thought to contribute to 40 to 60% of trait variance. Molecular genetics has tried to identify specific genes for quantitative traits, called quantitative trait loci (QTLs). The QTL concept suggests that complex personality traits or dimensions are not attributable to single genes, but to multiple interacting genes (Reif and Lesch, 2003). Fullerton et al. (2003) stated that psychologists were in agreement that the wide variation in human personalities can be explained by a small number of personality factors, including neuroticism (a measure of emotional stability), which manifests at one extreme as anxiety, depression, moodiness, low self-esteem, and diffidence. They cited a number of studies that had described a relationship between high scores on measures of neuroticism and major depressive disorder. They also noted that theoretical studies had suggested that large samples of randomly ascertained sibs could be used to ascertain phenotypically extreme individuals and thereby increase power to detect genetic linkage in complex traits. See also panic disorder (PAND1; 167870), which is a subtype of anxiety disorder. [from GTR]

MedGen UID:
335849
Concept ID:
C1842981
Mental or Behavioral Dysfunction
6.

Generalized

Affecting all regions without specificity of distribution. [from HPO]

MedGen UID:
104661
Concept ID:
C0205246
Spatial Concept
7.

Anxiety disorder

A category of psychiatric disorders which are characterized by anxious feelings or fear often accompanied by physical symptoms associated with anxiety. [from NCI]

MedGen UID:
361
Concept ID:
C0003469
Mental or Behavioral Dysfunction
8.

Depression

A condition characterized by pervasive dysphoric mood, loss of interests, and inability to experience pleasure. [from HPO]

MedGen UID:
4229
Concept ID:
C0011581
Mental or Behavioral Dysfunction
9.

Depressive Disorder

MedGen UID:
881121
Concept ID:
CN236658
Disease or Syndrome
10.

Mal de debarquement syndrome

MedGen UID:
345629
Concept ID:
C1608983
Disease or Syndrome
11.

Major depressive disorder

Marked depression appearing in the involution period and characterized by hallucinations, delusions, paranoia, and agitation. [from MeSH]

MedGen UID:
266123
Concept ID:
C1269683
Mental or Behavioral Dysfunction
12.

Possible

Capable of happening or occurring. [from NCI]

MedGen UID:
137646
Concept ID:
C0332149
Finding
13.

Examined for

Having been subjected to inspection or evaluation. [from NCI]

MedGen UID:
83047
Concept ID:
C0332128
Finding
14.

Antidepressant

A pharmacological agent that acts on neurotransmitter signaling pathways to alleviate the symptoms of depression. [from NCI]

MedGen UID:
1588
Concept ID:
C0003289
Pharmacologic Substance
15.

Hypervigilance

Condition of elevated sensory sensitivity, perception of risk of threats, and low threshhold for stimuli. [from MeSH]

MedGen UID:
452297
Concept ID:
C0235013
Mental or Behavioral Dysfunction
16.

Sila-Venlafaxine

MedGen UID:
354594
Concept ID:
C1721158
Organic Chemical; Pharmacologic Substance
17.

Dobupal

MedGen UID:
280105
Concept ID:
C1529224
Organic Chemical; Pharmacologic Substance
18.

Venlafaxine hydrochloride

A cyclohexanol and phenylethylamine derivative that functions as a SEROTONIN AND NORADRENALINE REUPTAKE INHIBITOR (SNRI) and is used as an ANTIDEPRESSIVE AGENT. [from MeSH]

MedGen UID:
162695
Concept ID:
C0771200
Organic Chemical; Pharmacologic Substance
19.

Effexor

a kind of depression treatment drug [from CHV]

MedGen UID:
108494
Concept ID:
C0591437
Organic Chemical; Pharmacologic Substance
20.

Antidepressive Agents, Second-Generation

A structurally and mechanistically diverse group of drugs that are not tricyclics or monoamine oxidase inhibitors. The most clinically important appear to act selectively on serotonergic systems, especially by inhibiting serotonin reuptake. [from MeSH]

MedGen UID:
66178
Concept ID:
C0242905
Pharmacologic Substance
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