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Items: 20

1.

Hypertrophy

Cell size enlargement due to the increase in the amount of cytoplasm and its constituent organelles. The cells are larger but otherwise the appearance is unchanged. [from NCI_CDISC]

MedGen UID:
5703
Concept ID:
C0020564
Pathologic Function
2.

Muscle fiber hypertrophy

MedGen UID:
451038
Concept ID:
C0333759
Finding; Finding
3.

Inhibition

MedGen UID:
5809
Concept ID:
C0021469
Molecular Function
4.

Metabolic induction

The conversion of an exogenous substance by a biological system resulting in the production on an active metabolite. [from MeSH]

MedGen UID:
7561
Concept ID:
C0025513
Molecular Function
5.

Skeletal muscle atrophy

The presence of skeletal muscular atrophy (which is also known as amyotrophy). [from HPO]

MedGen UID:
902598
Concept ID:
C0234958
Disease or Syndrome
6.

Negative

An absence finding of the specified component / analyte, organism or clinical sign based on the established threshold of the performed test or procedure. [Note: Negative does not necessarily imply the complete absence of the specified item.].  [from HL7]

MedGen UID:
61377
Concept ID:
C0205160
Finding
7.

Neuromuscular Manifestations

Signs and symptoms associated with diseases of the muscle, neuromuscular junction, or peripheral nerves. [from MeSH]

MedGen UID:
199852
Concept ID:
C0752252
Sign or Symptom
8.

Sarcopenia

Progressive decline in muscle mass due to aging which results in decreased functional capacity of muscles. [from MeSH]

MedGen UID:
163711
Concept ID:
C0872084
Disease or Syndrome
9.

Pathological Conditions, Anatomical

An abnormal structural condition of the human body, usually macroscopic, that is common to a variety of different diseases. [from MeSH]

MedGen UID:
155708
Concept ID:
C0752135
Pathologic Function
10.

Senility

MedGen UID:
115903
Concept ID:
C0231337
Finding
11.

Injectables

A drug or medicine that can be injected [from CHV]

MedGen UID:
88572
Concept ID:
C0086466
Pharmacologic Substance
12.

Atrophy

Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes. [from MeSH]

MedGen UID:
83084
Concept ID:
C0333641
Pathologic Function
13.

Clinical finding

clinical manifestations that can be either objective when observed by a physician, or subjective when perceived by the patient. [from CRISP]

MedGen UID:
19974
Concept ID:
C0037088
Sign or Symptom
14.

Neurologic Manifestations

Clinical signs and symptoms caused by nervous system injury or dysfunction. [from MeSH]

MedGen UID:
18017
Concept ID:
C0027854
Finding
15.

Disorder of nervous system

The brain, spinal cord, and nerves make up the nervous system. Together they control all the workings of the body. When something goes wrong with a part of your nervous system, you can have trouble moving, speaking, swallowing, breathing, or learning. You can also have problems with your memory, senses, or mood. There are more than 600 neurologic diseases. Major types include. - Diseases caused by faulty genes, such as Huntington's disease and muscular dystrophy. - Problems with the way the nervous system develops, such as spina bifida. - Degenerative diseases, where nerve cells are damaged or die, such as Parkinson's disease and Alzheimer's disease. - Diseases of the blood vessels that supply the brain, such as stroke. - Injuries to the spinal cord and brain. - Seizure disorders, such as epilepsy . - Cancer, such as brain tumors. - infections, such as meningitis.  [from MedlinePlus]

MedGen UID:
14336
Concept ID:
C0027765
Disease or Syndrome
16.

Muscle atrophy

A weakening, shrinking, and loss of muscle caused by disease or lack of use. Muscle wasting decreases strength and the ability to move. [from NCI_NCI-GLOSS]

MedGen UID:
7754
Concept ID:
C0026846
Pathologic Function
17.

Aging

Progressive damage to mitochondrial DNA (mtDNA) during life is thought to contribute to aging processes. This notion is supported by the observation of an aging-related accumulation in human mtDNA of oxidative and alkylation derivatives of nucleotides, of small deletions and insertions, and of large deletions, although their low frequency raises questions about their functional significance (Michikawa et al., 1999). [from OMIM]

MedGen UID:
1376
Concept ID:
C0001811
Organism Function
18.

New medication therapy needed for condition

MedGen UID:
782958
Concept ID:
C3661797
Finding
19.

Finding of size of kidney

MedGen UID:
660719
Concept ID:
C0577168
Finding
20.

Finding of size of skeletal muscle

MedGen UID:
658711
Concept ID:
C0575051
Finding
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