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Items: 1 to 20 of 23

1.

Tendinopathies

Clinical syndrome describing overuse tendon injuries characterized by a combination of PAIN, diffuse or localized swelling, and impaired performance. [from MeSH]

MedGen UID:
291538
Concept ID:
C1568272
Disease or Syndrome
2.

Oncostatin-M

Oncostatin-M (252 aa, ~28 kDa) is encoded by the human OSM gene. This protein plays a role in the regulation of cytokine production, the modulation of cell proliferation and the development and regeneration of the liver. [from NCI]

MedGen UID:
32815
Concept ID:
C0069535
Amino Acid, Peptide, or Protein; Pharmacologic Substance
3.

Collagen type I

A heterotrimeric fibrillar protein complex comprised of two collagen alpha-1(I) chains and one collagen alpha-2(I) chains. Type I collagen is the most abundant fibrillar collagen in humans and is present in scar tissue, tendons, ligaments, bone, dermis, dentin, and organ capsules. [from NCI]

MedGen UID:
21743
Concept ID:
C0041455
Amino Acid, Peptide, or Protein; Biologically Active Substance; Pharmacologic Substance
4.

Inflammation

A localized protective response resulting from injury or destruction of tissues. Inflammation serves to destroy, dilute, or wall off both the injurious agent and the injured tissue. In the acute phase, inflammation is characterized by the signs of pain, heat, redness, swelling, and loss of function. Histologically, inflammation involves a complex series of events, including dilatation of arterioles, capillaries, and venules, with increased permeability and blood flow; exudation of fluids, including plasma proteins; and leukocyte migration into the site of inflammation. [from NCI]

MedGen UID:
7072
Concept ID:
C0021368
Pathologic Function
5.

Tendon rupture

Breakage (tear) of a tendon. [from HPO]

MedGen UID:
508840
Concept ID:
C0151937
Injury or Poisoning
6.

Primary cortisol resistance

MedGen UID:
443921
Concept ID:
C2930863
Disease or Syndrome
7.

Chronic

Slow, creeping onset, slow progress and long continuance of disease manifestations. [from HPO]

MedGen UID:
104657
Concept ID:
C0205191
Temporal Concept
8.

Pain

An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS. [from MeSH]

MedGen UID:
45282
Concept ID:
C0030193
Sign or Symptom
9.

Infantile cortical hyperostosis

Caffey disease is characterized by massive subperiosteal new bone formation (usually involving the diaphyses of the long bones as well as the ribs, mandible, scapulae, and clavicles) typically associated with fever, joint swelling, and pain in children, with onset around age two months and spontaneous resolution by age two years. On rare occasion, the hyperostosis can be detected by ultrasound examination late in the third trimester of pregnancy. Limited follow-up information suggests that adults who had Caffey disease in childhood may manifest joint laxity, skin hyperextensibility, hernias, and an increased risk for bone fractures and/or deformities. [from GTR]

MedGen UID:
43781
Concept ID:
C0020497
Disease or Syndrome
10.

Tendinosis

A disorder of TENDONS characterized by COLLAGEN degeneration, other changes to tenocytes and the EXTRACELLULAR MATRIX, and a lack of inflammatory cells. It is caused by aging, MICROTRAUMA, or vascular compromise. Tendinosis is not a clinical diagnosis and can be confirmed only by histopathological findings. [from MeSH]

MedGen UID:
293673
Concept ID:
C1568363
Disease or Syndrome
11.

Dysfunction of posterior tibial tendon

A condition characterized by a broad range of progressive disorders ranging from TENOSYNOVITIS to tendon rupture with or without hindfoot collapse to a fixed, rigid, FLATFOOT deformity. Pathologic changes can involve associated tendons, ligaments, joint structures of the ANKLE, hindfoot, and midfoot. Posterior tibial tendon dysfunction is the most common cause of acquired flatfoot deformity in adults. [from MeSH]

MedGen UID:
209703
Concept ID:
C1136154
Disease or Syndrome
12.

Disease Attributes

Clinical characteristics of disease or illness. [from MeSH]

MedGen UID:
199876
Concept ID:
C0752357
Disease or Syndrome
13.

Avitene

MedGen UID:
149149
Concept ID:
C0733516
Amino Acid, Peptide, or Protein; Biomedical or Dental Material; Pharmacologic Substance
14.

Tendonitis

Inflammation of TENDONS. It is characterized by the degeneration of tendons accompanied by an inflammatory repair response, fibroblastic proliferation, and formation of granulation tissue. Tendinitis is not a clinical diagnosis and can be confirmed only by histopathological findings. [from MeSH]

MedGen UID:
21094
Concept ID:
C0039503
Disease or Syndrome
15.

Myopathy

A disorder of muscle unrelated to impairment of innervation or neuromuscular junction. [from HPO]

MedGen UID:
10135
Concept ID:
C0026848
Disease or Syndrome
16.

wounds

MedGen UID:
9475
Concept ID:
C0021501
Finding
17.

Disorder of foot

Anatomical and functional disorders affecting the foot. [from MeSH]

MedGen UID:
8889
Concept ID:
C0016510
Disease or Syndrome
18.

Disorder of musculoskeletal system

A category of diseases that involve muscles and bones. [from NCI]

MedGen UID:
6471
Concept ID:
C0026857
Disease or Syndrome
19.

Chronic disease

Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed) [from MeSH]

MedGen UID:
3453
Concept ID:
C0008679
Disease or Syndrome
20.

Disorder of Achilles tendon

MedGen UID:
825930
Concept ID:
C3840085
Disease or Syndrome
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