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Items: 1 to 20 of 28

1.

Corticosterone

An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437) [from MeSH]

MedGen UID:
41316
Concept ID:
C0010124
Hormone; Organic Chemical; Pharmacologic Substance
2.

Ethanol

If you are like many Americans, you drink alcohol at least occasionally. For many people, moderate drinking is probably safe. It may even have health benefits, including reducing your risk of certain heart problems. For most women and for most people over 65, moderate drinking is no more than three drinks a day or seven drinks per week. For men under 65, it is no more than four drinks a day or 14 drinks per week. Some people should not drink at all, including alcoholics, children, pregnant women, people taking certain medicines, and people with certain medical conditions. If you have questions about whether it is safe for you to drink, speak with your health care provider. Anything more than moderate drinking can be risky. Heavy drinking can lead to alcoholism and alcohol abuse, as well as injuries, liver disease, heart disease, cancer, and other health problems. It can also cause problems at home, at work, and with friends. NIH: National Institute on Alcohol Abuse and Alcoholism.  [from MedlinePlus]

MedGen UID:
186
Concept ID:
C0001962
Organic Chemical; Pharmacologic Substance
3.

corticotropin, human

A hormone made in the pituitary gland. ACTH acts on the outer part of the adrenal gland to control its release of corticosteroid hormones. More ACTH is made during times of stress. [from NCI_NCI-GLOSS]

MedGen UID:
896260
Concept ID:
C3818725
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
4.

Corticotropin-Releasing Hormone

A hormone synthesized in the hypothalamus and regulates the secretion of adrenocorticotropic hormone (ACTH). [from NCI]

MedGen UID:
3632
Concept ID:
C0010132
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
5.

Areflexia

Absence of neurologic reflexes such as the knee-jerk reaction. [from HPO]

MedGen UID:
115943
Concept ID:
C0234146
Finding
6.

Metyrapone

An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME. [from MeSH]

MedGen UID:
10013
Concept ID:
C0025876
Hormone; Organic Chemical; Pharmacologic Substance
7.

Dependence

The psychological or physiological need to take a substance in oder to experience its effects or to avoid the effects of its absence. [from NCI]

MedGen UID:
141006
Concept ID:
C0439857
Mental or Behavioral Dysfunction
8.

Addictive behavior

A recurrent pattern of behavior that is characeterized by the failure to resist an impulse, drive, or temptation to perform an act that is harmful to the person or to others. The repetitive engagement in these behaviors ultimately interferes with functioning in other domains. [from HPO]

MedGen UID:
88373
Concept ID:
C0085281
Mental or Behavioral Dysfunction
9.

Metopirone

MedGen UID:
147082
Concept ID:
C0700006
Indicator, Reagent, or Diagnostic Aid; Organic Chemical; Pharmacologic Substance
10.

Obsessive-compulsive behavior

Recurrent obsessions or compulsions that are severe enough to be time consuming (i.e., they take more than 1 hour a day) or cause marked distress or significant impairment (DSM-IV). [from HPO]

MedGen UID:
109373
Concept ID:
C0600104
Mental or Behavioral Dysfunction
11.

Neurobehavioral Manifestations

Signs and symptoms of higher cortical dysfunction caused by organic conditions. These include certain behavioral alterations and impairments of skills involved in the acquisition, processing, and utilization of knowledge or information. [from MeSH]

MedGen UID:
105653
Concept ID:
C0525041
Sign or Symptom
12.

Impulsivity

An act performed without delay, reflection, voluntary direction or obvious control in response to a stimulus. [from MeSH]

MedGen UID:
43850
Concept ID:
C0021125
Individual Behavior
13.

Clinical finding

clinical manifestations that can be either objective when observed by a physician, or subjective when perceived by the patient. [from CRISP]

MedGen UID:
19974
Concept ID:
C0037088
Sign or Symptom
14.

Neurologic Manifestations

Clinical signs and symptoms caused by nervous system injury or dysfunction. [from MeSH]

MedGen UID:
18017
Concept ID:
C0027854
Finding
15.

Disorder of nervous system

The brain, spinal cord, and nerves make up the nervous system. Together they control all the workings of the body. When something goes wrong with a part of your nervous system, you can have trouble moving, speaking, swallowing, breathing, or learning. You can also have problems with your memory, senses, or mood. There are more than 600 neurologic diseases. Major types include. - Diseases caused by faulty genes, such as Huntington's disease and muscular dystrophy. - Problems with the way the nervous system develops, such as spina bifida. - Degenerative diseases, where nerve cells are damaged or die, such as Parkinson's disease and Alzheimer's disease. - Diseases of the blood vessels that supply the brain, such as stroke. - Injuries to the spinal cord and brain. - Seizure disorders, such as epilepsy . - Cancer, such as brain tumors. - infections, such as meningitis.  [from MedlinePlus]

MedGen UID:
14336
Concept ID:
C0027765
Disease or Syndrome
16.

Psychomotor Disorders

abnormalities of motor function that are associated with organic and nonorganic cognitive disorders. [from CRISP]

MedGen UID:
11008
Concept ID:
C0033922
Mental or Behavioral Dysfunction
17.

Hormones, Hormone Substitutes, and Hormone Antagonists

A collective grouping for both naturally occurring and synthetic hormones, substitutes, and antagonists. [from MeSH]

MedGen UID:
6887
Concept ID:
C0019934
Pharmacologic Substance
18.

Adrenal Cortex Hormones

Any steroid hormone made in the adrenal cortex (the outer part of the adrenal gland). They are also made in the laboratory. Corticosteroids have many different effects in the body, and are used to treat many different conditions. They may be used as hormone replacement, to suppress the immune system, and to treat some side effects of cancer and its treatment. Corticosteroids are also used to treat certain lymphomas and lymphoid leukemias. [from NCI_NCI-GLOSS]

MedGen UID:
1767
Concept ID:
C0001617
Hormone; Organic Chemical; Pharmacologic Substance
19.

Alcohol

A class of compounds where a hydroxyl (OH) group is attached to single bonded hydrocarbons. Alcohols are classified according to the position of the carbon atom with the attached hydroxyl group (i.e. primary alcohols are alcohols with the OH group attached to the primary carbon atom, C1). Uses include solvents, astringents, and anti-infective activity. [from NCI]

MedGen UID:
1400
Concept ID:
C0001975
Organic Chemical; Pharmacologic Substance
20.

Clinical finding absent

MedGen UID:
699920
Concept ID:
C1276745
Finding
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