Format
Items per page

Send to:

Choose Destination

Links from PubMed

Items: 1 to 20 of 41

1.

ribavirin

A synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses. Ribavirin is incorporated into viral RNA, thereby inhibiting viral RNA synthesis, inducing viral genome mutations, and inhibiting normal viral replication. [from NCI]

MedGen UID:
48459
Concept ID:
C0035525
Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
2.

Hepatitis C

Hepatitis C is one type of hepatitis - a liver disease - caused by the hepatitis C virus (HCV). It usually spreads through contact with infected blood. It can also spread through sex with an infected person and from mother to baby during childbirth. Most people who are infected with hepatitis C don't have any symptoms for years. A blood test can tell if you have it. Usually, hepatitis C does not get better by itself. The infection can last a lifetime and may lead to scarring of the liver or liver cancer. Medicines sometimes help, but side effects can be a problem. Serious cases may need a liver transplant. There is no vaccine for HCV. NIH: National Institute of Diabetes and Digestive and Kidney Diseases.  [from MedlinePlus]

MedGen UID:
42425
Concept ID:
C0019196
Disease or Syndrome
3.

Interferon Alfa-2a

A non-glycosylated recombinant human alpha interferon, subtype 2a, produced in the bacterium E. coli. Interferon alpha-2a binds to its specific cell-surface receptor, resulting in the transcription and translation of genes whose protein products have antiviral, antiproliferative, anticancer, and immune modulating effects. (NCI04) [from NCI]

MedGen UID:
5845
Concept ID:
C0021734
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
4.

Hepatitis

Your liver is the largest organ inside your body. It helps your body digest food, store energy, and remove poisons. Hepatitis is an inflammation of the liver. . Viruses cause most cases of hepatitis. The type of hepatitis is named for the virus that causes it; for example, hepatitis A, hepatitis B or hepatitis C. Drug or alcohol use can also cause hepatitis. In other cases, your body mistakenly attacks healthy cells in the liver. Some people who have hepatitis have no symptoms. Others may have. -Loss of appetite. -Nausea and vomiting. -Diarrhea. -Dark-colored urine and pale bowel movements. -Stomach pain. -Jaundice, yellowing of skin and eyes. Some forms of hepatitis are mild, and others can be serious. Some can lead to scarring, called cirrhosis, or to liver cancer. Sometimes hepatitis goes away by itself. If it does not, it can be treated with drugs. Sometimes hepatitis lasts a lifetime. Vaccines can help prevent some viral forms.  [from MedlinePlus]

MedGen UID:
5515
Concept ID:
C0019158
Disease or Syndrome
5.

human leukocyte interferon

A biological response modifier (a substance that can improve the body's natural response to infection and disease). Interferons interfere with the division of cancer cells and can slow tumor growth. There are several types of interferons, including interferon-alpha, -beta, and -gamma. These substances are normally produced by the body. They are also made in the laboratory for use in treating cancer and other diseases. [from NCI]

MedGen UID:
196514
Concept ID:
C0733470
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
6.

pegylated interferon alfa

A covalent conjugate of recombinant interferon alpha and polyethylene glycol (PEG), used as an antiviral and antineoplastic agent. The biological activity of this agent is derived from its interferon alpha protein moiety. Interferons alfa bind to specific cell-surface receptors, leading to the transcription and translation of genes whose protein products mediate antiviral, antiproliferative, anticancer, and immune-modulating effects. The PEG moiety lowers the clearance of interferon alpha, thereby extending the duration of its therapeutic effects, but may also reduce interferon-mediated stimulation of an immune response. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=43151&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=43151&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2491" NCI Thesaurus) [from PDQ]

MedGen UID:
173304
Concept ID:
C0907160
Immunologic Factor; Organic Chemical; Pharmacologic Substance
7.

Chronic hepatitis

INFLAMMATION of the LIVER with ongoing hepatocellular injury for 6 months or more, characterized by NECROSIS of HEPATOCYTES and inflammatory cell (LEUKOCYTES) infiltration. Chronic hepatitis can be caused by viruses, medications, autoimmune diseases, and other unknown factors. [from MeSH]

MedGen UID:
9223
Concept ID:
C0019189
Disease or Syndrome
8.

Interferon-alpha

a protein produced by the body in response to an infection [from CHV]

MedGen UID:
7985
Concept ID:
C0002199
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
9.

Interferon

Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions. [from MeSH]

MedGen UID:
5847
Concept ID:
C0021747
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
10.

Pseudohyperkalemia Cardiff

Cryohydrocytosis is an exceedingly rare condition characterized by a mild stomatocytic hemolytic state with hyperbilirubinemia. A hallmark of this condition is that red blood cells (RBCs) lyse on storage at 4 degrees centigrade. RBC cation permeability is increased at 37 degrees centigrade, and the cells also accumulate sodium in the cold (summary by Coles et al., 1999). Patients present with fatigue, mild anemia, and pseudohyperkalemia due to a potassium leak from the RBCs (summary by Bogdanova et al., 2010). For a discussion of clinical and genetic heterogeneity of the hereditary stomatocytoses, see 194380. [from OMIM]

MedGen UID:
396137
Concept ID:
C1861453
Disease or Syndrome
11.

Resistance to hepatitis C virus

MedGen UID:
332112
Concept ID:
C1836031
Finding
12.

Disease Response

The pathologic and/or clinical changes that result from treatment. The changes may include eradication of detectable disease, stabilization of disease, or disease progression. [from NCI]

MedGen UID:
309976
Concept ID:
C1704632
Finding
13.

Well Differentiated Liposarcoma

An intermediate malignant mesenchymal neoplasm composed entirely or in part of mature adipocytes that vary in cell size and show at least focal nuclear atypia in adipocytes and stromal cells. Recurrent cytogenetic aberrations are specifically associated with this entity: supernumerary ring and giant marker chromosomes with amplification of MDM2 and, often, CDK4. [from NCI]

MedGen UID:
237164
Concept ID:
C1370889
Neoplastic Process
14.

Hepatitis C, Chronic

INFLAMMATION of the LIVER in humans that is caused by HEPATITIS C VIRUS lasting six months or more. Chronic hepatitis C can lead to LIVER CIRRHOSIS. [from MeSH]

MedGen UID:
105623
Concept ID:
C0524910
Disease or Syndrome
15.

Virazole

MedGen UID:
301227
Concept ID:
C1622085
Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
16.

Ribasphere

MedGen UID:
296034
Concept ID:
C1564336
Biologically Active Substance; Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
17.

Virazide

MedGen UID:
289722
Concept ID:
C1564036
Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
18.

Rebetol

MedGen UID:
223940
Concept ID:
C1170576
Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
19.

Antimicrobial substance

Any substance or process that kills germs (bacteria, viruses, and other microorganisms that can cause infection and disease). [from NCI]

MedGen UID:
209727
Concept ID:
C1136254
Pharmacologic Substance
20.

Ribamide

MedGen UID:
152359
Concept ID:
C0702024
Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
Format
Items per page

Send to:

Choose Destination

Supplemental Content

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center