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Items: 5

1.

Calcium oxalate urolithiasis

Kleta (2006) reviewed aspects of renal stone disease. Nephrolithiasis and urolithiasis remain major public health problems of largely unknown cause. While disorders such as cystinuria (220100) and primary hyperoxaluria (see 259900) that have nephrolithiasis as a major feature have advanced understanding of the metabolic and physiologic processes of stone formation in general, they have not addressed the etiology of calcium oxalate stone formation, responsible for approximately 75% of urolithiasis cases in humans. Men are affected twice as often as women, but children show no such gender bias. The recurrence rate is also high. In populations of European ancestry, 5 to 10% of adults experience the painful precipitation of calcium oxalate in their urinary tracts. Thorleifsson et al. (2009) noted that between 35 and 65% of hypercalciuric stone formers and up to 70% of subjects with hypercalciuria have relatives with nephrolithiasis, and twin studies have estimated the heritability of kidney stones to be 56%. [from GTR]

MedGen UID:
318935
Concept ID:
C1833683
Disease or Syndrome
2.

Nephrolithiasis

Formation of stones in the KIDNEY. [from MeSH]

MedGen UID:
98227
Concept ID:
C0392525
Disease or Syndrome
3.

Calculus = phosphate

MedGen UID:
508042
Concept ID:
C0031600
Finding
4.

Uric acid nephrolithiasis

Nephrolithiasis in which the composition of the stone(s) is predominantly uric acid.(NICHD) [from NCI]

MedGen UID:
140791
Concept ID:
C0403719
Disease or Syndrome
5.

Ammonium phosphate

MedGen UID:
13839
Concept ID:
C0051724
Inorganic Chemical; Pharmacologic Substance
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