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Items: 1 to 20 of 22

1.

TNF receptor-associated periodic fever syndrome (TRAPS)

Tumor necrosis factor receptor-associated periodic syndrome (commonly known as TRAPS) is a condition characterized by recurrent episodes of fever. These fevers typically last about 3 weeks but can last from a few days to a few months. The frequency of the episodes varies greatly among affected individuals; fevers can occur anywhere between every 6 weeks to every few years. Some individuals can go many years without having a fever episode. Fever episodes usually occur spontaneously, but sometimes they can be brought on by a variety of triggers, such as minor injury, infection, stress, exercise, or hormonal changes.During episodes of fever, people with TRAPS can have additional signs and symptoms. These include abdominal and muscle pain and a spreading skin rash, typically found on the limbs. Affected individuals may also experience puffiness or swelling in the skin around the eyes (periorbital edema); joint pain; and inflammation in various areas of the body including the eyes, heart muscle, certain joints, throat, or mucous membranes such as the moist lining of the mouth and digestive tract. Occasionally, people with TRAPS develop amyloidosis, an abnormal buildup of a protein called amyloid in the kidneys that can lead to kidney failure. It is estimated that 15 to 20 percent of people with TRAPS develop amyloidosis, typically in mid-adulthood.The fever episodes characteristic of TRAPS can begin at any age, from infancy to late adulthood, but most people have their first episode in childhood.
[from GHR]

MedGen UID:
226899
Concept ID:
C1275126
Congenital Abnormality
2.

Infection

Invasion of the host organism by microorganisms that can cause pathological conditions or diseases. [from MeSH]

MedGen UID:
811352
Concept ID:
C3714514
Pathologic Function
3.

Autoimmune state

Process whereby the immune system reacts against the body's own tissues. Autoimmunity may produce or be caused by AUTOIMMUNE DISEASES. [from MeSH]

MedGen UID:
2136
Concept ID:
C0004368
Pathologic Function
4.

Much

A subjective response indicating that something is or was a large amount. [from NCI]

MedGen UID:
923949
Concept ID:
C4281574
Finding
5.

Employed

MedGen UID:
642401
Concept ID:
C0557351
Finding
6.

Autoimmunity

The occurrence of an immune reaction against the organism's own cells or tissues. [from HPO]

MedGen UID:
505423
Concept ID:
CN002679
Finding
7.

Recruitment

MedGen UID:
78772
Concept ID:
C0271510
Disease or Syndrome
8.

Protozoan infection

Infections with unicellular organisms formerly members of the subkingdom Protozoa. [from MeSH]

MedGen UID:
19532
Concept ID:
C0033740
Disease or Syndrome
9.

Inhibition

MedGen UID:
5809
Concept ID:
C0021469
Molecular Function
10.

Autoimmune disease

Your body's immune system protects you from disease and infection. But if you have an autoimmune disease, your immune system attacks healthy cells in your body by mistake. Autoimmune diseases can affect many parts of the body. No one is sure what causes autoimmune diseases. They do tend to run in families. Women - particularly African-American, Hispanic-American, and Native-American women - have a higher risk for some autoimmune diseases. There are more than 80 types of autoimmune diseases, and some have similar symptoms. This makes it hard for your health care provider to know if you really have one of these diseases, and if so, which one. Getting a diagnosis can be frustrating and stressful. Often, the first symptoms are fatigue, muscle aches and a low fever. The classic sign of an autoimmune disease is inflammation, which can cause redness, heat, pain and swelling. The diseases may also have flare-ups, when they get worse, and remissions, when symptoms get better or disappear. Treatment depends on the disease, but in most cases one important goal is to reduce inflammation. Sometimes doctors prescribe corticosteroids or other drugs that reduce your immune response.  [from MedlinePlus]

MedGen UID:
2135
Concept ID:
C0004364
Disease or Syndrome
11.

Protozoan Infections, Animal

Infections with unicellular organisms formerly members of the subkingdom Protozoa. The infections may be experimental or veterinary. [from MeSH]

MedGen UID:
46170
Concept ID:
C0033741
Disease or Syndrome
12.

Disease caused by parasite

Parasites are living things that use other living things - like your body - for food and a place to live. You can get them from contaminated food or water, a bug bite, or sexual contact. Some parasitic diseases are easily treated and some are not. Parasites range in size from tiny, one-celled organisms called protozoa to worms that can be seen with the naked eye. Some parasitic diseases occur in the United States. Contaminated water supplies can lead to Giardia infections. Cats can transmit toxoplasmosis, which is dangerous for pregnant women. Others, like malaria, are common in other parts of the world. . If you are traveling, it's important to drink only water you know is safe. Prevention is especially important. There are no vaccines for parasitic diseases. Some medicines are available to treat parasitic infections.  [from MedlinePlus]

MedGen UID:
45325
Concept ID:
C0030499
Disease or Syndrome
13.

Toxoplasmosis, Animal

Acquired infection of non-human animals by organisms of the genus TOXOPLASMA. [from MeSH]

MedGen UID:
21598
Concept ID:
C0040559
Disease or Syndrome
14.

Toxoplasmosis

Toxoplasmosis is a disease caused by the parasite Toxoplasma gondii. More than 60 million people in the U.S. have the parasite. Most of them don't get sick. But the parasite causes serious problems for some people. These include people with weak immune systems and babies whose mothers become infected for the first time during pregnancy. Problems can include damage to the brain, eyes, and other organs. You can get toxoplasmosis from . - Waste from an infected cat. - Eating contaminated meat that is raw or not well cooked . - Using utensils or cutting boards after they've had contact with contaminated raw meat . - Drinking infected water . - Receiving an infected organ transplant or blood transfusion. Most people with toxoplasmosis don't need treatment. There are drugs to treat it for pregnant women and people with weak immune systems. . Centers for Disease Control and Prevention.  [from MedlinePlus]

MedGen UID:
21597
Concept ID:
C0040558
Disease or Syndrome
15.

Parasitic Diseases, Animal

Animal diseases caused by PARASITES. [from MeSH]

MedGen UID:
18300
Concept ID:
C0030500
Disease or Syndrome
16.

Infection by Besnoitia

MedGen UID:
14080
Concept ID:
C0005146
Disease or Syndrome
17.

Animal Diseases

Diseases that occur in VERTEBRATE animals. [from MeSH]

MedGen UID:
8091
Concept ID:
C0003047
Disease or Syndrome
18.

Infection by Histomonas

MedGen UID:
5574
Concept ID:
C0019640
Disease or Syndrome
19.

Coccidiosis

Protozoan infection found in animals and man. It is caused by several different genera of COCCIDIA. [from MeSH]

MedGen UID:
3138
Concept ID:
C0009187
Disease or Syndrome
20.

Found entrapped

MedGen UID:
744724
Concept ID:
C1997680
Finding
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