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Items: 5

1.

Risperidone

A benzisoxazole derivative with antipsychotic property. Risperidone selectively antagonizes serotonin (5-HT) effects via cortical 5-HT2 receptor, and, to a lesser extent, competes with dopamine at the limbic dopamine D2 receptor. The antagonism leads to decreased psychotic effects, such as hallucinations and delusions. In addition, risperidone has low to moderate affinity for histamine H1, 5-HT1A, 5-HT1C, and 5-HT1D receptors, while it has weak affinity for dopamine D1 and haloperidol-sensitive sigma site receptors. [from NCI]

MedGen UID:
34414
Concept ID:
C0073393
Organic Chemical; Pharmacologic Substance
2.

Chronic

Slow, creeping onset, slow progress and long continuance of disease manifestations. [from HPO]

MedGen UID:
104657
Concept ID:
C0205191
Temporal Concept
3.

Lyogen

MedGen UID:
148755
Concept ID:
C0701358
Organic Chemical; Pharmacologic Substance
4.

Prolixin

MedGen UID:
18671
Concept ID:
C0033390
Organic Chemical; Pharmacologic Substance
5.

Fluphenazine

A phenothiazine used in the treatment of PSYCHOSES. Its properties and uses are generally similar to those of CHLORPROMAZINE. [from MeSH]

MedGen UID:
8870
Concept ID:
C0016368
Organic Chemical; Pharmacologic Substance
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