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Items: 1 to 20 of 39

1.

BI 207127

MedGen UID:
844252
Concept ID:
C3886693
Organic Chemical; Pharmacologic Substance
2.

Infection

The invasion of an organism's body tissues by disease-causing agents and their multiplication, as well as the reaction by the host to these organisms and/or toxins that the organisms produce. [from NCI]

MedGen UID:
811352
Concept ID:
C3714514
Pathologic Function
3.

ribavirin

A nucleoside antimetabolite antiviral agent that blocks nucleic acid synthesis and is used against both RNA and DNA viruses. [from MeSH]

MedGen UID:
48459
Concept ID:
C0035525
Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
4.

Resistance to hepatitis C virus

MedGen UID:
332112
Concept ID:
C1836031
Finding
5.

Chronic

Slow, creeping onset, slow progress and long continuance of disease manifestations. [from HPO]

MedGen UID:
104657
Concept ID:
C0205191
Temporal Concept
6.

Peptide hydrolase inhibitor

Any substance that inhibits a protease, an enzyme that breaks peptide bonds. Proteases are required for many cell processes and inhibition of proteases can inhibit viral replication, inflammatory responses, proliferation, and tumor growth. [from NCI]

MedGen UID:
18701
Concept ID:
C0033607
Pharmacologic Substance
7.

Hepatitis C

A viral infection caused by the hepatitis C virus. [from NCI]

MedGen UID:
42425
Concept ID:
C0019196
Disease or Syndrome
8.

Hepatitis

INFLAMMATION of the LIVER. [from MeSH]

MedGen UID:
5515
Concept ID:
C0019158
Disease or Syndrome
9.

Virologic Response

A description of the change in viral disease status in response to treatment. [from NCI]

MedGen UID:
883196
Concept ID:
C4053862
Finding
10.

Infections

MedGen UID:
678472
Concept ID:
C0851162
Disease or Syndrome
11.

Noonan syndrome 3

Noonan syndrome (NS) is characterized by characteristic facies, short stature, congenital heart defect, and developmental delay of variable degree. Other findings can include broad or webbed neck, unusual chest shape with superior pectus carinatum and inferior pectus excavatum, cryptorchidism, varied coagulation defects, lymphatic dysplasias, and ocular abnormalities. Although birth length is usually normal, final adult height approaches the lower limit of normal. Congenital heart disease occurs in 50%-80% of individuals. Pulmonary valve stenosis, often with dysplasia, is the most common heart defect and is found in 20%-50% of individuals. Hypertrophic cardiomyopathy, found in 20%-30% of individuals, may be present at birth or develop in infancy or childhood. Other structural defects include atrial and ventricular septal defects, branch pulmonary artery stenosis, and tetralogy of Fallot. Up to one fourth of affected individuals have mild intellectual disability, and language impairments in general are more common in NS than in the general population. [from GTR]

MedGen UID:
349931
Concept ID:
C1860991
Disease or Syndrome
12.

Discontinued

To stop or end, permanently or temporarily. [from NCI]

MedGen UID:
303183
Concept ID:
C1444662
Finding
13.

Mild

Having a relatively minor degree of severity. For quantitative traits, a deviation of between two and three standard deviations from the appropriate population mean. [from HPO]

MedGen UID:
268697
Concept ID:
C1513302
Finding
14.

Severe

Having a high degree of severity. For quantitative traits, a deviation of between four and five standard deviations from the appropriate population mean. [from HPO]

MedGen UID:
104640
Concept ID:
C0205082
Qualitative Concept
15.

Cutaneous photosensitivity

An increased sensitivity of the skin to light. Photosensitivity may result in a rash upon exposure to the sun (which is known as photodermatosis). Photosensitivity can be diagnosed by phototests in which light is shone on small areas of skin. [from HPO]

MedGen UID:
87601
Concept ID:
C0349506
Finding; Pathologic Function
16.

Skin rash

A red eruption of the skin. [from HPO]

MedGen UID:
8732
Concept ID:
C0015230
Finding; Sign or Symptom
17.

Virazole

MedGen UID:
301227
Concept ID:
C1622085
Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
18.

Ribasphere

MedGen UID:
296034
Concept ID:
C1564336
Biologically Active Substance; Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
19.

Virazide

MedGen UID:
289722
Concept ID:
C1564036
Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
20.

Molecular Mechanisms of Pharmacological Action

Pharmacological activities at the molecular level of DRUGS and other exogenous compounds that are used to treat DISEASES and affect normal BIOCHEMISTRY. [from MeSH]

MedGen UID:
226255
Concept ID:
C1258062
Molecular Function
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