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Items: 1 to 20 of 63

1.

Anemia

A reduction in erythrocytes volume or hemoglobin concentration. [from HPO]

MedGen UID:
1526
Concept ID:
C0002871
Disease or Syndrome
2.

Left ventricular diastolic dysfunction

MedGen UID:
696562
Concept ID:
C1273070
Disease or Syndrome
3.

Pressure

MedGen UID:
632176
Concept ID:
C0460139
Finding
4.

Left

Being located on the left side of the body. [from HPO]

MedGen UID:
618170
Concept ID:
C0443246
Spatial Concept
5.

Exercise intolerance

A reduction in the ability to perform or withstand activities that induce physical or mental exertion. [from NCI]

MedGen UID:
603270
Concept ID:
C0424551
Finding; Finding
6.

Diastolic dysfunction

Impairment in the filling of the ventricles during diastole. Causes include hypertrophic and restrictive cardiomyopathies, coronary artery disease, chronic high blood pressure, aortic stenosis, and aging. [from NCI]

MedGen UID:
105464
Concept ID:
C0520863
Pathologic Function
7.

Exercise intolerance

MedGen UID:
66841
Concept ID:
C0241885
8.

Anemia

A laboratory test result demonstrating decreased levels of hemoglobin in a biological specimen. [from NCI]

MedGen UID:
56401
Concept ID:
C0162119
Finding
9.

Hb SS disease

Sickle cell disease (SCD) is characterized by intermittent vaso-occlusive events and chronic hemolytic anemia. Vaso-occlusive events result in tissue ischemia leading to acute and chronic pain as well as organ damage that can affect any organ system, including the bones, spleen, liver, brain, lungs, kidneys, and joints. Dactylitis (pain and/or swelling of the hands or feet) is often the earliest manifestation of SCD. In children, the spleen can become engorged with blood cells in a “splenic sequestration.” The spleen is particularly vulnerable to infarction and the majority of individuals with SCD who are not on hydroxyurea or transfusion therapy become functionally asplenic in early childhood, increasing their risk for certain types of bacterial infections. Acute chest syndrome is a major cause of mortality in SCD. Chronic hemolysis can result in varying degrees of anemia, jaundice, cholelithiasis, and delayed growth and sexual maturation. Individuals with the highest rates of hemolysis are predisposed to pulmonary artery hypertension, priapism, and leg ulcers but may be relatively protected from vaso-occlusive pain. [from GTR]

MedGen UID:
287
Concept ID:
C0002895
Disease or Syndrome
10.

Sildenafil

A drug used to treat erectile dysfunction. Sildenafil relaxes the smooth muscle of the penis to allow increased blood flow and erection. It is a type of phosphodiesterase inhibitor. [from NCI_NCI-GLOSS]

MedGen UID:
102095
Concept ID:
C0529793
Organic Chemical; Pharmacologic Substance
11.

Hemolysis

The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity. [from MeSH]

MedGen UID:
42402
Concept ID:
C0019054
Pathologic Function
12.

HEMOGLOBIN S

An abnormal hemoglobin resulting from the substitution of valine for glutamic acid at position 6 of the beta chain of the globin moiety. The heterozygous state results in sickle cell trait, the homozygous in sickle cell anemia. [from MeSH]

MedGen UID:
42399
Concept ID:
C0019043
Amino Acid, Peptide, or Protein; Biologically Active Substance
13.

Erythropoietin

Glycoprotein hormone, secreted chiefly by the KIDNEY in the adult and the LIVER in the FETUS, that acts on erythroid stem cells of the BONE MARROW to stimulate proliferation and differentiation. [from MeSH]

MedGen UID:
41863
Concept ID:
C0014822
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
14.

Urea

A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids. [from MeSH]

MedGen UID:
21773
Concept ID:
C0041942
Biologically Active Substance; Organic Chemical; Pharmacologic Substance
15.

Hypertension

Blood pressure that is abnormally high. [from NCI]

MedGen UID:
6969
Concept ID:
C0020538
Disease or Syndrome
16.

Delay

MedGen UID:
879911
Concept ID:
CN235300
Finding
17.

Independent

MedGen UID:
721426
Concept ID:
C1299583
Finding
18.

Hypertension

A finding of increased blood pressure; not necessarily hypertensive disorder [from SNOMEDCT_US]

MedGen UID:
635666
Concept ID:
C0497247
Finding
19.

Pulmonary artery systolic pressure

The blood pressure in the pulmonary artery during the contraction of the left ventricle of the heart. [from NCI]

MedGen UID:
606581
Concept ID:
C0428643
Finding
20.

Hemolytic anemia

A type of anemia caused by premature destruction of red blood cells (hemolysis). [from HPO]

MedGen UID:
504983
Concept ID:
CN001698
Finding
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