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Items: 1 to 20 of 34

1.

Insulin resistance

Increased resistance towards insulin, that is, diminished effectiveness of insulin in reducing blood glucose levels. [from HPO]

MedGen UID:
43904
Concept ID:
C0021655
Pathologic Function
2.

Hepatitis C

A viral infection caused by the hepatitis C virus. [from NCI]

MedGen UID:
42425
Concept ID:
C0019196
Disease or Syndrome
3.

Insulin

Insulin (51 aa, ~6 kDa) is encoded by the human INS gene. This protein is involved in the direct regulation of glucose metabolism. [from NCI]

MedGen UID:
5827
Concept ID:
C0021641
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
4.

Hepatitis

Your liver is the largest organ inside your body. It helps your body digest food, store energy, and remove poisons. Hepatitis is an inflammation of the liver. . Viruses cause most cases of hepatitis. The type of hepatitis is named for the virus that causes it; for example, hepatitis A, hepatitis B or hepatitis C. Drug or alcohol use can also cause hepatitis. In other cases, your body mistakenly attacks healthy cells in the liver. Some people who have hepatitis have no symptoms. Others may have. -Loss of appetite. -Nausea and vomiting. -Diarrhea. -Dark-colored urine and pale bowel movements. -Stomach pain. -Jaundice, yellowing of skin and eyes. Some forms of hepatitis are mild, and others can be serious. Some can lead to scarring, called cirrhosis, or to liver cancer. Sometimes hepatitis goes away by itself. If it does not, it can be treated with drugs. Sometimes hepatitis lasts a lifetime. Vaccines can help prevent some viral forms.  [from MedlinePlus]

MedGen UID:
5515
Concept ID:
C0019158
Disease or Syndrome
5.

Improved

Condition changed and/or recovered [from CCC]

MedGen UID:
512204
Concept ID:
C0184511
Finding
6.

Insulin resistance

Increased resistance towards insulin, that is, diminished effectiveness of insulin in reducing blood glucose levels. [from HPO]

MedGen UID:
504630
Concept ID:
CN000801
Finding
7.

Hepatitis C, Chronic

INFLAMMATION of the LIVER in humans that is caused by HEPATITIS C VIRUS lasting six months or more. Chronic hepatitis C can lead to LIVER CIRRHOSIS. [from MeSH]

MedGen UID:
105623
Concept ID:
C0524910
Disease or Syndrome
8.

Chronic

Slow, creeping onset, slow progress and long continuance of disease manifestations. [from HPO]

MedGen UID:
104657
Concept ID:
C0205191
Temporal Concept
9.

Chronic hepatitis

INFLAMMATION of the LIVER with ongoing hepatocellular injury for 6 months or more, characterized by NECROSIS of HEPATOCYTES and inflammatory cell (LEUKOCYTES) infiltration. Chronic hepatitis can be caused by viruses, medications, autoimmune diseases, and other unknown factors. [from MeSH]

MedGen UID:
9223
Concept ID:
C0019189
Disease or Syndrome
10.

Interferon-alpha

a protein produced by the body in response to an infection [from CHV]

MedGen UID:
7985
Concept ID:
C0002199
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
11.

Indicated

MedGen UID:
731837
Concept ID:
C1444656
Finding
12.

Independent

MedGen UID:
721426
Concept ID:
C1299583
Finding
13.

Resistance to hepatitis C virus

MedGen UID:
332112
Concept ID:
C1836031
Finding
14.

human leukocyte interferon

Human interferons have been classified into 3 groups: alpha, beta, and gamma. Both alpha- and beta-IFNs, previously designated type I, are acid-stable, but they differ immunologically and in regard to some biologic and physiochemical properties. The IFNs produced by virus-stimulated leukocytes (leukocyte IFNs) are predominantly of the alpha type. Those produced by lymphoblastoid cells are about 90% alpha and 10% beta. Induced fibroblasts produce mainly or exclusively the beta type. The alpha- and beta-IFNs differ widely in amino acid sequence. The gamma or immune IFNs, which are produced by T lymphocytes in response to mitogens or to antigens to which they are sensitized, are acid-labile and serologically distinct from alpha- and beta-IFNs. (from OMIM 147570) [from NCI]

MedGen UID:
196514
Concept ID:
C0733470
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
15.

Mass of body structure

A benign or malignant pathologic structure in any part of the body, resulting from a neoplastic accumulation of cells, inflammatory cells, or cystic changes. [from NCI]

MedGen UID:
108287
Concept ID:
C0577559
Finding
16.

Interferon

Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions. [from MeSH]

MedGen UID:
5847
Concept ID:
C0021747
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
17.

Interferon Alfa-2a

A non-glycosylated recombinant human alpha interferon, subtype 2a, produced in the bacterium E. coli. Interferon alpha-2a binds to its specific cell-surface receptor, resulting in the transcription and translation of genes whose protein products have antiviral, antiproliferative, anticancer, and immune modulating effects. (NCI04) Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=467189&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=467189&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1952" NCI Thesaurus) [from PDQ]

MedGen UID:
5845
Concept ID:
C0021734
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
18.

Disorder of glucose metabolism

Pathological conditions in which the BLOOD GLUCOSE cannot be maintained within the normal range, such as in HYPOGLYCEMIA and HYPERGLYCEMIA. Etiology of these disorders varies. Plasma glucose concentration is critical to survival for it is the predominant fuel for the CENTRAL NERVOUS SYSTEM. [from MeSH]

MedGen UID:
226229
Concept ID:
C1257958
Disease or Syndrome
19.

Antimicrobial substance

Any substance or process that kills germs (bacteria, viruses, and other microorganisms that can cause infection and disease). [from NCI_NCI-GLOSS]

MedGen UID:
209727
Concept ID:
C1136254
Pharmacologic Substance
20.

Disease due to Flaviviridae

Infections with viruses of the family FLAVIVIRIDAE. [from MeSH]

MedGen UID:
104898
Concept ID:
C0206609
Disease or Syndrome
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