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Items: 8

1.

Methotrexate

An antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities. Methotrexate binds to and inhibits the enzyme dihydrofolate reductase, resulting in inhibition of purine nucleotide and thymidylate synthesis and, subsequently, inhibition of DNA and RNA syntheses. Methotrexate also exhibits potent immunosuppressant activity although the mechanism(s) of actions is unclear. [from NCI]

MedGen UID:
9996
Concept ID:
C0025677
Organic Chemical; Pharmacologic Substance
2.

7-hydroxymethotrexate

MedGen UID:
13456
Concept ID:
C0049910
Organic Chemical; Pharmacologic Substance
3.

Absence

MedGen UID:
739164
Concept ID:
C1689985
Anatomical Abnormality
4.

Glycoprotein, renal

MedGen UID:
330713
Concept ID:
C1841864
Finding
5.

Examined for

Having been subjected to inspection or evaluation. [from NCI]

MedGen UID:
83047
Concept ID:
C0332128
Finding
6.

Mexate

MedGen UID:
61461
Concept ID:
C0205839
Organic Chemical; Pharmacologic Substance
7.

Feces in urine

MedGen UID:
660746
Concept ID:
C0577200
Finding
8.

Urine not examined

MedGen UID:
600496
Concept ID:
C0420732
Finding
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