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Malaria

MedGen UID:
7443
Concept ID:
C0024530
Disease or Syndrome
Synonyms: Fever, Marsh; Fever, Remittent; Infection, Plasmodium; Infections, Plasmodium; Marsh Fever; Paludism; Plasmodium Infection; Plasmodium Infections; Remittent Fever
Modes of inheritance:
not inherited
MedGen UID:
832438
Concept ID:
CN227390
Intellectual Product
Source: Orphanet
Describes a disorder that is not inherited.
not inherited (Orphanet)
SNOMED CT: Malaria (61462000); Paludism (61462000); Plasmodiosis (61462000); Disease due to Plasmodiidae (105649009); Disease caused by Plasmodiidae (105649009); Malarial fever (248437004)
 
Orphanet: ORPHA673

Definition

Malaria is a serious disease caused by a parasite. You get it when an infected mosquito bites you. Malaria is a major cause of death worldwide, but it is almost wiped out in the United States. The disease is mostly a problem in developing countries with warm climates. If you travel to these countries, you are at risk. There are four different types of malaria caused by four related parasites. The most deadly type occurs in Africa south of the Sahara Desert. Malaria symptoms include chills, flu-like symptoms, fever, vomiting, diarrhea, and jaundice. A blood test can diagnose it. It can be life-threatening. However, you can treat malaria with drugs. The type of drug depends on which kind of malaria you have and where you were infected. Malaria can be prevented. When traveling to malaria-prone regions. - See your doctor for medicines that protect you . - Wear insect repellent with DEET . - Cover up. - Sleep under mosquito netting . Centers for Disease Control and Prevention.  [from MedlinePlus]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalaria
Follow this link to review classifications for Malaria in Orphanet.

Recent clinical studies

Etiology

Ingabire CM, Hakizimana E, Kateera F, Rulisa A, Van Den Borne B, Nieuwold I, Muvunyi C, Koenraadt CJ, Van Vugt M, Mutesa L, Alaii J
Malar J 2016 Dec 16;15(1):594. doi: 10.1186/s12936-016-1645-3. PMID: 27986094Free PMC Article
Mathanga DP, Tembo AK, Mzilahowa T, Bauleni A, Mtimaukenena K, Taylor TE, Valim C, Walker ED, Wilson ML
Malar J 2016 Dec 8;15(1):590. doi: 10.1186/s12936-016-1623-9. PMID: 27931234Free PMC Article
Pongvongsa T, Nonaka D, Iwagami M, Nakatsu M, Phongmany P, Nishimoto F, Kobayashi J, Hongvanthon B, Brey PT, Moji K, Mita T, Kano S
Malar J 2016 Oct 18;15(1):508. doi: 10.1186/s12936-016-1552-7. PMID: 27756391Free PMC Article
Kefyalew T, Kebede Z, Getachew D, Mukanga D, Awano T, Tekalegne A, Batisso E, Edossa W, Mekonnen E, Tibenderana J, Baba ES, Shumba C, Nankabirwa JI, Hamade P
Malar J 2016 Oct 18;15(1):507. doi: 10.1186/s12936-016-1561-6. PMID: 27756301Free PMC Article
Orish VN, Ansong JY, Onyeabor OS, Sanyaolu AO, Oyibo WA, Iriemenam NC
Trop Doct 2016 Oct;46(4):191-198. Epub 2016 Jan 5 doi: 10.1177/0049475515622861. PMID: 26738767

Diagnosis

Raman J, Morris N, Frean J, Brooke B, Blumberg L, Kruger P, Mabusa A, Raswiswi E, Shandukani B, Misani E, Groepe MA, Moonasar D
Malar J 2016 Aug 27;15(1):438. doi: 10.1186/s12936-016-1497-x. PMID: 27567642Free PMC Article
Diallo MA, Badiane AS, Diongue K, Deme A, Lucchi NW, Gaye M, Ndiaye T, Ndiaye M, Sene LK, Diop A, Gaye A, Ndiaye YD, Samb D, Yade MS, Ndir O, Udhayakumar V, Ndiaye D
Malar J 2016 Aug 24;15(1):429. doi: 10.1186/s12936-016-1485-1. PMID: 27557982Free PMC Article
Swana EK, Makan GY, Mukeng CK, Mupumba HI, Kalaba GM, Luboya ON, Bangs MJ
Malar J 2016 Aug 15;15(1):413. doi: 10.1186/s12936-016-1475-3. PMID: 27527707Free PMC Article
Lohfeld L, Kangombe-Ngwenya T, Winters AM, Chisha Z, Hamainza B, Kamuliwo M, Miller JM, Burns M, Bridges DJ
Malar J 2016 Aug 8;15(1):400. doi: 10.1186/s12936-016-1455-7. PMID: 27502213Free PMC Article
Orish VN, Ansong JY, Onyeabor OS, Sanyaolu AO, Oyibo WA, Iriemenam NC
Trop Doct 2016 Oct;46(4):191-198. Epub 2016 Jan 5 doi: 10.1177/0049475515622861. PMID: 26738767

Therapy

Gupta P, Narang M, Gomber S, Saha R
Paediatr Int Child Health 2017 May;37(2):139-143. Epub 2016 Jul 26 doi: 10.1080/20469047.2016.1209883. PMID: 27458993
Kefyalew T, Kebede Z, Getachew D, Mukanga D, Awano T, Tekalegne A, Batisso E, Edossa W, Mekonnen E, Tibenderana J, Baba ES, Shumba C, Nankabirwa JI, Hamade P
Malar J 2016 Oct 18;15(1):507. doi: 10.1186/s12936-016-1561-6. PMID: 27756301Free PMC Article
Diallo MA, Badiane AS, Diongue K, Deme A, Lucchi NW, Gaye M, Ndiaye T, Ndiaye M, Sene LK, Diop A, Gaye A, Ndiaye YD, Samb D, Yade MS, Ndir O, Udhayakumar V, Ndiaye D
Malar J 2016 Aug 24;15(1):429. doi: 10.1186/s12936-016-1485-1. PMID: 27557982Free PMC Article
Regules JA, Cicatelli SB, Bennett JW, Paolino KM, Twomey PS, Moon JE, Kathcart AK, Hauns KD, Komisar JL, Qabar AN, Davidson SA, Dutta S, Griffith ME, Magee CD, Wojnarski M, Livezey JR, Kress AT, Waterman PE, Jongert E, Wille-Reece U, Volkmuth W, Emerling D, Robinson WH, Lievens M, Morelle D, Lee CK, Yassin-Rajkumar B, Weltzin R, Cohen J, Paris RM, Waters NC, Birkett AJ, Kaslow DC, Ballou WR, Ockenhouse CF, Vekemans J
J Infect Dis 2016 Sep 1;214(5):762-71. Epub 2016 Jun 13 doi: 10.1093/infdis/jiw237. PMID: 27296848
Orish VN, Ansong JY, Onyeabor OS, Sanyaolu AO, Oyibo WA, Iriemenam NC
Trop Doct 2016 Oct;46(4):191-198. Epub 2016 Jan 5 doi: 10.1177/0049475515622861. PMID: 26738767

Prognosis

Gupta P, Narang M, Gomber S, Saha R
Paediatr Int Child Health 2017 May;37(2):139-143. Epub 2016 Jul 26 doi: 10.1080/20469047.2016.1209883. PMID: 27458993
Ingabire CM, Hakizimana E, Kateera F, Rulisa A, Van Den Borne B, Nieuwold I, Muvunyi C, Koenraadt CJ, Van Vugt M, Mutesa L, Alaii J
Malar J 2016 Dec 16;15(1):594. doi: 10.1186/s12936-016-1645-3. PMID: 27986094Free PMC Article
Mathanga DP, Tembo AK, Mzilahowa T, Bauleni A, Mtimaukenena K, Taylor TE, Valim C, Walker ED, Wilson ML
Malar J 2016 Dec 8;15(1):590. doi: 10.1186/s12936-016-1623-9. PMID: 27931234Free PMC Article
Pongvongsa T, Nonaka D, Iwagami M, Nakatsu M, Phongmany P, Nishimoto F, Kobayashi J, Hongvanthon B, Brey PT, Moji K, Mita T, Kano S
Malar J 2016 Oct 18;15(1):508. doi: 10.1186/s12936-016-1552-7. PMID: 27756391Free PMC Article
Swana EK, Makan GY, Mukeng CK, Mupumba HI, Kalaba GM, Luboya ON, Bangs MJ
Malar J 2016 Aug 15;15(1):413. doi: 10.1186/s12936-016-1475-3. PMID: 27527707Free PMC Article

Clinical prediction guides

Parsel SM, Gustafson SA, Friedlander E, Shnyra AA, Adegbulu AJ, Liu Y, Parrish NM, Jamal SA, Lofthus E, Ayuk L, Awasom C, Henry CJ, McArthur CP
Infect Dis Poverty 2017 Apr 4;6(1):32. doi: 10.1186/s40249-017-0251-0. PMID: 28372570Free PMC Article
Gupta P, Narang M, Gomber S, Saha R
Paediatr Int Child Health 2017 May;37(2):139-143. Epub 2016 Jul 26 doi: 10.1080/20469047.2016.1209883. PMID: 27458993
Ingabire CM, Hakizimana E, Kateera F, Rulisa A, Van Den Borne B, Nieuwold I, Muvunyi C, Koenraadt CJ, Van Vugt M, Mutesa L, Alaii J
Malar J 2016 Dec 16;15(1):594. doi: 10.1186/s12936-016-1645-3. PMID: 27986094Free PMC Article
Pongvongsa T, Nonaka D, Iwagami M, Nakatsu M, Phongmany P, Nishimoto F, Kobayashi J, Hongvanthon B, Brey PT, Moji K, Mita T, Kano S
Malar J 2016 Oct 18;15(1):508. doi: 10.1186/s12936-016-1552-7. PMID: 27756391Free PMC Article
Swana EK, Makan GY, Mukeng CK, Mupumba HI, Kalaba GM, Luboya ON, Bangs MJ
Malar J 2016 Aug 15;15(1):413. doi: 10.1186/s12936-016-1475-3. PMID: 27527707Free PMC Article

Recent systematic reviews

Hopkins H, Bruxvoort KJ, Cairns ME, Chandler CI, Leurent B, Ansah EK, Baiden F, Baltzell KA, Björkman A, Burchett HE, Clarke SE, DiLiberto DD, Elfving K, Goodman C, Hansen KS, Kachur SP, Lal S, Lalloo DG, Leslie T, Magnussen P, Jefferies LM, Mårtensson A, Mayan I, Mbonye AK, Msellem MI, Onwujekwe OE, Owusu-Agyei S, Reyburn H, Rowland MW, Shakely D, Vestergaard LS, Webster J, Wiseman VL, Yeung S, Schellenberg D, Staedke SG, Whitty CJ
BMJ 2017 Mar 29;356:j1054. PMID: 28356302Free PMC Article
Koukouikila-Koussounda F, Ntoumi F
Malar J 2016 Dec 23;15(1):598. doi: 10.1186/s12936-016-1617-7. PMID: 28010728Free PMC Article
Shretta R, Avanceña AL, Hatefi A
Malar J 2016 Dec 12;15(1):593. doi: 10.1186/s12936-016-1635-5. PMID: 27955665Free PMC Article
Frederick J, Saint Jean Y, Lemoine JF, Dotson EM, Mace KE, Chang M, Slutsker L, Le Menach A, Beier JC, Eisele TP, Okech BA, Beau de Rochars VM, Carter KH, Keating J, Impoinvil DE
Malar J 2016 Jul 22;15(1):376. doi: 10.1186/s12936-016-1436-x. PMID: 27443992Free PMC Article
van Eijk AM, Ramanathapuram L, Sutton PL, Kanagaraj D, Sri Lakshmi Priya G, Ravishankaran S, Asokan A, Tandel N, Patel A, Desai N, Singh R, Sullivan SA, Carlton JM, Srivastava HC, Eapen A
Malar J 2016 Feb 6;15:67. doi: 10.1186/s12936-016-1120-1. PMID: 26852118Free PMC Article

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