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Items: 16

1.

Phenytoin

An anticonvulsant that is used to treat a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its many adverse effects and interactions with other drugs. [from MeSH]

MedGen UID:
19249
Concept ID:
C0031507
Organic Chemical; Pharmacologic Substance
2.

Butylated Hydroxyanisole

Mixture of 2- and 3-tert-butyl-4-methoxyphenols that is used as an antioxidant in foods, cosmetics, and pharmaceuticals. [from MeSH]

MedGen UID:
14262
Concept ID:
C0006506
Hazardous or Poisonous Substance; Organic Chemical; Pharmacologic Substance
3.

Miconazole

An imidazole antifungal agent that is used topically and by intravenous infusion. [from MeSH]

MedGen UID:
7624
Concept ID:
C0025942
Organic Chemical; Pharmacologic Substance
4.

Alcohol

A class of compounds where a hydroxyl (OH) group is attached to single bonded hydrocarbons. Alcohols are classified according to the position of the carbon atom with the attached hydroxyl group (i.e. primary alcohols are alcohols with the OH group attached to the primary carbon atom, C1). Uses include solvents, astringents, and anti-infective activity. [from NCI]

MedGen UID:
1400
Concept ID:
C0001975
Organic Chemical; Pharmacologic Substance
5.

Amyotrophy, hereditary neuralgic

Hereditary neuralgic amyotrophy (HNA) is characterized by sudden onset of severe, non-abating pain in the shoulder girdle and/or the upper limb and amyotrophy (muscle wasting or atrophy) that typically develops within two weeks of the onset of severe pain. Other sites may also be involved in an attack; sensory symptoms, present in the majority of affected individuals, can include hypoesthesia (decreased sensation) and paresthesias. Onset is typically in the second or third decade (median age 28 years). Although attacks appear to become less frequent with age, residual deficits accumulate with subsequent attacks. In some families, non-neurologic findings (characteristic craniofacial features, bifid uvula or cleft palate, short stature, and/or partial syndactyly of the fingers or toes) are present. [from GeneReviews]

MedGen UID:
320318
Concept ID:
C1834304
Disease or Syndrome
6.

Oxidation

The process of oxidizing; the addition of oxygen to a compound accompanied by a loss of electrons. [from NCI]

MedGen UID:
18242
Concept ID:
C0030011
Molecular Function
7.

Colme

MedGen UID:
306133
Concept ID:
C1456819
Inorganic Chemical; Pharmacologic Substance
8.

Macrolide

A term used to describe a chemical structure of a compound containing a large lactone ring, usually with a 14 or 16-membered ring structure. The prototypical compounds within the macrolide class are the erythromycin-based antibiotics; however, many compounds with this chemical structure are being developed for other diseases. [from NCI]

MedGen UID:
129193
Concept ID:
C0282563
Organic Chemical; Pharmacologic Substance
9.

Oxygen

An element with atomic symbol O, atomic number 8, and atomic weight 16. [from NCI]

MedGen UID:
45267
Concept ID:
C0030054
Biologically Active Substance; Element, Ion, or Isotope; Pharmacologic Substance
10.

Oxidation-reduction

A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471). [from MeSH]

MedGen UID:
18243
Concept ID:
C0030012
Molecular Function
11.

Temposil

MedGen UID:
11733
Concept ID:
C0039498
Inorganic Chemical; Pharmacologic Substance
12.

Abstem

MedGen UID:
7819
Concept ID:
C0000855
Inorganic Chemical; Pharmacologic Substance
13.

Adenine Nucleotides

condensation product of adenosine and phosphoric acid; a nucleotide found among the hydrolysis products of all nucleic acids. [from CRISP]

MedGen UID:
120
Concept ID:
C0001413
Biologically Active Substance; Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
14.

Tenox BHA

MedGen UID:
162871
Concept ID:
C0795767
Organic Chemical; Pharmacologic Substance
15.

Nipantiox 1-F

MedGen UID:
162768
Concept ID:
C0795768
Organic Chemical; Pharmacologic Substance
16.

Citrated calcium carbimide

MedGen UID:
40322
Concept ID:
C0008856
Inorganic Chemical; Pharmacologic Substance
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