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Influenza

MedGen UID:
9466
Concept ID:
C0021400
Disease or Syndrome
Synonyms: Flu, Human; Grippe; Human Flu; Human Influenza; Human Influenzas; Influenza in Human; Influenza in Humans; Influenza, Human; Influenzas; Influenzas, Human
SNOMED CT: Influenza (6142004); Flu (6142004); Grippe (6142004)
 
Gene (location): IFITM3 (11p15.5)
OMIM®: 614680

Recent clinical studies

Etiology

Pelat C, Bonmarin I, Ruello M, Fouillet A, Caserio-Schönemann C, Levy-Bruhl D, Le Strat Y; Regional Influenza study group.
Euro Surveill 2017 Aug 10;22(32) doi: 10.2807/1560-7917.ES.2017.22.32.30593. PMID: 28816649
Li H, Yang SG, Gu L, Zhang Y, Yan XX, Liang ZA, Zhang W, Jia HY, Chen W, Liu M, Yu KJ, Xue CX, Hu K, Zou Q, Li LJ, Cao B, Wang C; National Influenza A(H1N1)pdm09 Clinical Investigation Group of China.
Influenza Other Respir Viruses 2017 Jul;11(4):345-354. Epub 2017 Jun 9 doi: 10.1111/irv.12456. PMID: 28464462Free PMC Article
Saha S, Chadha M, Shu Y; Group of Asian Researchers on Influenza (GARI).
Influenza Other Respir Viruses 2016 May;10(3):176-84. Epub 2016 Feb 5 doi: 10.1111/irv.12372. PMID: 26781162Free PMC Article
Fragaszy E, Ishola DA, Brown IH, Enstone J, Nguyen-Van-Tam JS, Simons R, Tucker AW, Wieland B, Williamson SM, Hayward AC; Flu Watch Group., Wood JL; Combating Swine Influenza (COSI) Consortium.
Influenza Other Respir Viruses 2016 Jul;10(4):291-300. Epub 2016 Jan 29 doi: 10.1111/irv.12364. PMID: 26611769Free PMC Article
Tinoco YO, Azziz-Baumgartner E, Rázuri H, Kasper MR, Romero C, Ortiz E, Gomez J, Widdowson MA, Uyeki TM, Gilman RH, Bausch DG, Montgomery JM; Peru Influenza Cohorts Working Group.
Influenza Other Respir Viruses 2016 Jul;10(4):301-9. Epub 2016 Jan 29 doi: 10.1111/irv.12357. PMID: 26547629Free PMC Article

Diagnosis

Belser JA, Creager HM, Zeng H, Maines TR, Tumpey TM
J Infect Dis 2017 Sep 15;216(suppl_4):S508-S511. doi: 10.1093/infdis/jiw559. PMID: 28934452Free PMC Article
Pelat C, Bonmarin I, Ruello M, Fouillet A, Caserio-Schönemann C, Levy-Bruhl D, Le Strat Y; Regional Influenza study group.
Euro Surveill 2017 Aug 10;22(32) doi: 10.2807/1560-7917.ES.2017.22.32.30593. PMID: 28816649
Li ZN, Trost JF, Weber KM, LeMasters EH, Nasreen S, Esfandiari J, Gunasekera AH, McCausland M, Sturm-Ramirez K, Wrammert J, Gregory S, Veguilla V, Stevens J, Miller JD, Katz JM, Levine MZ
Influenza Other Respir Viruses 2017 May;11(3):289-297. Epub 2017 Apr 5 doi: 10.1111/irv.12449. PMID: 28207986Free PMC Article
Huai Y, Guan X, Liu S, Uyeki TM, Jiang H, Klena J, Huang J, Chen M, Peng Y, Yang H, Luo J, Zheng J, Peng Z, Huo X, Xiao L, Chen H, Zhang Y, Xing X, Feng L, Hu DJ, Yu H, Zhan F, Varma JK
Influenza Other Respir Viruses 2017 Mar;11(2):148-156. Epub 2016 Sep 20 doi: 10.1111/irv.12419. PMID: 27465959Free PMC Article
Tinoco YO, Azziz-Baumgartner E, Rázuri H, Kasper MR, Romero C, Ortiz E, Gomez J, Widdowson MA, Uyeki TM, Gilman RH, Bausch DG, Montgomery JM; Peru Influenza Cohorts Working Group.
Influenza Other Respir Viruses 2016 Jul;10(4):301-9. Epub 2016 Jan 29 doi: 10.1111/irv.12357. PMID: 26547629Free PMC Article

Therapy

Havers FP, Campbell AP, Uyeki TM, Fry AM
J Infect Dis 2017 Sep 15;216(suppl_4):S575-S580. doi: 10.1093/infdis/jix065. PMID: 28934460
Andersen TK, Zhou F, Cox R, Bogen B, Grødeland G
J Virol 2017 Dec 1;91(23) Epub 2017 Nov 14 doi: 10.1128/JVI.01340-17. PMID: 28931687Free PMC Article
Li H, Yang SG, Gu L, Zhang Y, Yan XX, Liang ZA, Zhang W, Jia HY, Chen W, Liu M, Yu KJ, Xue CX, Hu K, Zou Q, Li LJ, Cao B, Wang C; National Influenza A(H1N1)pdm09 Clinical Investigation Group of China.
Influenza Other Respir Viruses 2017 Jul;11(4):345-354. Epub 2017 Jun 9 doi: 10.1111/irv.12456. PMID: 28464462Free PMC Article
Koszalka P, Tilmanis D, Hurt AC
Influenza Other Respir Viruses 2017 May;11(3):240-246. Epub 2017 Feb 28 doi: 10.1111/irv.12446. PMID: 28146320Free PMC Article
Cowling BJ, Kwan MY, Wong JS, Feng S, Leung CW, Chan EL, Chan KH, Ng TK, To WK, Peiris MJ, Chiu SS
Influenza Other Respir Viruses 2017 Jan;11(1):61-65. Epub 2016 Oct 14 doi: 10.1111/irv.12399. PMID: 27313064Free PMC Article

Prognosis

Kamigaki T, Aldey PP, Mercado ES, Tan AG, Javier JB, Lupisan SP, Oshitani H, Tallo VL
Influenza Other Respir Viruses 2017 Jul;11(4):311-318. Epub 2017 May 3 doi: 10.1111/irv.12453. PMID: 28371393Free PMC Article
Thomas M, Mani RS, Philip M, Adhikary R, Joshi S, Revadi SS, Buggi S, Desai A, Vasanthapuram R
J Med Virol 2017 Aug;89(8):1373-1381. Epub 2017 Mar 3 doi: 10.1002/jmv.24781. PMID: 28198028
Huai Y, Guan X, Liu S, Uyeki TM, Jiang H, Klena J, Huang J, Chen M, Peng Y, Yang H, Luo J, Zheng J, Peng Z, Huo X, Xiao L, Chen H, Zhang Y, Xing X, Feng L, Hu DJ, Yu H, Zhan F, Varma JK
Influenza Other Respir Viruses 2017 Mar;11(2):148-156. Epub 2016 Sep 20 doi: 10.1111/irv.12419. PMID: 27465959Free PMC Article
Gonçalves AR, Iten A, Suter-Boquete P, Schibler M, Kaiser L, Cordey S
Influenza Other Respir Viruses 2017 Jan;11(1):41-47. Epub 2016 Aug 31 doi: 10.1111/irv.12417. PMID: 27441401Free PMC Article
Voltersvik P, Aqrawi LA, Dudman S, Hungnes O; Norwegian Lung Pathology Group., Bostad L, Brokstad KA, Cox RJ
Influenza Other Respir Viruses 2016 Nov;10(6):525-531. Epub 2016 Sep 1 doi: 10.1111/irv.12410. PMID: 27413002Free PMC Article

Clinical prediction guides

Pulit-Penaloza JA, Simpson N, Yang H, Creager HM, Jones J, Carney P, Belser JA, Yang G, Chang J, Zeng H, Thor S, Jang Y, Killian ML, Jenkins-Moore M, Janas-Martindale A, Dubovi E, Wentworth DE, Stevens J, Tumpey TM, Davis CT, Maines TR
J Infect Dis 2017 Sep 15;216(suppl_4):S499-S507. doi: 10.1093/infdis/jiw620. PMID: 28934454Free PMC Article
Belser JA, Creager HM, Zeng H, Maines TR, Tumpey TM
J Infect Dis 2017 Sep 15;216(suppl_4):S508-S511. doi: 10.1093/infdis/jiw559. PMID: 28934452Free PMC Article
Glatman-Freedman A, Drori Y, Beni SA, Friedman N, Pando R, Sefty H, Tal I, McCauley J, Rahav G, Keller N, Shohat T, Mendelson E, Hindiyeh M, Mandelboim M
J Clin Virol 2017 Aug;93:71-75. Epub 2017 Jun 4 doi: 10.1016/j.jcv.2017.05.020. PMID: 28672275Free PMC Article
Li H, Yang SG, Gu L, Zhang Y, Yan XX, Liang ZA, Zhang W, Jia HY, Chen W, Liu M, Yu KJ, Xue CX, Hu K, Zou Q, Li LJ, Cao B, Wang C; National Influenza A(H1N1)pdm09 Clinical Investigation Group of China.
Influenza Other Respir Viruses 2017 Jul;11(4):345-354. Epub 2017 Jun 9 doi: 10.1111/irv.12456. PMID: 28464462Free PMC Article
Gonçalves AR, Iten A, Suter-Boquete P, Schibler M, Kaiser L, Cordey S
Influenza Other Respir Viruses 2017 Jan;11(1):41-47. Epub 2016 Aug 31 doi: 10.1111/irv.12417. PMID: 27441401Free PMC Article

Recent systematic reviews

Buchan SA, Hottes TS, Rosella LC, Crowcroft NS, Tran D, Kwong JC
Influenza Other Respir Viruses 2016 Nov;10(6):444-454. Epub 2016 Aug 18 doi: 10.1111/irv.12400. PMID: 27311404Free PMC Article
Klein EY, Monteforte B, Gupta A, Jiang W, May L, Hsieh YH, Dugas A
Influenza Other Respir Viruses 2016 Sep;10(5):394-403. Epub 2016 Jun 24 doi: 10.1111/irv.12398. PMID: 27232677Free PMC Article
Lafond KE, Nair H, Rasooly MH, Valente F, Booy R, Rahman M, Kitsutani P, Yu H, Guzman G, Coulibaly D, Armero J, Jima D, Howie SR, Ampofo W, Mena R, Chadha M, Sampurno OD, Emukule GO, Nurmatov Z, Corwin A, Heraud JM, Noyola DE, Cojocaru R, Nymadawa P, Barakat A, Adedeji A, von Horoch M, Olveda R, Nyatanyi T, Venter M, Mmbaga V, Chittaganpitch M, Nguyen TH, Theo A, Whaley M, Azziz-Baumgartner E, Bresee J, Campbell H, Widdowson MA; Global Respiratory Hospitalizations—Influenza Proportion Positive (GRIPP) Working Group.
PLoS Med 2016 Mar;13(3):e1001977. Epub 2016 Mar 24 doi: 10.1371/journal.pmed.1001977. PMID: 27011229Free PMC Article
Hirve S, Lambach P, Paget J, Vandemaele K, Fitzner J, Zhang W
Influenza Other Respir Viruses 2016 Jul;10(4):254-67. Epub 2016 May 26 doi: 10.1111/irv.12374. PMID: 26842617Free PMC Article
Muthuri SG, Venkatesan S, Myles PR, Leonardi-Bee J, Lim WS, Al Mamun A, Anovadiya AP, Araújo WN, Azziz-Baumgartner E, Báez C, Bantar C, Barhoush MM, Bassetti M, Beovic B, Bingisser R, Bonmarin I, Borja-Aburto VH, Cao B, Carratala J, Cuezzo MR, Denholm JT, Dominguez SR, Duarte PA, Dubnov-Raz G, Echavarria M, Fanella S, Fraser J, Gao Z, Gérardin P, Giannella M, Gubbels S, Herberg J, Higuera Iglesias AL, Hoeger PH, Hoffmann M, Hu X, Islam QT, Jiménez MF, Kandeel A, Keijzers G, Khalili H, Khandaker G, Knight M, Kusznierz G, Kuzman I, Kwan AM, Lahlou Amine I, Langenegger E, Lankarani KB, Leo YS, Linko R, Liu P, Madanat F, Manabe T, Mayo-Montero E, McGeer A, Memish ZA, Metan G, Mikić D, Mohn KG, Moradi A, Nymadawa P, Ozbay B, Ozkan M, Parekh D, Paul M, Poeppl W, Polack FP, Rath BA, Rodríguez AH, Siqueira MM, Skręt-Magierło J, Talarek E, Tang JW, Torres A, Törün SH, Tran D, Uyeki TM, van Zwol A, Vaudry W, Velyvyte D, Vidmar T, Zarogoulidis P; PRIDE Consortium Investigators., Nguyen-Van-Tam JS
Influenza Other Respir Viruses 2016 May;10(3):192-204. Epub 2016 Feb 1 doi: 10.1111/irv.12363. PMID: 26602067Free PMC Article

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