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Items: 8

1.

Purpura

A small blood vessel hemorrhage into the skin and/or mucous membranes. Newer lesions appear reddish in color. Older lesions are usually a darker purple color and eventually become a brownish-yellow color. [from NCI]

MedGen UID:
19584
Concept ID:
C0034150
Disease or Syndrome; Finding
2.

Nephritis

Inflammation of any part of the KIDNEY. [from MeSH]

MedGen UID:
14328
Concept ID:
C0027697
Disease or Syndrome
3.

Henoch-Schönlein Purpura Nephritis

Glomerulonephritis in the context of Henoch-Schönlein purpura.(NICHD) [from NCI]

MedGen UID:
885994
Concept ID:
C2721603
Disease or Syndrome
4.

Immunoglobulin A vasculitis

Schönlein-Henoch purpura (SHP) is a systemic IgA vasculitis that affects small vessels. It is characterized by skin purpura, arthritis, and abdominal and/or renal involvement. [from ORDO]

MedGen UID:
799309
Concept ID:
CN205724
Finding
5.

Improved

Condition changed and/or recovered [from CCC]

MedGen UID:
512204
Concept ID:
C0184511
Finding
6.

Henoch-schönlein purpura

A systemic non-thrombocytopenic purpura caused by HYPERSENSITIVITY VASCULITIS and deposition of IGA-containing IMMUNE COMPLEXES within the blood vessels throughout the body, including those in the kidney (KIDNEY GLOMERULUS). Clinical symptoms include URTICARIA; ERYTHEMA; ARTHRITIS; GASTROINTESTINAL HEMORRHAGE; and renal involvement. Most cases are seen in children after acute upper respiratory infections. [from MeSH]

MedGen UID:
48265
Concept ID:
C0034152
Disease or Syndrome
7.

Hydrocortisone sodium succinate

The sodium salt of hydrocortisone succinate with glucocorticoid property. Hydrocortisone sodium succinate is chemically similar to the endogenous hormone that stimulates anti-inflammatory and immunosuppressive activities, in addition to exhibiting minor mineralocorticoid effects. This agent binds to intracellular glucocorticoid receptors and is translocated into the nucleus, where it initiates the transcription of glucocorticoid-responsive genes, such as various cytokines and lipocortins. Lipocortins inhibit phospholipase A2, thereby blocking the release of arachidonic acid from membrane phospholipids and preventing the synthesis of prostaglandins and leukotrienes, both potent mediators of inflammation. [from NCI]

MedGen UID:
166955
Concept ID:
C0770560
Organic Chemical; Pharmacologic Substance
8.

Sodium succinate

MedGen UID:
55370
Concept ID:
C0142928
Organic Chemical; Pharmacologic Substance
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