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1.

Ganglioglioma

A well differentiated, slow growing neuroepithelial neoplasm composed of neoplastic, mature ganglion cells and neoplastic glial cells. Some gangliogliomas show anaplastic features in their glial component and are considered to be WHO grade III. Rare cases of newly diagnosed gangliogliomas with grade IV (glioblastoma) changes in the glial component have also been reported. (Adapted from WHO) [from NCI]

MedGen UID:
60216
Concept ID:
C0206716
Neoplastic Process
2.

Astrocytoma, anaplastic

A diffusely infiltrating, WHO grade III astrocytoma with focal or dispersed anaplasia, and a marked proliferative potential. It may arise from a low-grade astrocytoma, but it can also be diagnosed at first biopsy, without indication of a less malignant precursor lesion. It has an intrinsic tendency for malignant progression to glioblastoma. (WHO) [from NCI]

MedGen UID:
137784
Concept ID:
C0334579
Neoplastic Process
3.

Delayed speech acquisition

MedGen UID:
66827
Concept ID:
C0241210
Mental or Behavioral Dysfunction
4.

Cataract

A cataract is an opacity or clouding that develops in the crystalline lens of the eye or in its capsule. [from HPO]

MedGen UID:
39462
Concept ID:
C0086543
Acquired Abnormality; Finding; Finding
5.

Astrocytoma

A glial tumor of the brain or spinal cord showing astrocytic differentiation. It includes the following clinicopathological entities: pilocytic astrocytoma, diffuse astrocytoma, anaplastic astrocytoma, pleomorphic xanthoastrocytoma, subependymal giant cell astrocytoma, and glioblastoma. [from NCI]

MedGen UID:
438
Concept ID:
C0004114
Neoplastic Process
6.

Brain neoplasm

MedGen UID:
910838
Concept ID:
CN241425
Finding
7.

Neurologic

MedGen UID:
880863
Concept ID:
CN236425
Finding
8.

Delay

MedGen UID:
879911
Concept ID:
CN235300
Finding
9.

Astrocytoma

Astrocytoma is a neoplasm of the central nervous system derived from astrocytes. Astrocytes are a type of glial cell, and thus astrocytoma is a subtype of glioma. [from HPO]

MedGen UID:
506296
Concept ID:
CN008457
Finding
10.

Speech delay

MedGen UID:
472108
Concept ID:
CN130030
Disease or Syndrome
11.

Cataract

MedGen UID:
368085
Concept ID:
C1962983
Finding
12.

Congenital cataract

MedGen UID:
330823
Concept ID:
C1842324
13.

Neoplasm

A malignant tumor at the original site of growth. [from NCI]

MedGen UID:
227011
Concept ID:
C1306459
Neoplastic Process
14.

Anaplastic Ganglioglioma

A WHO grade III neuroepithelial neoplasm composed of neoplastic, mature ganglion cells and anaplastic glial cells. The anaplastic changes in the glial component and high MIB-1 and TP53 labeling indices may indicate aggressive behavior. However, the correlation of histological anaplasia with clinical outcome is inconsistent. (Adapted from WHO) [from NCI]

MedGen UID:
140906
Concept ID:
C0431112
Neoplastic Process
15.

Delayed speech and language development

A degree of language development that is significantly below the norm for a child of a specified age. [from HPO]

MedGen UID:
105318
Concept ID:
C0454644
Finding
16.

Cataract, congenital

A congenital cataract. [from HPO]

MedGen UID:
3202
Concept ID:
C0009691
Congenital Abnormality
17.

Epithelial Neoplasm

A benign or malignant neoplasm that arises from and is composed of epithelial cells. This category include adenomas, papillomas, and carcinomas. [from NCI]

MedGen UID:
277963
Concept ID:
C1368683
Neoplastic Process
18.

Duplication of chromosome

An aberration in which an extra chromosome or a chromosomal segment is made. [from MeSH]

MedGen UID:
275730
Concept ID:
C1516516
Cell or Molecular Dysfunction
19.

Ganglioglioma, Intracranial

MedGen UID:
199710
Concept ID:
C0751679
Neoplastic Process
20.

Experimental Organism Benign Ganglioglioma

A benign neoplasm comprised of neoplastic ganglion and glial cells. [from NCI]

MedGen UID:
199709
Concept ID:
C0751678
Neoplastic Process
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