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Items: 6

1.

Asthma

A chronic respiratory disease manifested as difficulty breathing due to the narrowing of bronchial passageways. [from NCI]

MedGen UID:
2109
Concept ID:
C0004096
Disease or Syndrome
2.

Bronchomoniliasis

MedGen UID:
737485
Concept ID:
C1622369
Disease or Syndrome
3.

Cheese-makers asthma

MedGen UID:
729880
Concept ID:
C1321272
Disease or Syndrome
4.

Meat-wrappers asthma

MedGen UID:
536788
Concept ID:
C0238266
Disease or Syndrome
5.

Asthma

Asthma is characterized by increased responsiveness of the tracheobronchial tree to multiple stimuli, leading to narrowing of the air passages with resultant dyspnea, cough, and wheezing. [from HPO]

MedGen UID:
505101
Concept ID:
CN001900
Finding
6.

Hb SS disease

Sickle cell disease (SCD) is characterized by intermittent vaso-occlusive events and chronic hemolytic anemia. Vaso-occlusive events result in tissue ischemia leading to acute and chronic pain as well as organ damage that can affect any organ system, including the bones, spleen, liver, brain, lungs, kidneys, and joints. Dactylitis (pain and/or swelling of the hands or feet) is often the earliest manifestation of SCD. In children, the spleen can become engorged with blood cells in a “splenic sequestration.” The spleen is particularly vulnerable to infarction and the majority of individuals with SCD who are not on hydroxyurea or transfusion therapy become functionally asplenic in early childhood, increasing their risk for certain types of bacterial infections. Acute chest syndrome is a major cause of mortality in SCD. Chronic hemolysis can result in varying degrees of anemia, jaundice, cholelithiasis, and delayed growth and sexual maturation. Individuals with the highest rates of hemolysis are predisposed to pulmonary artery hypertension, priapism, and leg ulcers but may be relatively protected from vaso-occlusive pain. [from GTR]

MedGen UID:
287
Concept ID:
C0002895
Disease or Syndrome
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