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Items: 5

1.

Ligand Binding

Ligand Binding is the tight and specific (high affinity) interaction between a small molecule (typically) and a macromolecule (usually protein) that ordinarily results in modification of its function, e.g., antigen-antibody binding, hormone- or neurotransmitter-receptor binding. [from NCI]

MedGen UID:
309303
Concept ID:
C1517880
Molecular Function
2.

cytotoxicity

The adverse effect of some iatrogenic therapies. It is an accepted side effect in radiation therapy where the desired effect is to kill rapidly growing tumor cells. In the killing of tumor cells, other cells that are rapidly growing e.g hair, mucous membranes are also killed. [from NCI]

MedGen UID:
108579
Concept ID:
C0596402
Cell or Molecular Dysfunction
3.

Confusion

Lack of clarity and coherence of thought, perception, understanding, or action. [from HPO]

MedGen UID:
3587
Concept ID:
C0009676
Mental or Behavioral Dysfunction
4.

Neoplasm

A malignant tumor at the original site of growth. [from NCI]

MedGen UID:
227011
Concept ID:
C1306459
Neoplastic Process
5.

Uncertain

A measure of the inherent variability of repeated observation measurements of a quantity including quantities evaluated by statistical methods and by other means. [from NCI]

MedGen UID:
43443
Concept ID:
C0087130
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