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Items: 1 to 20 of 36

1.

Cetuximab

A chimeric monoclonal antibody that functions as an ANTINEOPLASTIC AGENT through its binding to the EPIDERMAL GROWTH FACTOR RECEPTOR, where it prevents the binding and signaling action of cell growth and survival factors. [from MeSH]

MedGen UID:
242381
Concept ID:
C0995188
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
2.

Neoplasm of head and neck

A primary or metastatic malignant neoplasm affecting the head and neck. Representative examples include oral cavity squamous cell carcinoma, laryngeal squamous cell carcinoma, and salivary gland carcinoma. [from NCI]

MedGen UID:
78920
Concept ID:
C0278996
Neoplastic Process
3.

pemetrexed

A guanine-derived ANTINEOPLASTIC AGENT that functions as a NUCLEIC ACID SYNTHESIS INHIBITOR through its binding to, and inhibition of, THYMIDYLATE SYNTHASE. [from MeSH]

MedGen UID:
60499
Concept ID:
C0210657
Organic Chemical; Pharmacologic Substance
4.

Febrile neutropenia

Fever accompanied by a significant reduction in the number of NEUTROPHILS. [from MeSH]

MedGen UID:
152883
Concept ID:
C0746883
Disease or Syndrome
5.

Sepsis

Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK. [from MeSH]

MedGen UID:
69314
Concept ID:
C0243026
Disease or Syndrome
6.

Epidermal growth factor

A 6-kDa polypeptide growth factor initially discovered in mouse submaxillary glands. Human epidermal growth factor was originally isolated from urine based on its ability to inhibit gastric secretion and called urogastrone. Epidermal growth factor exerts a wide variety of biological effects including the promotion of proliferation and differentiation of mesenchymal and EPITHELIAL CELLS. It is synthesized as a transmembrane protein which can be cleaved to release a soluble active form. [from MeSH]

MedGen UID:
66867
Concept ID:
C0242275
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
7.

Duodenal ulcer

A PEPTIC ULCER located in the DUODENUM. [from MeSH]

MedGen UID:
41670
Concept ID:
C0013295
Disease or Syndrome
8.

Ulcer

A circumscribed inflammatory and often suppurating lesion on the skin or an internal mucous surface resulting in necrosis of tissue. [from NCI]

MedGen UID:
22541
Concept ID:
C0041582
Disease or Syndrome
9.

Neutropenic disorder

A decrease in the number of NEUTROPHILS found in the blood. [from MeSH]

MedGen UID:
18030
Concept ID:
C0027947
Disease or Syndrome
10.

Poor prognosis

MedGen UID:
548766
Concept ID:
C0278252
Finding
11.

Neutropenia

A decrease in the number of neutrophils in the peripheral blood. [from NCI]

MedGen UID:
163121
Concept ID:
C0853697
Finding
12.

Grade 3

A morphologic qualifier indicating that a cancerous lesion is poorly differentiated. [from NCI]

MedGen UID:
141532
Concept ID:
C0450094
Finding
13.

Perforating

A hole or opening made through a membrane or other tissue or material. [from NCI]

MedGen UID:
108190
Concept ID:
C0549099
Finding
14.

Mucous inflammation

An INFLAMMATION of the MUCOSA with burning or tingling sensation. It is characterized by atrophy of the squamous EPITHELIUM, vascular damage, inflammatory infiltration, and ulceration. It usually occurs at the mucous lining of the MOUTH, the GASTROINTESTINAL TRACT or the airway due to chemical irritations, CHEMOTHERAPY, or radiation therapy (RADIOTHERAPY). [from MeSH]

MedGen UID:
87165
Concept ID:
C0333355
Pathologic Function
15.

Sepsis

Systemic disease associated with the presence of pathogenic microorganisms or their toxins in the blood. [from MeSH]

MedGen UID:
48626
Concept ID:
C0036690
Disease or Syndrome
16.

Antifolate

A compound with a chemical structure similar to folic acid. Folate antagonists inhibit one or more folate-dependent enzymes, resulting in decreased DNA, RNA and protein synthesis. [from NCI]

MedGen UID:
8877
Concept ID:
C0016411
Pharmacologic Substance
17.

Epithelial Neoplasm

A benign or malignant neoplasm that arises from and is composed of epithelial cells. This category include adenomas, papillomas, and carcinomas. [from NCI]

MedGen UID:
277963
Concept ID:
C1368683
Neoplastic Process
18.

Alimta

MedGen UID:
249025
Concept ID:
C1101816
Organic Chemical; Pharmacologic Substance
19.

Erbitux

MedGen UID:
217485
Concept ID:
C1173436
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
20.

Carcinomatosis

Carcinoma that has spread diffusely to an anatomic site or throughout the body. [from NCI]

MedGen UID:
104704
Concept ID:
C0205699
Neoplastic Process
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