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Ketogenic diet

MedGen UID:
78066
Concept ID:
C0259972
Finding
Synonyms: Diet, Ketogenic; Diets, Ketogenic; Ketogenic Diet; Ketogenic Diets
SNOMED CT: Ketogenic diet (226108007); KD - Ketogenic diet (226108007)
 

Definition

A course of food intake that is high in FATS and low in CARBOHYDRATES. This diet provides sufficient PROTEINS for growth but insufficient amount of carbohydrates for the energy needs of the body. A ketogenic diet generates 80-90% of caloric requirements from fats and the remainder from proteins. [from MeSH]

Recent clinical studies

Etiology

Whiting S, Donner E, RamachandranNair R, Grabowski J, Jetté N, Duque DR
Epilepsy Res 2017 Mar;131:51-57. Epub 2017 Feb 20 doi: 10.1016/j.eplepsyres.2017.01.013. PMID: 28259032
Ozdemir R, Kucuk M, Guzel O, Karadeniz C, Yilmaz U, Mese T
Brain Dev 2016 Oct;38(9):842-7. Epub 2016 Apr 5 doi: 10.1016/j.braindev.2016.03.009. PMID: 27066714
Hussain SA, Shin JH, Shih EJ, Murata KK, Sewak S, Kezele ME, Sankar R, Matsumoto JH
Seizure 2016 Feb;35:59-64. Epub 2016 Jan 9 doi: 10.1016/j.seizure.2016.01.002. PMID: 26803052
Özdemir R, Güzel O, Küçük M, Karadeniz C, Katipoglu N, Yılmaz Ü, Yılmazer MM, Meşe T
Pediatr Neurol 2016 Mar;56:30-34. Epub 2015 Nov 26 doi: 10.1016/j.pediatrneurol.2015.10.017. PMID: 26774551
Lin JJ, Lin KL, Chan OW, Hsia SH, Wang HS; CHEESE Study Group.
Pediatr Neurol 2015 Apr;52(4):442-5. Epub 2014 Dec 31 doi: 10.1016/j.pediatrneurol.2014.12.008. PMID: 25771999

Diagnosis

Cappuccio G, Pinelli M, Alagia M, Donti T, Day-Salvatore DL, Veggiotti P, De Giorgis V, Lunghi S, Vari MS, Striano P, Brunetti-Pierri N, Kennedy AD, Elsea SH
PLoS One 2017;12(9):e0184022. Epub 2017 Sep 29 doi: 10.1371/journal.pone.0184022. PMID: 28961260Free PMC Article
Zahra A, Fath MA, Opat E, Mapuskar KA, Bhatia SK, Ma DC, Rodman SN III, Snyders TP, Chenard CA, Eichenberger-Gilmore JM, Bodeker KL, Ahmann L, Smith BJ, Vollstedt SA, Brown HA, Hejleh TA, Clamon GH, Berg DJ, Szweda LI, Spitz DR, Buatti JM, Allen BG
Radiat Res 2017 Jun;187(6):743-754. Epub 2017 Apr 24 doi: 10.1667/RR14668.1. PMID: 28437190Free PMC Article
Bruce S, Devlin A, Air L, Cook L
Epilepsy Behav 2017 Jan;66:100-104. Epub 2016 Dec 27 doi: 10.1016/j.yebeh.2016.10.001. PMID: 28038385
Ułamek-Kozioł M, Pluta R, Bogucka-Kocka A, Czuczwar SJ
Ann Agric Environ Med 2016 Dec 23;23(4):533-536. doi: 10.5604/12321966.1226841. PMID: 28030918
Caraballo R, Noli D, Cachia P
Epileptic Disord 2015 Jun;17(2):194-7. doi: 10.1684/epd.2015.0741. PMID: 25895661

Therapy

Ashrafi MR, Hosseini SA, Zamani GR, Mohammadi M, Tavassoli A, Badv RS, Heidari M, Karimi P, Malamiri RA
Acta Neurol Belg 2017 Mar;117(1):175-182. Epub 2016 Dec 7 doi: 10.1007/s13760-016-0732-0. PMID: 27928725
Spilioti M, Pavlou E, Gogou M, Katsanika I, Papadopoulou-Alataki E, Grafakou O, Gkampeta A, Dinopoulos A, Evangeliou A
Eur J Paediatr Neurol 2016 Jul;20(4):555-9. Epub 2016 Apr 13 doi: 10.1016/j.ejpn.2016.04.003. PMID: 27117552
Ozdemir R, Kucuk M, Guzel O, Karadeniz C, Yilmaz U, Mese T
Brain Dev 2016 Oct;38(9):842-7. Epub 2016 Apr 5 doi: 10.1016/j.braindev.2016.03.009. PMID: 27066714
Özdemir R, Güzel O, Küçük M, Karadeniz C, Katipoglu N, Yılmaz Ü, Yılmazer MM, Meşe T
Pediatr Neurol 2016 Mar;56:30-34. Epub 2015 Nov 26 doi: 10.1016/j.pediatrneurol.2015.10.017. PMID: 26774551
Moriyama K, Watanabe M, Yamada Y, Shiihara T
Pediatr Neurol 2015 May;52(5):526-8. Epub 2015 Jan 26 doi: 10.1016/j.pediatrneurol.2015.01.009. PMID: 25724370

Prognosis

Ashrafi MR, Hosseini SA, Zamani GR, Mohammadi M, Tavassoli A, Badv RS, Heidari M, Karimi P, Malamiri RA
Acta Neurol Belg 2017 Mar;117(1):175-182. Epub 2016 Dec 7 doi: 10.1007/s13760-016-0732-0. PMID: 27928725
Palmer S, Towne MC, Pearl PL, Pelletier RC, Genetti CA, Shi J, Beggs AH, Agrawal PB, Brownstein CA
Pediatr Neurol 2016 Nov;64:77-79. Epub 2016 Jul 28 doi: 10.1016/j.pediatrneurol.2016.07.012. PMID: 27600546Free PMC Article
Ozdemir R, Kucuk M, Guzel O, Karadeniz C, Yilmaz U, Mese T
Brain Dev 2016 Oct;38(9):842-7. Epub 2016 Apr 5 doi: 10.1016/j.braindev.2016.03.009. PMID: 27066714
Özdemir R, Güzel O, Küçük M, Karadeniz C, Katipoglu N, Yılmaz Ü, Yılmazer MM, Meşe T
Pediatr Neurol 2016 Mar;56:30-34. Epub 2015 Nov 26 doi: 10.1016/j.pediatrneurol.2015.10.017. PMID: 26774551
Sariego-Jamardo A, García-Cazorla A, Artuch R, Castejón E, García-Arenas D, Molero-Luis M, Ormazábal A, Sanmartí FX
Pediatr Neurol 2015 Nov;53(5):422-6. Epub 2015 Aug 8 doi: 10.1016/j.pediatrneurol.2015.07.013. PMID: 26476148

Clinical prediction guides

Moreno B, Crujeiras AB, Bellido D, Sajoux I, Casanueva FF
Endocrine 2016 Dec;54(3):681-690. Epub 2016 Sep 13 doi: 10.1007/s12020-016-1050-2. PMID: 27623967
Palmer S, Towne MC, Pearl PL, Pelletier RC, Genetti CA, Shi J, Beggs AH, Agrawal PB, Brownstein CA
Pediatr Neurol 2016 Nov;64:77-79. Epub 2016 Jul 28 doi: 10.1016/j.pediatrneurol.2016.07.012. PMID: 27600546Free PMC Article
Sariego-Jamardo A, García-Cazorla A, Artuch R, Castejón E, García-Arenas D, Molero-Luis M, Ormazábal A, Sanmartí FX
Pediatr Neurol 2015 Nov;53(5):422-6. Epub 2015 Aug 8 doi: 10.1016/j.pediatrneurol.2015.07.013. PMID: 26476148
Groleau V, Schall JI, Stallings VA, Bergqvist CA
Dev Med Child Neurol 2014 Sep;56(9):898-904. Epub 2014 Apr 20 doi: 10.1111/dmcn.12462. PMID: 24749520Free PMC Article
McNamara NA, Carbone LA, Shellhaas RA
J Child Neurol 2013 Oct;28(10):1233-7. Epub 2012 Sep 21 doi: 10.1177/0883073812459902. PMID: 23001929

Recent systematic reviews

Sofou K, Dahlin M, Hallböök T, Lindefeldt M, Viggedal G, Darin N
J Inherit Metab Dis 2017 Mar;40(2):237-245. Epub 2017 Jan 18 doi: 10.1007/s10545-016-0011-5. PMID: 28101805Free PMC Article
Martin K, Jackson CF, Levy RG, Cooper PN
Cochrane Database Syst Rev 2016 Feb 9;2:CD001903. doi: 10.1002/14651858.CD001903.pub3. PMID: 26859528
Lv M, Zhu X, Wang H, Wang F, Guan W
PLoS One 2014;9(12):e115147. Epub 2014 Dec 11 doi: 10.1371/journal.pone.0115147. PMID: 25502434Free PMC Article
Lemmon ME, Terao NN, Ng YT, Reisig W, Rubenstein JE, Kossoff EH
Dev Med Child Neurol 2012 May;54(5):464-8. Epub 2012 Mar 22 doi: 10.1111/j.1469-8749.2012.04233.x. PMID: 22443637
Levy RG, Cooper PN, Giri P
Cochrane Database Syst Rev 2012 Mar 14;(3):CD001903. doi: 10.1002/14651858.CD001903.pub2. PMID: 22419282

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