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Items: 1 to 20 of 36

1.

Resveratrol

A phytoalexin derived from grapes and other food products with antioxidant and potential chemopreventive activities. Resveratrol induces phase II drug-metabolizing enzymes (anti-initiation activity); mediates anti-inflammatory effects and inhibits cyclooxygenase and hydroperoxidase functions (anti-promotion activity); and induces promyelocytic leukemia cell differentiation (anti-progression activity), thereby exhibiting activities in three major steps of carcinogenesis. This agent may inhibit TNF-induced activation of NF-kappaB in a dose- and time-dependent manner. (NCI05) [from NCI]

MedGen UID:
35162
Concept ID:
C0073096
Organic Chemical; Pharmacologic Substance
2.

Deacetylation

Deacetylation is the covalent chemical or post-translational biochemical removal of an acetyl group(s) from organic compounds. [from NCI]

MedGen UID:
268332
Concept ID:
C1511737
Molecular Function
3.

Lactate

name of an organic chemical [from CHV]

MedGen UID:
87671
Concept ID:
C0376261
Organic Chemical; Pharmacologic Substance
4.

Oxidative Stress

A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products. The damage to biological tissues is caused by superoxide and other free radicals generated by many factors, including exposure to alcohol, medications, trauma, cold, toxins, and radiation or by antimicrobial cellular immunity, metabolic abnormality, or "normal" aging; not synonymous with hypoxia or hyperoxia. Oxidative stress promotes a range of degenerative disorders, including cancer, diabetes, premature aging, Alzheimer's, and many others. [from NCI]

MedGen UID:
66929
Concept ID:
C0242606
Cell or Molecular Dysfunction
5.

UPREG

A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins. [from MeSH]

MedGen UID:
12003
Concept ID:
C0041904
Molecular Function
6.

Acetylation

Acetylation involves the covalent linkage of an acetyl group into an organic molecule. [from NCI]

MedGen UID:
7840
Concept ID:
C0001038
Molecular Function
7.

Mobility

Ability to move purposefully in own environment independently with or without assistive device [from NOC]

MedGen UID:
603859
Concept ID:
C0425245
Finding
8.

Protein Acetylation

The covalent chemical or post-translational biochemical addition of an acetyl group(s) to a peptide or protein. (NCI) [from NCI]

MedGen UID:
311913
Concept ID:
C1521754
Molecular Function
9.

Mitochondrial inheritance

A mode of inheritance that is observed for traits related to a gene encoded on the mitochondrial genome. Because the mitochondrial genome is essentially always maternally inherited, a mitochondrial condition can only be transmitted by females, although the condition can affect both sexes. The proportion of mutant mitochondria can vary (heteroplasmy). [from HPO]

MedGen UID:
165802
Concept ID:
C0887941
Genetic Function
10.

Stress

The negative mental, emotional, and physical reactions that occur when environmental stressors are perceived as exceeding the individual's adaptive capacities. [from NCI]

MedGen UID:
20971
Concept ID:
C0038435
Finding
11.

Adriablastin

MedGen UID:
423645
Concept ID:
C2936928
Organic Chemical; Pharmacologic Substance
12.

Farmiblastina

MedGen UID:
307476
Concept ID:
C1512059
Organic Chemical; Pharmacologic Substance
13.

Onkodox

MedGen UID:
297409
Concept ID:
C1564916
Organic Chemical; Pharmacologic Substance
14.

Ribodoxo

MedGen UID:
289948
Concept ID:
C1564915
Organic Chemical; Pharmacologic Substance
15.

Doxotec

MedGen UID:
289075
Concept ID:
C1564914
Organic Chemical; Pharmacologic Substance
16.

Doxolem

MedGen UID:
268094
Concept ID:
C1512057
Organic Chemical; Pharmacologic Substance
17.

DOXO-CELL

MedGen UID:
268093
Concept ID:
C1512056
Organic Chemical; Pharmacologic Substance
18.

Adrimedac

MedGen UID:
268092
Concept ID:
C1512055
Organic Chemical; Pharmacologic Substance
19.

Molecular Mechanisms of Pharmacological Action

Pharmacological activities at the molecular level of DRUGS and other exogenous compounds that are used to treat DISEASES and affect normal BIOCHEMISTRY. [from MeSH]

MedGen UID:
226255
Concept ID:
C1258062
Molecular Function
20.

Rubex

MedGen UID:
195822
Concept ID:
C0699076
Organic Chemical; Pharmacologic Substance
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