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Items: 6

1.

Somatotropin preparation

A polypeptide that is secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Growth hormone, also known as somatotropin, stimulates mitosis, cell differentiation and cell growth. Species-specific growth hormones have been synthesized. [from MeSH]

MedGen UID:
20836
Concept ID:
C0037663
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
2.

Lipodystrophy

A collection of heterogenous conditions resulting from defective LIPID METABOLISM and characterized by ADIPOSE TISSUE atrophy. Often there is redistribution of body fat resulting in peripheral fat wasting and central adiposity. They include generalized, localized, congenital, and acquired lipodystrophy. [from MeSH]

MedGen UID:
6111
Concept ID:
C0023787
Disease or Syndrome
3.

Hiv

An infection caused by the human immunodeficiency virus. [from NCI]

MedGen UID:
5583
Concept ID:
C0019693
Disease or Syndrome
4.

HIV-Associated Lipodystrophy Syndrome

Defective metabolism leading to fat maldistribution in patients infected with HIV. The etiology appears to be multifactorial and probably involves some combination of infection-induced alterations in metabolism, direct effects of antiretroviral therapy, and patient-related factors. [from MeSH]

MedGen UID:
210205
Concept ID:
C1136321
Disease or Syndrome
5.

Berardinelli-Seip congenital lipodystrophy

Berardinelli-Seip congenital lipodystrophy (BSCL) is usually diagnosed at birth or soon thereafter. Because of the absence of functional adipocytes, lipid is stored in other tissues, including muscle and liver. Affected individuals develop insulin resistance and approximately 25%-35% develop diabetes mellitus between ages 15 and 20 years. Hepatomegaly secondary to hepatic steatosis and skeletal muscle hypertrophy occur in all affected individuals. Hypertrophic cardiomyopathy is reported in 20%-25% of affected individuals and is a significant cause of morbidity from cardiac failure and early mortality. [from GTR]

MedGen UID:
67438
Concept ID:
C0221032
Disease or Syndrome; Finding
6.

Tesamorelin

MedGen UID:
361817
Concept ID:
C1876200
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
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