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Items: 1 to 20 of 39

1.

Carcinogenesis

The process by which normal cells are transformed into cancer cells. [from NCI_NCI-GLOSS]

MedGen UID:
154544
Concept ID:
C0596263
Neoplastic Process
2.

Estrogens

A class of natural or synthetic hormones that binds to a cytoplasmic receptor and initiates translocation of the hormone-receptor complex to the nucleus of target cells of tissues rich in estrogen receptors, including the endometrium, myometrium, oviduct, vagina, fallopian tube, cervix, brain, liver, placenta, ovarian cells, Leydigs cells, kidney, prostate, pancreas, heart, and skin. (NCI) [from NCI]

MedGen UID:
8701
Concept ID:
C0014939
Hormone; Organic Chemical; Pharmacologic Substance
3.

Fulvestrant

A synthetic estrogen receptor antagonist. Unlike tamoxifen (which has partial agonist effects) and the aromatase inhibitors (which reduce the estrogen available to tumor cells), fulvestrant binds competitively to estrogen receptors in breast cancer cells, resulting in estrogen receptor deformation and decreased estrogen binding. In vitro studies indicate that fulvestrant reversibly inhibits the growth of tamoxifen-resistant, estrogen-sensitive, human breast cancer cell lines. (NCI04) [from NCI]

MedGen UID:
182597
Concept ID:
C0935916
Organic Chemical; Pharmacologic Substance
4.

catechol

A chemical originally isolated from a type of mimosa tree. Catechol is used as an astringent, an antiseptic, and in photography, electroplating, and making other chemicals. It can also be man-made. [from NCI_NCI-GLOSS]

MedGen UID:
27059
Concept ID:
C0054858
Organic Chemical; Pharmacologic Substance
5.

Estradiol

a steroid sex hormone [from CHV]

MedGen UID:
4551
Concept ID:
C0014912
Hormone; Organic Chemical; Pharmacologic Substance
6.

Carcinoma

A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas (NCI Thesaurus). [from HPO]

MedGen UID:
2867
Concept ID:
C0007097
Neoplastic Process
7.

Carcinoma

MedGen UID:
910818
Concept ID:
CN241453
Finding
8.

Epithelioma, malignant

MedGen UID:
639977
Concept ID:
C0553707
Neoplastic Process
9.

Squamous cell carcinoma

The presence of squamous cell carcinoma of the skin. [from HPO]

MedGen UID:
505376
Concept ID:
CN002585
Finding
10.

Staining (finding)

MedGen UID:
352872
Concept ID:
C1704680
Finding
11.

Squamous cell carcinoma of the head and neck

Squamous cell carcinoma is a cancer that arises from particular cells called squamous cells. Squamous cells are found in the outer layer of skin and in the mucous membranes, which are the moist tissues that line body cavities such as the airways and intestines. Head and neck squamous cell carcinoma (HNSCC) develops in the mucous membranes of the mouth, nose, and throat.HNSCC is classified by its location: it can occur in the mouth (oral cavity), the middle part of the throat near the mouth (oropharynx), the space behind the nose (nasal cavity and paranasal sinuses), the upper part of the throat near the nasal cavity (nasopharynx), the voicebox (larynx), or the lower part of the throat near the larynx (hypopharynx). Depending on the location, the cancer can cause abnormal patches or open sores (ulcers) in the mouth and throat, unusual bleeding or pain in the mouth, sinus congestion that does not clear, sore throat, earache, pain when swallowing or difficulty swallowing, a hoarse voice, difficulty breathing, or enlarged lymph nodes.HNSCC can spread (metastasize) to other parts of the body, such as the lymph nodes or lungs. If it spreads, the cancer has a worse prognosis and can be fatal. About half of affected individuals survive more than five years after diagnosis.
[from GHR]

MedGen UID:
257911
Concept ID:
C1168401
Neoplastic Process
12.

Proliferation

MedGen UID:
137720
Concept ID:
C0334094
Pathologic Function
13.

Examined for

Having been subjected to inspection or evaluation. [from NCI]

MedGen UID:
83047
Concept ID:
C0332128
Finding
14.

Estrogen Antagonists

substances or agents which suppress, prevent or oppose the action of estrogen. [from CRISP]

MedGen UID:
5037
Concept ID:
C0014930
Pharmacologic Substance
15.

Squamous cell carcinoma

The presence of squamous cell carcinoma of the skin. [from HPO]

MedGen UID:
2874
Concept ID:
C0007137
Neoplastic Process
16.

Aerodiol

MedGen UID:
365356
Concept ID:
C1951509
Hormone; Organic Chemical; Pharmacologic Substance
17.

Oral leukoplakia

A thickened white patch on the oral mucosa that cannot be rubbed off. [from HPO]

MedGen UID:
316451
Concept ID:
C1704317
Anatomical Abnormality
18.

Epithelial Neoplasm

A benign or malignant neoplasm that arises from and is composed of epithelial cells. This category include adenomas, papillomas, and carcinomas. [from NCI]

MedGen UID:
277963
Concept ID:
C1368683
Neoplastic Process
19.

Vivelle

MedGen UID:
196344
Concept ID:
C0724374
Hormone; Organic Chemical; Pharmacologic Substance
20.

Pathological Conditions, Anatomical

An abnormal structural condition of the human body, usually macroscopic, that is common to a variety of different diseases. [from MeSH]

MedGen UID:
155708
Concept ID:
C0752135
Pathologic Function
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