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1.

Lymphoma

Lymphoma is a cancer of a part of the immune system called the lymph system. There are many types of lymphoma. One type is Hodgkin disease. The rest are called non-Hodgkin lymphomas. Non-Hodgkin lymphomas begin when a type of white blood cell, called a T cell or B cell, becomes abnormal. The cell divides again and again, making more and more abnormal cells. These abnormal cells can spread to almost any other part of the body. Most of the time, doctors don't know why a person gets non-Hodgkin lymphoma. You are at increased risk if you have a weakened immune system or have certain types of infections. Non-Hodgkin lymphoma can cause many symptoms, such as . -Swollen, painless lymph nodes in the neck, armpits or groin. -Unexplained weight loss . -Fever . -Soaking night sweats . -Coughing, trouble breathing or chest pain . -Weakness and tiredness that don't go away . -Pain, swelling or a feeling of fullness in the abdomen . Your doctor will diagnose lymphoma with a physical exam, blood tests, a chest x-ray, and a biopsy. Treatments include chemotherapy, radiation therapy, targeted therapy, biological therapy, or therapy to remove proteins from the blood. Targeted therapy uses substances that attack cancer cells without harming normal cells. Biologic therapy boosts your body's own ability to fight cancer. If you don't have symptoms, you may not need treatment right away. This is called watchful waiting. NIH: National Cancer Institute.  [from MedlinePlus]

MedGen UID:
44223
Concept ID:
C0024299
Neoplastic Process
2.

Diffuse Mixed Cell Lymphoma

An antiquated term referring to non-Hodgkin lymphomas with a mixed cellular composition. This term applies to both B- and T- cell non-Hodgkin lymphomas. [from NCI]

MedGen UID:
42542
Concept ID:
C0079757
Neoplastic Process
3.

Lymphoma, Large-Cell, Diffuse

MedGen UID:
880992
Concept ID:
CN236674
Disease or Syndrome
4.

Lymphoma

A cancer originating in lymphocytes and presenting as a solid tumor of lymhpoid cells. [from HPO]

MedGen UID:
505322
Concept ID:
CN002422
Finding
5.

Pathogenesis

specific processes that generate the ability of an organism to cause disease [from CHV]

MedGen UID:
195936
Concept ID:
C0699748
Pathologic Function
6.

Diffuse

A spatial pattern that is spread out, i.e., not localized. [from HPO]

MedGen UID:
61387
Concept ID:
C0205219
Spatial Concept
7.

Mutagenesis Process

Process of generating a genetic MUTATION. It may occur spontaneously or be induced by MUTAGENS. [from MeSH]

MedGen UID:
86969
Concept ID:
C0079866
Molecular Function
8.

Neoplasm

A malignant tumor at the original site of growth. [from NCI]

MedGen UID:
227011
Concept ID:
C1306459
Neoplastic Process
9.

Malignant lymphoma, large B-cell, diffuse

Malignant lymphoma composed of large B lymphoid cells whose nuclear size can exceed normal macrophage nuclei, or more than twice the size of a normal lymphocyte. The pattern is predominantly diffuse. Most of these lymphomas represent the malignant counterpart of B-lymphocytes at midstage in the process of differentiation. [from MeSH]

MedGen UID:
86954
Concept ID:
C0079744
Neoplastic Process
10.

B-cell lymphoma

A type of lymphoma that originates in B-cells. [from HPO]

MedGen UID:
86953
Concept ID:
C0079731
Neoplastic Process
11.

Central

Applies to an abnormality that is located close to the median plane or midline of the body or of the referenced structure. [from HPO]

MedGen UID:
59958
Concept ID:
C0205099
Spatial Concept
12.

Lymphosarcoma

An obsolete term for a malignant tumor of lymphatic tissue. [from NCI_NCI-GLOSS]

MedGen UID:
811370
Concept ID:
C3714542
Neoplastic Process
13.

Lymphatism

MedGen UID:
141817
Concept ID:
C0524631
Disease or Syndrome
14.

Diffuse non-Hodgkin lymphoma, undifferentiated

MedGen UID:
44226
Concept ID:
C0024306
Neoplastic Process
15.

Mixed Cell Lymphoma

An antiquated term that refers to a lymphoma composed of a mixture of small and large lymphocytes. [from NCI]

MedGen UID:
44225
Concept ID:
C0024304
Neoplastic Process
16.

Low Grade Lymphoma

An antiquated term that refers to a non-Hodgkin lymphoma with low grade histologic features. [from NCI]

MedGen UID:
42540
Concept ID:
C0079747
Neoplastic Process
17.

Intermediate Grade Lymphoma

An antiquated term that refers to a non-Hodgkin lymphoma with intermediate grade histologic features. [from NCI]

MedGen UID:
38239
Concept ID:
C0079741
Neoplastic Process
18.

High Grade Lymphoma

A type of lymphoma that grows and spreads quickly and has severe symptoms. Also called aggressive lymphoma and intermediate-grade lymphoma. [from NCI_NCI-GLOSS]

MedGen UID:
38238
Concept ID:
C0079740
Neoplastic Process
19.

Neoplasms by Histologic Type

A collective term for the various histological types of NEOPLASMS. It is more likely to be used by searchers than by indexers and catalogers. [from MeSH]

MedGen UID:
10295
Concept ID:
C0027652
Neoplastic Process
20.

Abnormality of the lymphatic system

The lymphatic system is a network of tissues and organs. It is made up of. -Lymph - a fluid that contains white blood cells that defend against germs. -Lymph vessels - vessels that carry lymph throughout your body. They are different from blood vessels. -Lymph nodes - glands found throughout the lymph vessels. Along with your spleen, these nodes are where white blood cells fight infection. Your bone marrow and thymus produce the cells in lymph. They are part of the system, too. The lymphatic system clears away infection and keeps your body fluids in balance. If it's not working properly, fluid builds in your tissues and causes swelling, called lymphedema. Other lymphatic system problems can include infections, blockage, and cancer.  [from MedlinePlus]

MedGen UID:
9829
Concept ID:
C0024228
Disease or Syndrome
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