Format
Items per page

Send to:

Choose Destination

Links from PubMed

Items: 1 to 20 of 29

1.

Malignant Breast Neoplasm

A primary or metastatic malignant neoplasm involving the breast. The vast majority of cases are carcinomas arising from the breast parenchyma or the nipple. Malignant breast neoplasms occur more frequently in females than in males. [from NCI]

MedGen UID:
651
Concept ID:
C0006142
Neoplastic Process
2.

breast cancer

MedGen UID:
880206
Concept ID:
CN235590
Finding
3.

Neoplasm of the breast

Breast cancer is a disease in which certain cells in the breast become abnormal and multiply uncontrollably to form a tumor. Although breast cancer is much more common in women, this form of cancer can also develop in men. In both women and men, the most common form of breast cancer begins in cells lining the milk ducts (ductal cancer). In women, cancer can also develop in the glands that produce milk (lobular cancer). Most men have little or no lobular tissue, so lobular cancer in men is very rare.In its early stages, breast cancer usually does not cause pain and may exhibit no noticeable symptoms. As the cancer progresses, signs and symptoms can include a lump or thickening in or near the breast; a change in the size or shape of the breast; nipple discharge, tenderness, or retraction (turning inward); and skin irritation, dimpling, or scaliness. However, these changes can occur as part of many different conditions. Having one or more of these symptoms does not mean that a person definitely has breast cancer.In some cases, cancerous tumors can invade surrounding tissue and spread to other parts of the body. If breast cancer spreads, cancerous cells most often appear in the bones, liver, lungs, or brain. Tumors that begin at one site and then spread to other areas of the body are called metastatic cancers.A small percentage of all breast cancers cluster in families. These cancers are described as hereditary and are associated with inherited gene mutations. Hereditary breast cancers tend to develop earlier in life than noninherited (sporadic) cases, and new (primary) tumors are more likely to develop in both breasts. [from GTR]

MedGen UID:
264172
Concept ID:
C1458155
Neoplastic Process
4.

Breast carcinoma

A carcinoma arising from the breast, most commonly the terminal ductal-lobular unit. It is the most common malignant tumor in females. Risk factors include country of birth, family history, menstrual and reproductive history, fibrocystic disease and epithelial hyperplasia, exogenous estrogens, contraceptive agents, and ionizing radiation. The vast majority of breast carcinomas are adenocarcinomas (ductal or lobular). Breast carcinoma spreads by direct invasion, by the lymphatic route, and by the blood vessel route. The most common site of lymph node involvement is the axilla. [from NCI]

MedGen UID:
146260
Concept ID:
C0678222
Neoplastic Process
5.

sesamolin

MedGen UID:
127267
Concept ID:
C0632192
Pharmacologic Substance
6.

sesamol

MedGen UID:
22935
Concept ID:
C0074406
Organic Chemical; Pharmacologic Substance
7.

sesamin

MedGen UID:
22934
Concept ID:
C0074405
Organic Chemical; Pharmacologic Substance
8.

Progesterone

A synthetic form of the endogenous hormone progesterone. Progesterone binds to the progesterone receptor, resulting in dissociation of heat shock proteins, receptor phosphorylation, and transcription activation through direct or indirect interaction with transcription factors. This agent exerts inhibitory effects on estrogens by decreasing the number of estrogen receptors and increasing its metabolism to inactive metabolites. Progesterone induces secretory changes in the endometrium, decreases uterine contractility during pregnancy, and maintains pregnancy. (NCI04) [from NCI]

MedGen UID:
18661
Concept ID:
C0033308
Hormone; Organic Chemical; Pharmacologic Substance
9.

Estradiol

A steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Typically esterified, estradiol derivatives are formulated for oral or parenteral administration. As the primary, most potent estrogen hormone produced by the ovaries, estradiol binds to and activates specific nuclear receptors. Estradiol exhibits mild anabolic and metabolic properties, and increases blood coagulability. [from NCI]

MedGen UID:
4551
Concept ID:
C0014912
Hormone; Organic Chemical; Pharmacologic Substance
10.

Indicated

MedGen UID:
731837
Concept ID:
C1444656
Finding
11.

Very low

MedGen UID:
617805
Concept ID:
C0442811
Finding
12.

Estrogenic preparation

A class of natural or synthetic hormones that binds to a cytoplasmic receptor and initiates translocation of the hormone-receptor complex to the nucleus of target cells of tissues rich in estrogen receptors, including the endometrium, myometrium, oviduct, vagina, fallopian tube, cervix, brain, liver, placenta, ovarian cells, Leydigs cells, kidney, prostate, pancreas, heart, and skin. (NCI) [from NCI]

MedGen UID:
8701
Concept ID:
C0014939
Hormone; Organic Chemical; Pharmacologic Substance
13.

Plant Preparations

Material prepared from plants. [from MeSH]

MedGen UID:
183699
Concept ID:
C0949854
Pharmacologic Substance
14.

Estrogen Receptor Modulator

Substances that possess antiestrogenic actions but can also produce estrogenic effects as well. They act as complete or partial agonist or as antagonist. They can be either steroidal or nonsteroidal in structure. [from MeSH]

MedGen UID:
156034
Concept ID:
C0752229
Pharmacologic Substance
15.

Skin and Connective Tissue Diseases

A collective term for diseases of the skin and its appendages and of connective tissue. [from MeSH]

MedGen UID:
59786
Concept ID:
C0175166
Disease or Syndrome
16.

Non-steroidal estrogen preparation

Estrogens that are not steroids, but have a structural configuration resembling steroids and may mimic steroidal estrogen effect or bind to estrogen receptors. [from NCI]

MedGen UID:
41879
Concept ID:
C0014940
Hormone; Organic Chemical; Pharmacologic Substance
17.

Phytoestrogen

Compounds from plant sources with estrogen-like activities [from NCI]

MedGen UID:
33114
Concept ID:
C0071011
Hormone; Organic Chemical; Pharmacologic Substance
18.

dermopathy

An abnormality of the skin. [from HPO]

MedGen UID:
20777
Concept ID:
C0037274
Disease or Syndrome
19.

General drug type

A drug product that contains one or more active and/or inactive ingredients; it is intended to treat, prevent or alleviate the symptoms of disease. This term does not refer to the individual ingredients that make up the product. [from NCI]

MedGen UID:
8496
Concept ID:
C0013227
Pharmacologic Substance
20.

Hormones, Hormone Substitutes, and Hormone Antagonists

A collective grouping for both naturally occurring and synthetic hormones, substitutes, and antagonists. [from MeSH]

MedGen UID:
6887
Concept ID:
C0019934
Pharmacologic Substance
Format
Items per page

Send to:

Choose Destination

Supplemental Content

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center