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Items: 1 to 20 of 26

1.

Memory impairment

An impairment of memory as manifested by a reduced ability to remember things such as dates and names, and increased forgetfulness. [from HPO]

MedGen UID:
68579
Concept ID:
C0233794
Mental or Behavioral Dysfunction
2.

Impairment

MedGen UID:
151925
Concept ID:
C0684336
Pathologic Function
3.

Water

A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) [from MeSH]

MedGen UID:
22697
Concept ID:
C0043047
Inorganic Chemical; Pharmacologic Substance
4.

Picrotoxin

A noncompetitive antagonist at GABA-A receptors and thus a convulsant. Picrotoxin blocks the GAMMA-AMINOBUTYRIC ACID-activated chloride ionophore. Although it is most often used as a research tool, it has been used as a CNS stimulant and an antidote in poisoning by CNS depressants, especially the barbiturates. [from MeSH]

MedGen UID:
18473
Concept ID:
C0031890
Hazardous or Poisonous Substance; Organic Chemical; Pharmacologic Substance
5.

Pentobarbital

A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236) [from MeSH]

MedGen UID:
18362
Concept ID:
C0030883
Organic Chemical; Pharmacologic Substance
6.

Tauopathy

Neurodegenerative disorders involving deposition of abnormal tau protein isoforms (TAU PROTEINS) in neurons and glial cells in the brain. Pathological aggregations of tau proteins are associated with mutation of the tau gene on chromosome 17 in patients with ALZHEIMER DISEASE; DEMENTIA; PARKINSONIAN DISORDERS; progressive supranuclear palsy (SUPRANUCLEAR PALSY, PROGRESSIVE); and corticobasal degeneration. [from MeSH]

MedGen UID:
181880
Concept ID:
C0949664
Disease or Syndrome
7.

Risk factor

An aspect of personal behavior or lifestyle, environmental exposure, inborn or inherited characteristic, which, on the basis of epidemiological evidence, is known to be associated with a health-related condition considered important to prevent. [from MeSH]

MedGen UID:
48477
Concept ID:
C0035648
Finding
8.

Neurodegeneration

Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways. [from MeSH]

MedGen UID:
17999
Concept ID:
C0027746
Cell or Molecular Dysfunction
9.

Alzheimer disease

Alzheimer disease (AD) is characterized by dementia that typically begins with subtle and poorly recognized failure of memory and slowly becomes more severe and, eventually, incapacitating. Other common findings include confusion, poor judgment, language disturbance, agitation, withdrawal, and hallucinations. Occasionally, seizures, Parkinsonian features, increased muscle tone, myoclonus, incontinence, and mutism occur. Death usually results from general inanition, malnutrition, and pneumonia. The typical clinical duration of the disease is eight to ten years, with a range from one to 25 years. Approximately 25% of all AD is familial (i.e., =2 persons in a family have AD) of which approximately 95% is late onset (age >60-65 years) and 5% is early onset (age <65 years). [from GTR]

MedGen UID:
1853
Concept ID:
C0002395
Disease or Syndrome
10.

Aminobutyrates

Derivatives of BUTYRIC ACID that contain one or more amino groups attached to the aliphatic structure. Included under this heading are a broad variety of acid forms, salts, esters, and amides that include the aminobutryrate structure. [from MeSH]

MedGen UID:
473507
Concept ID:
C1979618
Organic Chemical; Pharmacologic Substance
11.

Diabutal

MedGen UID:
196194
Concept ID:
C0702209
Organic Chemical; Pharmacologic Substance
12.

Etaminal

MedGen UID:
184909
Concept ID:
C0947688
Organic Chemical; Pharmacologic Substance
13.

Gammalon

MedGen UID:
147623
Concept ID:
C0733457
Amino Acid, Peptide, or Protein; Biologically Active Substance; Pharmacologic Substance
14.

Nembutal

MedGen UID:
147319
Concept ID:
C0702208
Organic Chemical; Pharmacologic Substance
15.

Neurobehavioral Manifestations

Signs and symptoms of higher cortical dysfunction caused by organic conditions. These include certain behavioral alterations and impairments of skills involved in the acquisition, processing, and utilization of knowledge or information. [from MeSH]

MedGen UID:
105653
Concept ID:
C0525041
Sign or Symptom
16.

Mebumal

MedGen UID:
79419
Concept ID:
C0282293
Organic Chemical; Pharmacologic Substance
17.

barbiturate

MedGen UID:
67405
Concept ID:
C0220791
Organic Chemical; Pharmacologic Substance
18.

Sagatal

MedGen UID:
48531
Concept ID:
C0036050
Organic Chemical; Pharmacologic Substance
19.

Clinical finding

Clinical manifestations that can be either objective when observed by a physician, or subjective when perceived by the patient. [from MeSH]

MedGen UID:
19974
Concept ID:
C0037088
Sign or Symptom
20.

Neurologic Manifestations

Clinical signs and symptoms caused by nervous system injury or dysfunction. [from MeSH]

MedGen UID:
18017
Concept ID:
C0027854
Finding
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