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Items: 10

1.

Renal insufficiency

A reduction in the level of performance of the kidneys in areas of function comprising the concentration of urine, removal of wastes, the maintenance of electrolyte balance, homeostasis of blood pressure, and calcium metabolism. [from HPO]

MedGen UID:
332529
Concept ID:
C1565489
Disease or Syndrome
2.

Polyarteritis nodosa

Childhood-onset polyarteritis nodosa is an autosomal recessive systemic vascular inflammatory disorder characterized mainly by involvement of the skin, nervous system, kidney, and gastrointestinal tract. There is considerable variability in the severity and age at onset, although most patients have onset of symptoms in the first decade. Features include recurrent ischemic stroke affecting the small vessels of the brain and resulting in neurologic dysfunction, recurrent fever, elevated acute-phase proteins, myalgias, and livedo racemosa or reticularis with an inflammatory vasculitis on biopsy. Some patients develop hypertension, aneurysms, or ischemic necrosis of the digits (summary by Zhou et al., 2014 and Navon Elkan et al., 2014). Some patients present with clinical immunodeficiency (van Eyck et al., 2014). [from OMIM]

MedGen UID:
14681
Concept ID:
C0031036
Disease or Syndrome
3.

progressive

MedGen UID:
851455
Concept ID:
CN232553
Finding
4.

Polyarteritis

MedGen UID:
539001
Concept ID:
C0264992
Disease or Syndrome
5.

Renal insufficiency

A reduction in the level of performance of the kidneys in areas of function comprising the concentration of urine, removal of wastes, the maintenance of electrolyte balance, homeostasis of blood pressure, and calcium metabolism. [from HPO]

MedGen UID:
326535
Concept ID:
C1839604
Finding
6.

Rapidly progressive

MedGen UID:
325078
Concept ID:
C1838681
Finding
7.

Chronic kidney disease

Functional anomaly of the kidney persisting for at least three months. [from HPO]

MedGen UID:
196667
Concept ID:
C0748318
Finding
8.

Progressive

Advancing in extent or severity. [from NCI]

MedGen UID:
64400
Concept ID:
C0205329
Functional Concept
9.

Renal failure

Healthy kidneys clean your blood by removing excess fluid, minerals, and wastes. They also make hormones that keep your bones strong and your blood healthy. But if the kidneys are damaged, they don't work properly. Harmful wastes can build up in your body. Your blood pressure may rise. Your body may retain excess fluid and not make enough red blood cells. This is called kidney failure. If your kidneys fail, you need treatment to replace the work they normally do. The treatment options are dialysis or a kidney transplant. Each treatment has benefits and drawbacks. No matter which treatment you choose, you'll need to make some changes in your life, including how you eat and plan your activities. But with the help of healthcare providers, family, and friends, most people with kidney failure can lead full and active lives. NIH: National Institute of Diabetes and Digestive and Kidney Diseases.  [from MedlinePlus]

MedGen UID:
11177
Concept ID:
C0035078
Disease or Syndrome
10.

Subsequent Relapse

The reemergence of a disorder as diagnosed by clinical and/or laboratory evidence following two or more documented periods of remission. [from NCI]

MedGen UID:
886700
Concept ID:
C4053982
Finding
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