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Items: 10

1.

Decreased pulmonary function

A decrease in ventilation secondary to impaired signals from the central nervous system.(AE) [from NCI_NICHD]

MedGen UID:
68612
Concept ID:
C0235063
Pathologic Function
2.

Pain

Pain is a feeling triggered in the nervous system. Pain may be sharp or dull. It may come and go, or it may be constant. You may feel pain in one area of your body, such as your back, abdomen or chest or you may feel pain all over, such as when your muscles ache from the flu. Pain can be helpful in diagnosing a problem. Without pain, you might seriously hurt yourself without knowing it, or you might not realize you have a medical problem that needs treatment. Once you take care of the problem, pain usually goes away. However, sometimes pain goes on for weeks, months or even years. This is called chronic pain. Sometimes chronic pain is due to an ongoing cause, such as cancer or arthritis. Sometimes the cause is unknown. Fortunately, there are many ways to treat pain. Treatment varies depending on the cause of pain. Pain relievers, acupuncture and sometimes surgery are helpful.  [from MedlinePlus]

MedGen UID:
45282
Concept ID:
C0030193
Sign or Symptom
3.

Depression

MedGen UID:
881016
Concept ID:
CN236657
Disease or Syndrome
4.

Pain

MedGen UID:
880950
Concept ID:
CN236637
Disease or Syndrome
5.

Hypoventilation

A reduction in the amount of air transported into the pulmonary alveoli by breathing, leading to hypercapnia (increase in the partial pressure of carbon dioxide). [from HPO]

MedGen UID:
469022
Concept ID:
C3203358
Pathologic Function
6.

Addictive behavior

A recurrent pattern of behavior that is characeterized by the failure to resist an impulse, drive, or temptation to perform an act that is harmful to the person or to others. The repetitive engagement in these behaviors ultimately interferes with functioning in other domains. [from HPO]

MedGen UID:
88373
Concept ID:
C0085281
Mental or Behavioral Dysfunction
7.

Depression

Depression is a serious medical illness that involves the brain. It's more than just a feeling of being "down in the dumps" or "blue" for a few days. If you are one of the more than 20 million people in the United States who have depression, the feelings do not go away. They persist and interfere with your everyday life. Symptoms can include : -Sadness. -Loss of interest or pleasure in activities you used to enjoy. -Change in weight. -Difficulty sleeping or oversleeping. -Energy loss. -Feelings of worthlessness. -Thoughts of death or suicide. Depression is a disorder of the brain. There are a variety of causes, including genetic, environmental, psychological, and biochemical factors. Depression usually starts between the ages of 15 and 30, and is much more common in women. Women can also get postpartum depression after the birth of a baby. Some people get seasonal affective disorder in the winter. Depression is one part of bipolar disorder. There are effective treatments for depression, including antidepressants and talk therapy. Most people do best by using both. . NIH: National Institute of Mental Health.  [from MedlinePlus]

MedGen UID:
4229
Concept ID:
C0011581
Mental or Behavioral Dysfunction
8.

fentanyl response - Metabolism/PK

MedGen UID:
881078
Concept ID:
CN236592
Sign or Symptom
9.

alfentanil response - Metabolism/PK

MedGen UID:
881023
Concept ID:
CN236463
Sign or Symptom
10.

opioids response - Metabolism/PK

MedGen UID:
880970
Concept ID:
CN236604
Sign or Symptom
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