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Items: 1 to 20 of 26

1.

Shock

A life-threatening condition that requires immediate medical intervention. It is characterized by reduced blood flow that may result in damage of multiple organs. Types of shock include cardiogenic, hemorrhagic, septic, anaphylactic, and traumatic shock. [from NCI]

MedGen UID:
20738
Concept ID:
C0036974
Pathologic Function
2.

Inflammation

A localized protective response resulting from injury or destruction of tissues. Inflammation serves to destroy, dilute, or wall off both the injurious agent and the injured tissue. In the acute phase, inflammation is characterized by the signs of pain, heat, redness, swelling, and loss of function. Histologically, inflammation involves a complex series of events, including dilatation of arterioles, capillaries, and venules, with increased permeability and blood flow; exudation of fluids, including plasma proteins; and leukocyte migration into the site of inflammation. [from NCI]

MedGen UID:
7072
Concept ID:
C0021368
Pathologic Function
3.

Reduced ejection fraction

A diminution of the volumetric fraction of blood pumped out of the ventricle with each cardiac cycle. [from HPO]

MedGen UID:
868398
Concept ID:
C4022792
Finding
4.

Pressure

MedGen UID:
632176
Concept ID:
C0460139
Finding
5.

Left

Being located on the left side of the body. [from HPO]

MedGen UID:
618170
Concept ID:
C0443246
Spatial Concept
6.

Myocardial dysfunction

MedGen UID:
573775
Concept ID:
C0340515
Pathologic Function
7.

Laurin-Sandrow syndrome

A hand or foot with more than five digits that has a recognizable A/P axis of symmetry. The axis can lie within a normally formed or partially duplicated digit resembling a middle finger, index finger, thumb, toe, or hallux. Alternatively, the axis can be in an interdigital space with a flanking pair of digits that resemble a middle finger, index finger, thumb, toe or hallux. The most lateral digits on each side of the hand typically resemble fifth fingers/toes. [from HPO]

MedGen UID:
340697
Concept ID:
C1851100
Disease or Syndrome
8.

Ectatic

The condition of being dilated or stretched. [from NCI]

MedGen UID:
148572
Concept ID:
C0700124
Finding
9.

Acute

Sudden appearance of disease manifestations over a short period of time. [from HPO]

MedGen UID:
61381
Concept ID:
C0205178
Temporal Concept
10.

Septic shock

A state of acute circulatory failure characterized by persistent arterial hypotension despite adequate fluid resuscitation or by tissue hypoperfusion unexplained by other causes.(NICHD) [from NCI]

MedGen UID:
11410
Concept ID:
C0036983
Pathologic Function
11.

Infection

The invasion of an organism's body tissues by disease-causing agents and their multiplication, as well as the reaction by the host to these organisms and/or toxins that the organisms produce. [from NCI]

MedGen UID:
811352
Concept ID:
C3714514
Pathologic Function
12.

Toxic shock syndrome

A rare acute life-threatening systemic bacterial noncontagious illness caused by any of several related staphylococcal exotoxins. It is characterized by high fever, hypotension, rash, multi-organ dysfunction, and cutaneous desquamation during the early convalescent period. The toxins affect the host immune system, causing an exuberant and pathological host inflammatory response. Laboratory findings include leukocytosis, elevated prothrombin time, hypoalbuminemia, hypocalcemia, and pyuria. [from NCI]

MedGen UID:
109414
Concept ID:
C0600327
Disease or Syndrome
13.

Disease due to Gram-negative bacteria

Infections caused by bacteria that show up as pink (negative) when treated by the gram-staining method. [from MeSH]

MedGen UID:
88406
Concept ID:
C0085423
Disease or Syndrome
14.

Sepsis

Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK. [from MeSH]

MedGen UID:
69314
Concept ID:
C0243026
Disease or Syndrome
15.

Systemic inflammatory response syndrome

A generalized state of dysregulated inflammation induced by noninfectious processes. It is characterized by two or more of the following signs and symptoms: fever or hypothermia, increased heart rate, increased respiratory rate, and abnormal white blood cell count.(NICHD) [from NCI]

MedGen UID:
69303
Concept ID:
C0242966
Disease or Syndrome
16.

Sepsis

Systemic disease associated with the presence of pathogenic microorganisms or their toxins in the blood. [from MeSH]

MedGen UID:
48626
Concept ID:
C0036690
Disease or Syndrome
17.

Salmonella infection

Infections with bacteria of the genus SALMONELLA. [from MeSH]

MedGen UID:
48542
Concept ID:
C0036117
Disease or Syndrome
18.

Endotoxic shock

MedGen UID:
19963
Concept ID:
C0036981
Pathologic Function
19.

Pyemia

Septicemia caused by pyogenic microorganisms (e.g., STAPHYLOCOCCUS; BACILLUS), resulting in the formation of secondary foci of SUPPURATION and multiple ABSCESSES. [from MeSH]

MedGen UID:
18779
Concept ID:
C0034189
Pathologic Function
20.

Bacterial infection by site

An acute infectious disorder that is caused by gram positive or gram negative bacteria; representative examples include pneumococcal, streptococcal, salmonella, and meningeal infections. [from NCI]

MedGen UID:
14012
Concept ID:
C0004623
Disease or Syndrome
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