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Items: 15

1.

Fluvoxamine

A 2-aminoethyl oxime ether of aralkylketones, with antidepressant, antiobsessive-compulsive, and anxiolytic properties. Fluvoxamine, chemically unrelated to other selective serotonin reuptake inhibitors, selectively blocks serotonin reuptake by inhibiting the serotonin reuptake pump at the presynaptic neuronal membrane. This increases serotonin levels within the synaptic cleft, prolongs serotonergic transmission and decreased serotonin turnover, thereby leading to antidepressant, anxiolytic and antiobsessive-compulsive effects. Fluvoxamine shows no significant affinity for histaminergic, alpha or beta adrenergic, muscarinic, or dopaminergic receptors in vitro. [from NCI]

MedGen UID:
88359
Concept ID:
C0085228
Organic Chemical; Pharmacologic Substance
2.

Obsessive compulsive disorder

A disorder characterized by the presence of persistent and recurrent irrational thoughts (obsessions), resulting in marked anxiety and repetitive excessive behaviors (compulsions) as a way to try to decrease that anxiety. [from NCI]

MedGen UID:
14445
Concept ID:
C0028768
Mental or Behavioral Dysfunction
3.

Obsessive-compulsive disorder

Obsessive-compulsive disorder (OCD) is characterized by recurring obsessions and/or compulsions and has been estimated to affect nearly 5 million people in the United States (Karno et al., 1988). Evidence for a strong genetic component in OCD comes from twin studies, family genetics studies, and segregation analyses, as reviewed by Alsobrook et al. (2002). Zhang et al. (2002) suggested that hoarding is likely to be an evolutionarily conserved trait that, in times of adversity, was associated with increased survival and reproductive fitness. However, extreme forms of this trait are associated with marked disability and poor response to treatment (Black et al., 1998; Mataix-Cols et al., 1999). [from GTR]

MedGen UID:
320254
Concept ID:
C1834037
4.

Side Effect

The term was used in various ways in the past, to describe unintended effects of medical intervention, usually negative (unfavourable), but also positive (favourable) ones. It is recommended that this term no longer be used and particularly should not be regarded as synonymous with adverse event or adverse reaction. [from NCI]

MedGen UID:
163994
Concept ID:
C0879626
Pathologic Function
5.

Disinhibition

A lack of restraint manifested in several ways, including disregard for social conventions, impulsivity, and poor risk assessment. [from HPO]

MedGen UID:
140859
Concept ID:
C0424296
Mental or Behavioral Dysfunction
6.

Obsessive-compulsive behavior

A series of actions or ritualistic behavior that is difficult to suppress and is performed to relieve or prevent anxiety. [from NCI]

MedGen UID:
109373
Concept ID:
C0600104
Mental or Behavioral Dysfunction
7.

PMS-Fluvoxamine

MedGen UID:
339149
Concept ID:
C1567469
Organic Chemical; Pharmacologic Substance
8.

Fluvoxamin-neuraxpharm

MedGen UID:
339148
Concept ID:
C1567464
Organic Chemical; Pharmacologic Substance
9.

Nu-Fluvoxamine

MedGen UID:
298021
Concept ID:
C1567468
Organic Chemical; Pharmacologic Substance
10.

Novo-Fluvoxamine

MedGen UID:
298020
Concept ID:
C1567467
Organic Chemical; Pharmacologic Substance
11.

Fluvoxamin-ratiopharm

MedGen UID:
298018
Concept ID:
C1567465
Organic Chemical; Pharmacologic Substance
12.

Fluvoxadura

MedGen UID:
298017
Concept ID:
C1567460
Organic Chemical; Pharmacologic Substance
13.

Desiflu

MedGen UID:
291350
Concept ID:
C1567459
Organic Chemical; Pharmacologic Substance
14.

DU-23000

MedGen UID:
152197
Concept ID:
C0700735
Organic Chemical; Pharmacologic Substance
15.

Luvox

MedGen UID:
39420
Concept ID:
C0086307
Organic Chemical; Pharmacologic Substance
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