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Items: 1 to 20 of 28

1.

Insulin resistance

Increased resistance towards insulin, that is, diminished effectiveness of insulin in reducing blood glucose levels. [from HPO]

MedGen UID:
43904
Concept ID:
C0021655
Pathologic Function
2.

Glucagon

A hormone produced by the pancreas that increases the level of glucose (sugar) in the blood. [from NCI]

MedGen UID:
6620
Concept ID:
C0017687
Amino Acid, Peptide, or Protein; Hormone; Neuroreactive Substance or Biogenic Amine; Pharmacologic Substance
3.

Insulin

Insulin (51 aa, ~6 kDa) is encoded by the human INS gene. This protein is involved in the direct regulation of glucose metabolism. [from NCI]

MedGen UID:
5827
Concept ID:
C0021641
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
4.

Insulin resistance

Increased resistance towards insulin, that is, diminished effectiveness of insulin in reducing blood glucose levels. [from HPO]

MedGen UID:
504630
Concept ID:
CN000801
Finding
5.

Fat

The glyceryl esters of a fatty acid, or of a mixture of fatty acids. They are generally odorless, colorless, and tasteless if pure, but they may be flavored according to origin. Fats are insoluble in water, soluble in most organic solvents. They occur in animal and vegetable tissue and are generally obtained by boiling or by extraction under pressure. They are important in the diet (DIETARY FATS) as a source of energy. (Grant & Hackh's Chemical Dictionary, 5th ed) [from MeSH]

MedGen UID:
5132
Concept ID:
C0015677
Lipid; Organic Chemical; Pharmacologic Substance
6.

Glucose

A hexose with an aldehyde group; in which each of the 5 remaining carbons other than the aldehyde group has one hydroxyl group in the R,S,R, and R configuration counting from the first hydroxyl containing carbon next to the aldehyde in the straight chain (Fisher) projection; otherwise all carbons have exclusively hydrogens. Occurs mostly as pyran (6-membered oxygen containing ring or oxane) and rarely as furan (5-membered oxygen containing ring) or straight chain. When glucose forms a ring an additional ""anomeric"" asymmetric carbon is created which is denoted as ""alpha"" or ""beta"". For isomers see http://en.wikipedia.org/wiki/Glucose. [from NCI]

MedGen UID:
42238
Concept ID:
C0017725
Biologically Active Substance; Carbohydrate; Organic Chemical; Pharmacologic Substance
7.

Deoxyglucose

2-Deoxy-D-arabino-hexose. An antimetabolite of glucose with antiviral activity. [from MeSH]

MedGen UID:
41492
Concept ID:
C0011501
Carbohydrate; Organic Chemical; Pharmacologic Substance
8.

Metabolic induction

The conversion of an exogenous substance by a biological system resulting in the production on an active metabolite. [from MeSH]

MedGen UID:
7561
Concept ID:
C0025513
Molecular Function
9.

Male gender

A person who belongs to the sex that normally produces sperm. The term is used to indicate biological sex distinctions, cultural gender role distinctions, or both. (NCI) [from NCI]

MedGen UID:
7446
Concept ID:
C0024554
Finding; Organism Attribute
10.

Independent

MedGen UID:
721426
Concept ID:
C1299583
Finding
11.

Visual Suppression

MedGen UID:
526147
Concept ID:
C0221103
Pathologic Function
12.

Ability to balance

The maintenance of a stable, upright body position. [from NCI]

MedGen UID:
154340
Concept ID:
C0560184
Finding
13.

Mass of body structure

In medicine, a lump in the body. It may be caused by the abnormal growth of cells, a cyst, hormonal changes, or an immune reaction. A mass may be benign (not cancer) or malignant (cancer). [from NCI]

MedGen UID:
108287
Concept ID:
C0577559
Finding
14.

Fish-eye disease

Fish-eye disease, also called partial LCAT deficiency, is a disorder that causes the clear front surface of the eyes (the corneas) to gradually become cloudy. The cloudiness, which generally first appears in adolescence or early adulthood, consists of small grayish dots of cholesterol (opacities) distributed across the corneas. Cholesterol is a waxy, fat-like substance that is produced in the body and obtained from foods that come from animals; it aids in many functions of the body but can become harmful in excessive amounts. As fish-eye disease progresses, the corneal cloudiness worsens and can lead to severely impaired vision. [from GHR]

MedGen UID:
83354
Concept ID:
C0342895
Disease or Syndrome
15.

Insulins

Peptide hormones that cause an increase in the absorption of GLUCOSE by cells within organs such as LIVER, MUSCLE and ADIPOSE TISSUE. During normal metabolism insulins are produced by the PANCREATIC BETA CELLS in response to increased GLUCOSE. Natural and chemically-modified forms of insulin are also used in the treatment of GLUCOSE METABOLISM DISORDERS such as DIABETES MELLITUS. [from MeSH]

MedGen UID:
760846
Concept ID:
C3537244
Pharmacologic Substance
16.

Insulin [EPC]

MedGen UID:
453109
Concept ID:
C1579433
Pharmacologic Substance
17.

Disorder of glucose metabolism

Pathological conditions in which the BLOOD GLUCOSE cannot be maintained within the normal range, such as in HYPOGLYCEMIA and HYPERGLYCEMIA. Etiology of these disorders varies. Plasma glucose concentration is critical to survival for it is the predominant fuel for the CENTRAL NERVOUS SYSTEM. [from MeSH]

MedGen UID:
226229
Concept ID:
C1257958
Disease or Syndrome
18.

Distribution of body fat

Deposits of ADIPOSE TISSUE throughout the body. The pattern of fat deposits in the body regions is an indicator of health status. Excess ABDOMINAL FAT increases health risks more than excess fat around the hips or thighs, therefore, WAIST-HIP RATIO is often used to determine health risks. [from MeSH]

MedGen UID:
98411
Concept ID:
C0424621
Finding
19.

Sugar

A white crystalline carbohydrate, typically sucrose, used as a sweetener and preservative. [from NCI]

MedGen UID:
69157
Concept ID:
C0242209
Carbohydrate; Organic Chemical; Pharmacologic Substance
20.

Nutritional and Metabolic Diseases

A collective term for nutritional disorders resulting from poor absorption or nutritional imbalance, and metabolic disorders resulting from defects in biosynthesis (ANABOLISM) or breakdown (CATABOLISM) of endogenous substances. [from MeSH]

MedGen UID:
45164
Concept ID:
C0028715
Disease or Syndrome
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