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Items: 1 to 20 of 41

1.

cacalol

MedGen UID:
290724
Concept ID:
C1566403
Organic Chemical; Pharmacologic Substance
2.

Malignant Breast Neoplasm

Breast cancer affects one in eight women during their lives. No one knows why some women get breast cancer, but there are many risk factors. Risks that you cannot change include. -Age - the risk rises as you get older. -Genes - two genes, BRCA1 and BRCA2, greatly increase the risk. Women who have family members with breast or ovarian cancer may wish to be tested for the genes. -Personal factors - beginning periods before age 12 or going through menopause after age 55. Other risks include obesity, using hormone replacement therapy (also called menopausal hormone therapy), taking birth control pills, drinking alcohol, not having children or having your first child after age 35, and having dense breasts. Symptoms of breast cancer may include a lump in the breast, a change in size or shape of the breast, and discharge from a nipple. Breast self-exams and mammography can help find breast cancer early, when it is most treatable. One possible treatment is surgery. It could be a lumpectomy or a mastectomy. Other treatments include radiation therapy, chemotherapy, hormone therapy, and targeted therapy. Targeted therapy uses substances that attack cancer cells without harming normal cells. Men can have breast cancer, too, but it is rare. NIH: National Cancer Institute.  [from MedlinePlus]

MedGen UID:
651
Concept ID:
C0006142
Neoplastic Process
3.

breast cancer

MedGen UID:
880206
Concept ID:
CN235590
Finding
4.

Neoplasm of the breast

Breast cancer is a disease in which certain cells in the breast become abnormal and multiply uncontrollably to form a tumor. Although breast cancer is much more common in women, this form of cancer can also develop in men. In both women and men, the most common form of breast cancer begins in cells lining the milk ducts (ductal cancer). In women, cancer can also develop in the glands that produce milk (lobular cancer). Most men have little or no lobular tissue, so lobular cancer in men is very rare.In its early stages, breast cancer usually does not cause pain and may exhibit no noticeable symptoms. As the cancer progresses, signs and symptoms can include a lump or thickening in or near the breast; a change in the size or shape of the breast; nipple discharge, tenderness, or retraction (turning inward); and skin irritation, dimpling, or scaliness. However, these changes can occur as part of many different conditions. Having one or more of these symptoms does not mean that a person definitely has breast cancer.In some cases, cancerous tumors can invade surrounding tissue and spread to other parts of the body. If breast cancer spreads, cancerous cells most often appear in the bones, liver, lungs, or brain. Tumors that begin at one site and then spread to other areas of the body are called metastatic cancers.A small percentage of all breast cancers cluster in families. These cancers are described as hereditary and are associated with inherited gene mutations. Hereditary breast cancers tend to develop earlier in life than noninherited (sporadic) cases, and new (primary) tumors are more likely to develop in both breasts.
[from GHR]

MedGen UID:
264172
Concept ID:
C1458155
Neoplastic Process
5.

Breast carcinoma

The presence of a carcinoma of the breast. [from HPO]

MedGen UID:
146260
Concept ID:
C0678222
Neoplastic Process
6.

Signal Transduction Pathways

An elaboration of the known or inferred interactions involved in a signal transduction pathway. [from NCI]

MedGen UID:
39530
Concept ID:
C0086982
Molecular Function
7.

Fetal alcohol syndrome

Alcohol can harm your baby at any stage during a pregnancy. That includes the earliest stages before you even know you are pregnant. Drinking alcohol can cause a group of conditions called fetal alcohol spectrum disorders (FASDs). Effects can include physical and behavioral problems such as trouble with. -Learning and remembering. -Understanding and following directions. -Controlling emotions. -Communicating and socializing. -Daily life skills, such as feeding and bathing. Fetal alcohol syndrome is the most serious type of FASD. People with fetal alcohol syndrome have facial abnormalities, including wide-set and narrow eyes, growth problems and nervous system abnormalities. FASDs last a lifetime. There is no cure for FASDs. Treatments can help. These include medicines to help with some symptoms and behavior therapy. No one treatment is right for every child. Centers for Disease Control and Prevention.  [from MedlinePlus]

MedGen UID:
8820
Concept ID:
C0015923
Disease or Syndrome
8.

Taxol

brand name of Paclitaxel an anti-cancer drug [from CHV]

MedGen UID:
151846
Concept ID:
C0678133
Organic Chemical; Pharmacologic Substance
9.

Cyclophosphamide

A synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities. In the liver, cyclophosphamide is converted to the active metabolites aldophosphamide and phosphoramide mustard, which bind to DNA, thereby inhibiting DNA replication and initiating cell death. [from NCI]

MedGen UID:
4107
Concept ID:
C0010583
Organic Chemical; Pharmacologic Substance
10.

Free Radical Scavenging

Free Radical Scavenging involves interference with, or restraint of, production, by ready combination with, chemically unstable, short half-life and highly reactive molecules carrying at least one unpaired or 'free' electron in the outermost electron shell. Appropriating electron(s) from a nearby molecule and damaging that molecule by altering the electron number in its outermost electron shell, Free Radicals produce tissue damage. [from NCI]

MedGen UID:
760808
Concept ID:
C3537124
Molecular Function
11.

Chemotherapeutic agent

MedGen UID:
675809
Concept ID:
C0729502
Pharmacologic Substance
12.

Proliferation

MedGen UID:
137720
Concept ID:
C0334094
Pathologic Function
13.

Cytophosphan

MedGen UID:
501178
Concept ID:
C3495431
Organic Chemical; Pharmacologic Substance
14.

Praxel

MedGen UID:
276699
Concept ID:
C1518839
Organic Chemical; Pharmacologic Substance
15.

Anzatax

MedGen UID:
275318
Concept ID:
C1518836
Organic Chemical; Pharmacologic Substance
16.

NSC-26271

MedGen UID:
196095
Concept ID:
C0701106
Organic Chemical; Pharmacologic Substance
17.

Procytox

MedGen UID:
195870
Concept ID:
C0699322
Organic Chemical; Pharmacologic Substance
18.

Endoxan

MedGen UID:
195869
Concept ID:
C0699320
Organic Chemical; Pharmacologic Substance
19.

Onxol

MedGen UID:
181717
Concept ID:
C0939420
Organic Chemical; Pharmacologic Substance
20.

B-518

MedGen UID:
148718
Concept ID:
C0701107
Organic Chemical; Pharmacologic Substance
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