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Items: 1 to 20 of 46

1.

Shock

Shock happens when not enough blood and oxygen can get to your organs and tissues. It causes very low blood pressure and may be life threatening. It often happens along with a serious injury. There are several kinds of shock. Hypovolemic shock happens when you lose a lot of blood or fluids. Causes include internal or external bleeding, dehydration, burns, and severe vomiting and/or diarrhea. Septic shock is caused by infections in the bloodstream. A severe allergic reaction can cause anaphylactic shock. An insect bite or sting might cause it. Cardiogenic shock happens when the heart cannot pump blood effectively. This may happen after a heart attack. Neurogenic shock is caused by damage to the nervous system. Symptoms of shock include. -Confusion or lack of alertness. -Loss of consciousness. -Sudden and ongoing rapid heartbeat. -Sweating. -Pale skin. -A weak pulse. -Rapid breathing. -Decreased or no urine output. -Cool hands and feet. Shock is a life-threatening medical emergency and it is important to get help right away. Treatment of shock depends on the cause. NIH: National Heart, Lung, and Blood Institute.  [from MedlinePlus]

MedGen UID:
20738
Concept ID:
C0036974
Pathologic Function
2.

Nephroblastoma

Wilms tumor is a rare type of kidney cancer. It causes a tumor on one or both kidneys. It usually affects children, but can happen in adults. Having certain genetic conditions or birth defects can increase the risk of getting it. Children that are at risk should be screened for Wilms tumor every three months until they turn eight. Symptoms include a lump in the abdomen, blood in the urine, and a fever for no reason. Tests that examine the kidney and blood are used to find the tumor. Doctors usually diagnose and remove the tumor in surgery. Other treatments include chemotherapy and radiation and biologic therapies. Biologic therapy boosts your body's own ability to fight cancer. NIH: National Cancer Institute.  [from MedlinePlus]

MedGen UID:
10221
Concept ID:
C0027708
Neoplastic Process
3.

Wilms Tumor

MedGen UID:
893580
Concept ID:
CN239467
Disease or Syndrome
4.

Nephroblastoma

The presence of a nephroblastoma, which is a neoplasm of the kidney that primarily affects children. [from HPO]

MedGen UID:
505324
Concept ID:
CN002424
Finding
5.

Wilms tumor 1

Aniridia is characterized by complete or partial iris hypoplasia usually (but not always) with associated foveal hypoplasia resulting in reduced visual acuity and nystagmus presenting in early infancy. Frequently associated ocular abnormalities (often of later onset) include cataract, glaucoma, and corneal opacification and vascularization. Aniridia may occur either as an isolated ocular abnormality without systemic involvement, caused by mutation of PAX6 or deletion of a regulatory region controlling its expression, or as part of the Wilms tumor-aniridia-genital anomalies-retardation (WAGR) syndrome, with a deletion of 11p13 involving the PAX6 (aniridia) locus and the adjacent WT1 (Wilms tumor) locus. Individuals with deletion of PAX6 and WT1 are at up to a 50% risk of developing Wilms tumor. [from GeneReviews]

MedGen UID:
447509
Concept ID:
CN033288
Disease or Syndrome
6.

Neoplasm

A malignant tumor at the original site of growth. [from NCI]

MedGen UID:
227011
Concept ID:
C1306459
Neoplastic Process
7.

STA 9090

MedGen UID:
435700
Concept ID:
C2607234
Organic Chemical; Pharmacologic Substance
8.

Ubiquitination

The process in which one or more ubiquitin groups are added to a protein. [GOC:ai] [from GO]

MedGen UID:
276919
Concept ID:
C1519751
Molecular Function
9.

Leukemia

Leukemia is cancer of the white blood cells. White blood cells help your body fight infection. Your blood cells form in your bone marrow. In leukemia, the bone marrow produces abnormal white blood cells. These cells crowd out the healthy blood cells, making it hard for blood to do its work. There are different types of leukemia, including. -Acute lymphocytic leukemia. -Acute myeloid leukemia. -Chronic lymphocytic leukemia. -Chronic myeloid leukemia. Leukemia can develop quickly or slowly. Chronic leukemia grows slowly. In acute leukemia, the cells are very abnormal and their number increases rapidly. Adults can get either type; children with leukemia most often have an acute type. Some leukemias can often be cured. Other types are hard to cure, but you can often control them. Treatments may include chemotherapy, radiation and stem cell transplantation. Even if symptoms disappear, you might need therapy to prevent a relapse. NIH: National Cancer Institute.  [from MedlinePlus]

MedGen UID:
9725
Concept ID:
C0023418
Neoplastic Process
10.

Myeloid leukemia

A leukemia that originates from a myeloid cell, that is the blood forming cells of the bone marrow. [from HPO]

MedGen UID:
7320
Concept ID:
C0023470
Neoplastic Process
11.

disease-free survival

MedGen UID:
776920
Concept ID:
CN186048
Finding
12.

Growth control, Y-chromosome influenced

MedGen UID:
358267
Concept ID:
C1868676
Finding
13.

Inhibition

MedGen UID:
5809
Concept ID:
C0021469
Molecular Function
14.

Etomedac

MedGen UID:
906405
Concept ID:
C4082990
Organic Chemical; Pharmacologic Substance
15.

Eto-GRY

MedGen UID:
327829
Concept ID:
C1564686
Organic Chemical; Pharmacologic Substance
16.

Celltop

MedGen UID:
327828
Concept ID:
C1564684
Organic Chemical; Pharmacologic Substance
17.

Eposin

MedGen UID:
297354
Concept ID:
C1564685
Organic Chemical; Pharmacologic Substance
18.

Onkoposid

MedGen UID:
289888
Concept ID:
C1564692
Organic Chemical; Pharmacologic Substance
19.

Riboposid

MedGen UID:
289017
Concept ID:
C1564693
Organic Chemical; Pharmacologic Substance
20.

Exitop

MedGen UID:
289016
Concept ID:
C1564691
Organic Chemical; Pharmacologic Substance
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