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Macule

MedGen UID:
451035
Concept ID:
C0332573
Sign or Symptom
Synonyms: Macula; Maculae; Macular Lesion
SNOMED CT: Macule (112629002); Macula (112629002); Maculae (112629002)
 
HPO: HP:0012733

Definition

A flat lesion, less than 2 cm in diameter, not raised above the surface of the surrounding skin [from SNOMED CT]

Recent clinical studies

Etiology

Pemov A, Sung H, Hyland PL, Sloan JL, Ruppert SL, Baldwin AM, Boland JF, Bass SE, Lee HJ, Jones KM, Zhang X; NISC Comparative Sequencing Program., Mullikin JC, Widemann BC, Wilson AF, Stewart DR
PLoS Genet 2014 Oct 16;10(10):e1004575. doi: 10.1371/journal.pgen.1004575. PMID: 25329635Free PMC Article
Tong HX, Li M, Zhang Y, Zhu J, Lu WQ
Genet Mol Res 2012 Aug 29;11(3):2972-8. doi: 10.4238/2012.July.10.6. PMID: 22869071
Lozano LM, López V, Ríos J, Popescu D, Torner P, Castillo F, Maculé F
ScientificWorldJournal 2012;2012:249391. Epub 2012 Apr 30 doi: 10.1100/2012/249391. PMID: 22623889Free PMC Article
Shen ZY, Liu W, Bao ZX, Zhou ZT, Wang LZ
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011 Jul;112(1):e21-5. doi: 10.1016/j.tripleo.2011.02.040. PMID: 21669356
Nuñez M, Nuñez E, Sastre S, Del-Val JL, Segur JM, Macule F
Orthopedics 2008 Aug;31(8):753. PMID: 19292422

Diagnosis

Ohata C
Cutis 2016 Mar;97(3):169-72. PMID: 27023079
J N J Dent Assoc 2015 Summer;86(3):14, 19. PMID: 26495673
Curto-Barredo L, Vicente A, Rovira C, García-Diez E, Pujol RM, González-Enseñat MA
Pediatr Dermatol 2015 Jul-Aug;32(4):536-8. Epub 2014 Dec 22 doi: 10.1111/pde.12487. PMID: 25529319
Ares O, Lozano LM, Medrano-Nájera C, Popescu D, Martínez-Pastor JC, Segur JM, Maculé F
Arch Orthop Trauma Surg 2014 May;134(5):713-7. Epub 2014 Feb 14 doi: 10.1007/s00402-014-1951-6. PMID: 24525798
Shen ZY, Liu W, Bao ZX, Zhou ZT, Wang LZ
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011 Jul;112(1):e21-5. doi: 10.1016/j.tripleo.2011.02.040. PMID: 21669356

Therapy

Ramalho KM, Rocha RG, Correa-Aranha AC, Cunha SR, Simões A, Campos L, Eduardo Cde P
Photodiagnosis Photodyn Ther 2015 Jun;12(2):321-3. Epub 2015 Mar 10 doi: 10.1016/j.pdpdt.2015.02.005. PMID: 25770054
Ares O, Lozano LM, Medrano-Nájera C, Popescu D, Martínez-Pastor JC, Segur JM, Maculé F
Arch Orthop Trauma Surg 2014 May;134(5):713-7. Epub 2014 Feb 14 doi: 10.1007/s00402-014-1951-6. PMID: 24525798
Lozano LM, López V, Ríos J, Popescu D, Torner P, Castillo F, Maculé F
ScientificWorldJournal 2012;2012:249391. Epub 2012 Apr 30 doi: 10.1100/2012/249391. PMID: 22623889Free PMC Article
Walsh SN, Jorizzo JL, Haverstock C, Sangüeza OP
Am J Dermatopathol 2008 Apr;30(2):194-5. doi: 10.1097/DAD.0b013e318162eaca. PMID: 18360131
Maculé F, Sastre S, Lasurt S, Sala P, Segur JM, Mallofré C
Acta Orthop Belg 2005 Dec;71(6):714-7. PMID: 16459863

Prognosis

Pemov A, Sung H, Hyland PL, Sloan JL, Ruppert SL, Baldwin AM, Boland JF, Bass SE, Lee HJ, Jones KM, Zhang X; NISC Comparative Sequencing Program., Mullikin JC, Widemann BC, Wilson AF, Stewart DR
PLoS Genet 2014 Oct 16;10(10):e1004575. doi: 10.1371/journal.pgen.1004575. PMID: 25329635Free PMC Article
Segur JM, Vilchez-Cavazos F, Martinez-Pastor JC, Macule F, Suso S, Acosta-Olivo C
Arch Orthop Trauma Surg 2014 Sep;134(9):1311-5. Epub 2014 Jul 23 doi: 10.1007/s00402-014-2064-y. PMID: 25052772
Sierra JM, García S, Martínez-Pastor JC, Tomás X, Gallart X, Vila J, Bori G, Maculé F, Mensa J, Riba J, Soriano A
Arch Orthop Trauma Surg 2011 Oct;131(10):1357-61. Epub 2011 May 11 doi: 10.1007/s00402-011-1307-4. PMID: 21559986
Walsh SN, Jorizzo JL, Haverstock C, Sangüeza OP
Am J Dermatopathol 2008 Apr;30(2):194-5. doi: 10.1097/DAD.0b013e318162eaca. PMID: 18360131
Maculé F, Sastre S, Lasurt S, Sala P, Segur JM, Mallofré C
Acta Orthop Belg 2005 Dec;71(6):714-7. PMID: 16459863

Clinical prediction guides

Pemov A, Sung H, Hyland PL, Sloan JL, Ruppert SL, Baldwin AM, Boland JF, Bass SE, Lee HJ, Jones KM, Zhang X; NISC Comparative Sequencing Program., Mullikin JC, Widemann BC, Wilson AF, Stewart DR
PLoS Genet 2014 Oct 16;10(10):e1004575. doi: 10.1371/journal.pgen.1004575. PMID: 25329635Free PMC Article
Ares O, Lozano LM, Medrano-Nájera C, Popescu D, Martínez-Pastor JC, Segur JM, Maculé F
Arch Orthop Trauma Surg 2014 May;134(5):713-7. Epub 2014 Feb 14 doi: 10.1007/s00402-014-1951-6. PMID: 24525798
Lozano LM, López V, Ríos J, Popescu D, Torner P, Castillo F, Maculé F
ScientificWorldJournal 2012;2012:249391. Epub 2012 Apr 30 doi: 10.1100/2012/249391. PMID: 22623889Free PMC Article
Shen ZY, Liu W, Bao ZX, Zhou ZT, Wang LZ
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011 Jul;112(1):e21-5. doi: 10.1016/j.tripleo.2011.02.040. PMID: 21669356
Husain S, Scher RK, Silvers DN, Ackerman AB
J Am Acad Dermatol 2006 Apr;54(4):664-7. doi: 10.1016/j.jaad.2005.11.1098. PMID: 16546590

Recent systematic reviews

Ruiz Ibán MA, Maculé F, Torner P, Gil Garay E, Oteo-Álvaro A, López Millán JM, Díaz Heredia J, Loza E
Rev Esp Cir Ortop Traumatol 2015 May-Jun;59(3):186-99. Epub 2014 Nov 27 doi: 10.1016/j.recot.2014.09.005. PMID: 25435293
Diaz-Ledezma C, Parvizi J, Zhou Y, Antoci V, Ducheyne P, Freiberg A, Rangel GG, Han SB, Hickok N, Higuera C, Ketonis C, Korkusuz F, Kruczynski J, Macule F, Markuszewski J, Marín-Peña O, Nathwani D, Noble P, Ong K, Ono N, Parvizi MS, Post Z, Rivero-Boschert S, Schaer T, Shapiro I
J Orthop Res 2014 Jan;32 Suppl 1:S90-7. doi: 10.1002/jor.22552. PMID: 24464902
Diaz-Ledezma C, Parvizi J, Zhou Y, Antoci V, Ducheyne P, Freiberg A, Garcia Rangel G, Han SB, Hickok N, Higuera C, Ketonis C, Korkusuz F, Kruczynski J, Macule F, Markuszewski J, Marín-Peña O, Nathwani D, Noble P, Ong K, Ono N, Parvizi MS, Post Z, Rivero-Boschert S, Schaer T, Shapiro I
J Arthroplasty 2014 Feb;29(2 Suppl):71-6. Epub 2013 Dec 17 doi: 10.1016/j.arth.2013.09.039. PMID: 24360496
Muñoz-Mahamud E, Popescu D, Nuñez E, Lozano LM, Nuñez M, Sastre S, Torner P, Segur JM, Maculé F
Knee Surg Sports Traumatol Arthrosc 2011 Sep;19(9):1467-72. Epub 2011 Feb 3 doi: 10.1007/s00167-011-1402-7. PMID: 21290107
Taïeb A, Picardo M; VETF Members.
Pigment Cell Res 2007 Feb;20(1):27-35. doi: 10.1111/j.1600-0749.2006.00355.x. PMID: 17250545

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