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Aneurysm

MedGen UID:
8076
Concept ID:
C0002940
Disease or Syndrome
Synonyms: Aneurysmal dilatation; Aneurysmal disease; Aneurysms
SNOMED CT: Aneurysm (85659009); Aneurysmal dilatation (85659009); Aneurysm (432119003)
 
HPO: HP:0002617

Definition

An aneurysm is a bulge or ballooning in the wall of an artery. Arteries are blood vessels that carry oxygen-rich blood from the heart to other parts of the body. If an aneurysm grows large, it can burst and cause dangerous bleeding or even death. . Most aneurysms occur in the aorta, the main artery that runs from the heart through the chest and abdomen. Aneurysms also can happen in arteries in the brain, heart and other parts of the body. If an aneurysm in the brain bursts, it causes a stroke. Aneurysms can develop and become large before causing any symptoms. Often doctors can stop aneurysms from bursting if they find and treat them early. They use imaging tests to find aneurysms. Often aneurysms are found by chance during tests done for other reasons. Medicines and surgery are the two main treatments for aneurysms. . NIH: National Heart, Lung, and Blood Institute.  [from MedlinePlus]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAneurysm

Conditions with this feature

Polyarteritis nodosa
MedGen UID:
14681
Concept ID:
C0031036
Disease or Syndrome
Childhood-onset polyarteritis nodosa is an autosomal recessive systemic vascular inflammatory disorder characterized mainly by involvement of the skin, nervous system, kidney, and gastrointestinal tract. There is considerable variability in the severity and age at onset, although most patients have onset of symptoms in the first decade. Features include recurrent ischemic stroke affecting the small vessels of the brain and resulting in neurologic dysfunction, recurrent fever, elevated acute-phase proteins, myalgias, and livedo racemosa or reticularis with an inflammatory vasculitis on biopsy. Some patients develop hypertension, aneurysms, or ischemic necrosis of the digits (summary by Zhou et al., 2014 and Navon Elkan et al., 2014). Some patients present with clinical immunodeficiency (van Eyck et al., 2014).
Aneurysm of interventricular septum
MedGen UID:
234648
Concept ID:
C1387721
Anatomical Abnormality
Arrhythmogenic right ventricular cardiomyopathy, type 9
MedGen UID:
373205
Concept ID:
C1836906
Disease or Syndrome
Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is characterized by progressive fibrofatty replacement of the myocardium that predisposes to ventricular tachycardia and sudden death in young individuals and athletes. It primarily affects the right ventricle; with time, it may also involve the left ventricle. The presentation of disease is highly variable even within families, and some affected individuals may not meet established clinical criteria. The mean age at diagnosis is 31 years (±13; range: 4-64 years).
Vascular hyalinosis
MedGen UID:
376398
Concept ID:
C1848590
Disease or Syndrome

Recent clinical studies

Etiology

Raychev R, Tateshima S, Vinuela F, Sayre J, Jahan R, Gonzalez N, Szeder V, Duckwiler G
Interv Neuroradiol 2016 Feb;22(1):34-41. Epub 2015 Nov 3 doi: 10.1177/1591019915609125. PMID: 26537850Free PMC Article
Elsharawy MA, Elsaid A, Al-Dhafery B, Alghnimi I, Almabyouq F
Vascular 2016 Oct;24(5):454-60. Epub 2015 Oct 29 doi: 10.1177/1708538115611069. PMID: 26519256
Guang LJ, Wang JF, Wei BJ, Gao K, Huang Q, Zhai RY
Medicine (Baltimore) 2015 Dec;94(52):e2073. doi: 10.1097/MD.0000000000002073. PMID: 26717355Free PMC Article
Balaz P, Björck M
J Vasc Access 2015 Nov-Dec;16(6):446-53. Epub 2015 May 30 doi: 10.5301/jva.5000391. PMID: 26044900
Sharples A, Kay M, Sykes T, Fox A, Houghton A
Vascular 2015 Oct;23(5):494-7. Epub 2014 Oct 20 doi: 10.1177/1708538114557070. PMID: 25331071

Diagnosis

Ventarola DJ, Labropoulos NN, Landau DS, Tassiopoulos AK, Loh SA
Ann Vasc Surg 2016 Aug;35:207.e11-6. Epub 2016 May 27 doi: 10.1016/j.avsg.2016.01.049. PMID: 27238986
Elsharawy MA, Elsaid A, Al-Dhafery B, Alghnimi I, Almabyouq F
Vascular 2016 Oct;24(5):454-60. Epub 2015 Oct 29 doi: 10.1177/1708538115611069. PMID: 26519256
Yasuda S, Imoto K, Uchida K, Uranaka Y, Kurosawa K, Masuda M
Asian Cardiovasc Thorac Ann 2016 Feb;24(2):187-9. Epub 2014 Oct 6 doi: 10.1177/0218492314553993. PMID: 25293415
Laurenzi A, Ettorre GM, Lionetti R, Meniconi RL, Colasanti M, Vennarecci G
Dig Liver Dis 2015 Nov;47(11):918-23. Epub 2015 Jun 19 doi: 10.1016/j.dld.2015.06.003. PMID: 26188840
Sharples A, Kay M, Sykes T, Fox A, Houghton A
Vascular 2015 Oct;23(5):494-7. Epub 2014 Oct 20 doi: 10.1177/1708538114557070. PMID: 25331071

Therapy

Ben Abdallah I, El Batti S, Julia P, Alsac JM
Ann Thorac Surg 2017 Jan;103(1):e61-e63. doi: 10.1016/j.athoracsur.2016.07.005. PMID: 28007277
Kodama A, Kurita T, Kato O, Suzuki T
Heart Vessels 2016 Nov;31(11):1882-1885. Epub 2016 Jan 27 doi: 10.1007/s00380-016-0799-9. PMID: 26815559
Kim BM, Kim DJ, Kim DI
Korean J Radiol 2016 Jan-Feb;17(1):151-8. Epub 2016 Jan 6 doi: 10.3348/kjr.2016.17.1.151. PMID: 26798228Free PMC Article
Elsharawy MA, Elsaid A, Al-Dhafery B, Alghnimi I, Almabyouq F
Vascular 2016 Oct;24(5):454-60. Epub 2015 Oct 29 doi: 10.1177/1708538115611069. PMID: 26519256
Sharples A, Kay M, Sykes T, Fox A, Houghton A
Vascular 2015 Oct;23(5):494-7. Epub 2014 Oct 20 doi: 10.1177/1708538114557070. PMID: 25331071

Prognosis

Xiao Y, Wang LP, Yang YK, Tian T, Yang KQ, Sun X, Jiang Y, Liu YX, Zhou XL, Li JJ
Am J Med Sci 2016 Jan;351(1):101-10. doi: 10.1016/j.amjms.2015.10.006. PMID: 26802765
Raychev R, Tateshima S, Vinuela F, Sayre J, Jahan R, Gonzalez N, Szeder V, Duckwiler G
Interv Neuroradiol 2016 Feb;22(1):34-41. Epub 2015 Nov 3 doi: 10.1177/1591019915609125. PMID: 26537850Free PMC Article
Yamamoto T, Miyazaki T, Kurashima Y, Ohata K, Okawa M, Tanaka S, Uenishi T
Osaka City Med J 2015 Dec;61(2):113-23. PMID: 26995855
Balaz P, Björck M
J Vasc Access 2015 Nov-Dec;16(6):446-53. Epub 2015 May 30 doi: 10.5301/jva.5000391. PMID: 26044900
Matsumoto T, Ishizuka M, Iso Y, Kita J, Kubota K
Int Surg 2015 Apr;100(4):765-9. doi: 10.9738/INTSURG-D-14-00127.1. PMID: 25875563Free PMC Article

Clinical prediction guides

Lococo F, Tusini N, Brandi L, Leuzzi G, Galeone C, Paci M, Rapicetta C
Vasc Endovascular Surg 2016 Aug;50(6):458-9. Epub 2016 Jun 22 doi: 10.1177/1538574416655891. PMID: 27334477
Raychev R, Tateshima S, Vinuela F, Sayre J, Jahan R, Gonzalez N, Szeder V, Duckwiler G
Interv Neuroradiol 2016 Feb;22(1):34-41. Epub 2015 Nov 3 doi: 10.1177/1591019915609125. PMID: 26537850Free PMC Article
Balaz P, Björck M
J Vasc Access 2015 Nov-Dec;16(6):446-53. Epub 2015 May 30 doi: 10.5301/jva.5000391. PMID: 26044900
Qureshi AI, Qureshi MH, Mohindroo T, Khan AA, Dingmann K, Sherr GT, Suri MF
J Endovasc Ther 2014 Dec;21(6):861-6. doi: 10.1583/14-4789R.1. PMID: 25453892
Nakagawa I, Park HS, Hironaka Y, Wada T, Kichikawa K, Nakase H
J Stroke Cerebrovasc Dis 2014 Nov-Dec;23(10):e461-5. Epub 2014 Oct 3 doi: 10.1016/j.jstrokecerebrovasdis.2014.07.012. PMID: 25284720

Recent systematic reviews

Fendri J, Palcau L, Cameliere L, Coffin O, Felisaz A, Gouicem D, Dufranc J, Laneelle D, Berger L
Ann Vasc Surg 2017 Feb;39:228-235. Epub 2016 Aug 12 doi: 10.1016/j.avsg.2016.05.115. PMID: 27531094
Laurenzi A, Ettorre GM, Lionetti R, Meniconi RL, Colasanti M, Vennarecci G
Dig Liver Dis 2015 Nov;47(11):918-23. Epub 2015 Jun 19 doi: 10.1016/j.dld.2015.06.003. PMID: 26188840
von Stumm M, Teufelsbauer H, Reichenspurner H, Debus ES
Eur J Vasc Endovasc Surg 2015 Sep;50(3):351-9. Epub 2015 Jun 29 doi: 10.1016/j.ejvs.2015.04.036. PMID: 26138062
Balaz P, Björck M
J Vasc Access 2015 Nov-Dec;16(6):446-53. Epub 2015 May 30 doi: 10.5301/jva.5000391. PMID: 26044900
Kordzadeh A, D'Espiney Barbara RM, Ahmad AS, Hanif MA, Panayiotopoulos YP
J Vasc Access 2015 Jan-Feb;16(1):5-12. Epub 2014 Sep 2 doi: 10.5301/jva.5000297. PMID: 25198824

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