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Items: 1 to 20 of 21

1.

Infection

Invasion of the host organism by microorganisms that can cause pathological conditions or diseases. [from MeSH]

MedGen UID:
811352
Concept ID:
C3714514
Pathologic Function
2.

Fever

A fever is a body temperature that is higher than normal. It is not an illness. It is part of your body's defense against infection. Most bacteria and viruses that cause infections do well at the body's normal temperature (98.6 F). A slight fever can make it harder for them to survive. Fever also activates your body's immune system. Infections cause most fevers. There can be many other causes, including. - Medicines. - Heat exhaustion. - Cancers. - Autoimmune diseases. Treatment depends on the cause of your fever. Your health care provider may recommend using over-the-counter medicines such as acetaminophen or ibuprofen to lower a very high fever. Adults can also take aspirin, but children with fevers should not take aspirin. It is also important to drink enough liquids to prevent dehydration.  [from MedlinePlus]

MedGen UID:
5169
Concept ID:
C0015967
Sign or Symptom
3.

Infections

MedGen UID:
678472
Concept ID:
C0851162
Disease or Syndrome
4.

Spelters fever

MedGen UID:
538578
Concept ID:
C0264454
Disease or Syndrome
5.

PROGRESSIVE ENCEPHALOMYELITIS WITH RIGIDITY

MedGen UID:
349287
Concept ID:
C1861457
Disease or Syndrome
6.

Frequent

Coming at short intervals or in great quantities. [from NCI]

MedGen UID:
87144
Concept ID:
C0332183
Temporal Concept
7.

Viral disease

Viruses are capsules with genetic material inside. They are very tiny, much smaller than bacteria. Viruses cause familiar infectious diseases such as the common cold, flu and warts. They also cause severe illnesses such as HIV/AIDS, smallpox and hemorrhagic fevers. . Viruses are like hijackers. They invade living, normal cells and use those cells to multiply and produce other viruses like themselves. This eventually kills the cells, which can make you sick. Viral infections are hard to treat because viruses live inside your body's cells. They are protected from medicines, which usually move through your bloodstream. Antibiotics do not work for viral infections. There are a few antiviral medicines available. Vaccines can help prevent you from getting many viral diseases. NIH: National Institute of Allergy and Infectious Diseases.  [from MedlinePlus]

MedGen UID:
53027
Concept ID:
C0042769
Disease or Syndrome
8.

Ebola virus disease

Ebola hemorrhagic fever is caused by a virus. It is a severe and often fatal disease. It can affect humans and other primates. Researchers believe that the virus first spreads from an infected animal to a human. It can then spread from human to human through direct contact with a patient's blood or secretions. Symptoms of Ebola may appear anywhere from 2 to 21 days after exposure to the virus. Symptoms usually include. -Fever. -Headache. -Joint and muscle aches. -Weakness. -Diarrhea. -Vomiting. -Stomach pain. -Lack of appetite. Other symptoms including rash, red eyes, and internal and external bleeding, may also occur. The early symptoms of Ebola are similar to other, more common, diseases. This makes it difficult to diagnose Ebola in someone who has been infected for only a few days. However, if a person has the early symptoms of Ebola and there is reason to suspect Ebola, the patient should be isolated. It is also important to notify public health professionals. Lab tests can confirm whether the patient has Ebola. There is no cure for Ebola. Treatment involves supportive care such as fluids, oxygen, and treatment of complications. Some people who get Ebola are able to recover, but many do not. Centers for Disease Control and Prevention.  [from MedlinePlus]

MedGen UID:
129219
Concept ID:
C0282687
Disease or Syndrome
9.

Sepsis

Sepsis is a serious illness. It happens when your body has an overwhelming immune response to a bacterial infection. The chemicals released into the blood to fight the infection trigger widespread inflammation. This leads to blood clots and leaky blood vessels. They cause poor blood flow, which deprives your body's organs of nutrients and oxygen. In severe cases, one or more organs fail. In the worst cases, blood pressure drops and the heart weakens, leading to septic shock. Anyone can get sepsis, but the risk is higher in. -People with weakened immune systems. -Infants and children. -The elderly. -People with chronic illnesses, such as diabetes, AIDS, cancer, and kidney or liver disease. -People suffering from a severe burn or physical trauma. Common symptoms of sepsis are fever, chills, rapid breathing and heart rate, rash, confusion, and disorientation. Doctors diagnose sepsis using a blood test to see if the number of white blood cells is abnormal. They also do lab tests that check for signs of infection. People with sepsis are usually treated in hospital intensive care units. Doctors try to treat the infection, sustain the vital organs, and prevent a drop in blood pressure. Many patients receive oxygen and intravenous (IV) fluids. Other types of treatment, such as respirators or kidney dialysis, may be necessary. Sometimes, surgery is needed to clear up an infection. NIH: National Institute of General Medical Sciences.  [from MedlinePlus]

MedGen UID:
69314
Concept ID:
C0243026
Disease or Syndrome
10.

Systemic Inflammatory Response Syndrome

A serious condition in which there is inflammation throughout the whole body. It may be caused by a severe bacterial infection (sepsis), trauma, or pancreatitis. It is marked by fast heart rate, low blood pressure, low or high body temperature, and low or high white blood cell count. The condition may lead to multiple organ failure and shock. [from NCI_NCI-GLOSS]

MedGen UID:
69303
Concept ID:
C0242966
Disease or Syndrome
11.

Disease due to Filoviridae

Infections with viruses of the family FILOVIRIDAE. The infections in humans consist of a variety of clinically similar viral hemorrhagic fevers but the natural reservoir host is unknown. [from MeSH]

MedGen UID:
67006
Concept ID:
C0242917
Disease or Syndrome
12.

Mononegavirales Infections

Infections with viruses of the order MONONEGAVIRALES. The concept includes FILOVIRIDAE INFECTIONS; PARAMYXOVIRIDAE INFECTIONS; and RHABDOVIRIDAE INFECTIONS. [from MeSH]

MedGen UID:
67005
Concept ID:
C0242916
Disease or Syndrome
13.

Sepsis

Systemic inflammatory response to infection. [from HPO]

MedGen UID:
48626
Concept ID:
C0036690
Disease or Syndrome
14.

Pyemia

Septicemia caused by pyogenic microorganisms (e.g., STAPHYLOCOCCUS; BACILLUS), resulting in the formation of secondary foci of SUPPURATION and multiple ABSCESSES. [from MeSH]

MedGen UID:
18779
Concept ID:
C0034189
Pathologic Function
15.

Viremia

The presence of viruses in the blood. [from MeSH]

MedGen UID:
12097
Concept ID:
C0042749
Disease or Syndrome
16.

RNA Virus Infections

Diseases caused by RNA VIRUSES. [from MeSH]

MedGen UID:
11250
Concept ID:
C0035690
Disease or Syndrome
17.

Interferon Type I

Interferon secreted by leukocytes, fibroblasts, or lymphoblasts in response to viruses or interferon inducers other than mitogens, antigens, or allo-antigens. They include alpha- and beta-interferons (INTERFERON-ALPHA and INTERFERON-BETA). [from MeSH]

MedGen UID:
9509
Concept ID:
C0021743
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
18.

Viral hemorrhagic fever

Viral hemorrhagic fevers (VHFs) are a group of illnesses caused by four families of viruses. These include the Ebola and Marburg, Lassa fever, and yellow fever viruses. VHFs have common features: they affect many organs, they damage the blood vessels, and they affect the body's ability to regulate itself. Some VHFs cause mild disease, but some, like Ebola or Marburg, cause severe disease and death. VHFs are found around the world. Specific diseases are usually limited to areas where the animals that carry them live. For example, Lassa fever is limited to rural areas of West Africa where rats and mice carry the virus. The risk for travelers is low, but you should avoid visiting areas where there are disease outbreaks. Because there are no effective treatments for some of these viral infections, there is concern about their use in bioterrorism. Centers for Disease Control and Prevention.  [from MedlinePlus]

MedGen UID:
9213
Concept ID:
C0019104
Disease or Syndrome
19.

Interferon-alpha

a protein produced by the body in response to an infection [from CHV]

MedGen UID:
7985
Concept ID:
C0002199
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
20.

Inflammation

A localized protective response resulting from injury or destruction of tissues. Inflammation serves to destroy, dilute, or wall off both the injurious agent and the injured tissue. In the acute phase, inflammation is characterized by the signs of pain, heat, redness, swelling, and loss of function. Histologically, inflammation involves a complex series of events, including dilatation of arterioles, capillaries, and venules, with increased permeability and blood flow; exudation of fluids, including plasma proteins; and leukocyte migration into the site of inflammation. [from NCI]

MedGen UID:
7072
Concept ID:
C0021368
Pathologic Function
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