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Items: 7

1.

Darunavir

An HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alone, it is administered in combination with other ANTI-HIV AGENTS. [from MeSH]

MedGen UID:
252001
Concept ID:
C1435444
Organic Chemical; Pharmacologic Substance
2.

Lopinavir

A peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation. Lopinavir is less affected by binding to serum proteins than the structurally-related drug ritonavir. [from NCI]

MedGen UID:
145897
Concept ID:
C0674432
Organic Chemical; Pharmacologic Substance
3.

Ritonavir

A peptidomimetic agent that inhibits both HIV-1 and HIV-2 proteases. Ritonavir is highly inhibited by serum proteins but boosts the effect of other HIV proteases by blocking their degradation by cytochrome P450. [from NCI]

MedGen UID:
132886
Concept ID:
C0292818
Organic Chemical; Pharmacologic Substance
4.

Lopinavir+ritonavir

A fixed combination of two protease inhibitors, lopinavir and ritonavir, used to treat human immunodeficiency virus (HIV) infection. The ritonavir in the combination drug increases the concentration and biological half-life of lopinavir but is not present in sufficient concentration to act as a protease inhibitor. [from NCI]

MedGen UID:
215250
Concept ID:
C0939237
Pharmacologic Substance
5.

Hiv

An infection caused by the human immunodeficiency virus. [from NCI]

MedGen UID:
5583
Concept ID:
C0019693
Disease or Syndrome
6.

UIC-94017

MedGen UID:
314188
Concept ID:
C1721346
Organic Chemical; Pharmacologic Substance
7.

Prezista

MedGen UID:
314187
Concept ID:
C1721345
Organic Chemical; Pharmacologic Substance
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